Search clinical trials for: QTc prolongation effect

Total 148224 results

Richmond Research Institute
Richmond Pharmacology Limited

Completed

Effect of Glucose on QTc Interval in Type 1 Diabetes

Diabetes

United Kingdom
Beni-Suef University

Completed

Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia

QTc Prolongation, Hyperglycemia, Hypoglycemia

Egypt
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of GMI-1070 on Qtc Intervals in Healthy African-American Adult Subjects

Healthy

United States
Nobelpharma

Completed

Investigation of Arrhythmogenic Effect of NPC-15 (NPC-15-7)

Qt Interval, Variation in

Japan
Konkuk University Medical Center

Completed

Ramosetron Pre-treatment for PONV and QT Prolongation

PONV | Prolonged QTc Interval

Korea, Republic of
Yonsei University

Completed

Effect of Dexmedetomidine on Heart-rate Corrected QT(QTc) Interval Prolongation During Robotic-assisted Laparoscopic Radical Prostatectomy -Randomized Blind Clinical Trial-

Prostate Cancer | Robotic Surgery

Korea, Republic of
Heron Therapeutics

Completed

A Phase I Study of the Effects of APF530 Exposure, Granisetron and Moxifloxacin

Healthy

United States
Severance Hospital

Completed

The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation in Normotensive and Hypertensive Patients

Intubation, Intratracheal

Korea, Republic of
Mahidol University

Completed

Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management

Pain, Chronic

Thailand
C.R.Darnall Army Medical Center
Madigan Army Medical Center

Completed

Ondansetron and the QT Interval In Adult Emergency Department Patients

Ondansetron

United States
Severance Hospital

Completed

The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation Under Propofol-remifentanil Anesthesia in Elderly Patients

General Surgery With Endotracheal Intubation

Korea, Republic of
Pfizer

Terminated

A Pharmacokinetic And QT Study Of CP-751,871 In Healthy Subjects

Healthy Volunteers

United States
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study

Healthy

United States
J. Uriach and Company

Completed

Evaluation of Possible Effects on the QT/ QTc Interval of Rupatadine in Healthy Volunteers

Human Experimentation (Human Volunteers)

Spain
Amgen

Not yet recruiting

A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants

Basic Science
University of Copenhagen
University of Southern Denmark; Danish Research Centre for Magnetic Resonance; Faculty of Health, Medicine and Life Sciences, Maastricht University and other collaborators

Recruiting

Effect of Sleep Extension on Overweight and Learning in Children (More2Sleep)

Child Behavior | Child Development | Child Obesity | Sleep Duration

Denmark
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Study to Evaluate the Effect of Jaktinib on QT/QTc Interval in Healthy Participants

Healthy Participants

China
University of Utah

Recruiting

Effect of Sleep Extension on Ceramides in People With Overweight and Obesity

Sleep | Type 2 Diabetes | Sleep Deprivation | Overweight and Obesity | Insulin Sensitivity | Sleep Hygiene | Eating Habit | Lifestyle Factors | Insufficient Sleep Syndrome

United States
University of Mostar

Not yet recruiting

The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth

Preterm Birth
Lina Bergman
The Swedish Research Council

Recruiting

PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia (PI4)

Preeclampsia

Sweden
Ataturk University

Recruiting

The Effect of Combined Spinal Epidural Anaesthesia on QTc Interval Undergoing Cesarean Section

Analgesia

Turkey
Novartis Pharmaceuticals

Recruiting

Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Spain, France
Universitaire Ziekenhuizen KU Leuven
Fonds voor Wetenschappelijk Reumaonderzoek (FWRO)

Not yet recruiting

Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-guided Dose Reduction in Patients With Rheumatoid Arthritis (RITUXERA)

Rheumatoid Arthritis

Belgium
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
Thryv Therapeutics, Inc.

Recruiting

Study of LQT-1213 on QTc-induced Prolongation in Healthy Adult Subjects (Part1) and on Congenital Long QT in Patients Diagnosed With Type 2 or 3 Long QT Syndrome (Part 2).

Long QT Syndrome

United States
Murdoch Childrens Research Institute

Recruiting

Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG

Neoplasms | Cardiac Arrhythmia

Australia
Auburn University

Not yet recruiting

Effects of Vitamin D on Skeletal Muscle Strength in Resistance Trained Adult Females

Nutrition Status | Sports Nutritional Sciences | Nutritional Requirements
Angion Biomedica Corp
Quotient Sciences

Not yet recruiting

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Healthy Volunteer

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Ventricular Repolarization in Patients With Premature Ovarian Insufficiency (QT-IOP) (QT-IOP)

Premature Ovarian Insufficiency

France
Washington University School of Medicine

Recruiting

Metabolic Effects of Sleep Extension in People With Obesity

Obesity | Insulin Resistance

United States
Burzynski Research Institute

Not yet recruiting

Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma (DBSG)

Brain Stem Glioma
Massachusetts General Hospital
University of Colorado, Denver; Mayo Clinic; National Heart, Lung, and Blood... and other collaborators

Recruiting

Genetics of QT Prolongation With Antiarrhythmics (DOFEGEN)

Long QT Syndrome | Drug Toxicity

United States
Novartis Pharmaceuticals

Recruiting

Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

Multiple Sclerosis

Italy, Spain, United States, Germany, France, Serbia, Austria, Brazil, Bulgaria, Canada, Croatia, Estonia, Latvia, Mexico, Poland, Puerto Rico, Russian Federation, Sweden, Turkey, Ukraine, United Kingdom, Lithuania, Netherlands, Slovakia and more
AstraZeneca

Completed

A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy Participants

Healthy Participants

Germany
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Rhythm Pharmaceuticals, Inc.

Completed

Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

Healthy

United States
Sanofi

Terminated

Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors (TusaRav-QT)

Neoplasm

France, United States, Belgium, Spain, Turkey
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants

Pain

United States
GlaxoSmithKline

Completed

Concentration-QT Study of Paroxetine in Healthy Adults

Anxiety Disorders

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019) (TQT)

Schizophrenia

United States
Constellation Pharmaceuticals

Completed

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies

Solid Tumor | Advanced Malignancies | Hematological Malignancy

Spain, United States, Georgia
Pfizer

Completed

A Study to Investigate the Effects of Sisunatovir on QTc Interval in Healthy Adult Participants.

Healthy

United States
Tianjin Medical University

Completed

Effect of Virtual Reality on Patients With Acute Pain After Thoracoscopic Surgery

Acute Postoperative Pain | Virtual Reality | Thoracic Surgery, Video-Assisted

China
Reata, a wholly owned subsidiary of Biogen

Completed

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

Healthy Volunteers

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants

Healthy

United States
Italfarmaco

Completed

Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval

Duchenne and Becker Muscular Dystrophy | Polycytemia Vera

Canada
AN2 Therapeutics, Inc

Completed

A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects

Healthy Volunteers

United States
Cytokinetics

Completed

Study to Evaluate the Effect of Aficamten Administration on QT/QTc Interval

Healthy Participants

United States
Oswaldo Cruz Foundation
University of Sao Paulo; Federal University of Juiz de Fora

Active, not recruiting

The Role of BCG Vaccine in the Clinical Evolution of COVID-19 and in the Efficacy of Anti-SARS-CoV-2 Vaccines (SARS-CoV-2)

COVID-19

Brazil

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