Search clinical trials for: Rare Diseases

Total 372700 results

University of Calgary

Not yet recruiting

Head COOLing in iscHemic Stroke Patients Undergoing EndovAscular Thrombectomy: a Feasibility and Safety stuDy (COOLHEAD-2-CAN)

Stroke, Acute
Taumedika s.r.l.
Nextrasearch S.r.l.s.

Not yet recruiting

Pre-marketing Clinical Trial to Evaluate the Safety and Efficacy of the Filler of Hyaluronic Acid Recombinant Collagen

Scar | Laxity; Skin | Wrinkle
European Institute of Oncology

Recruiting

Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology

Lymphoma | Leukemia | Aplastic Anemia | Leukemia, Acute | Leukemia, Chronic

Italy
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections (LUCY-1)

Cytomegalovirus Infection

France
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
UNICANCER
GlaxoSmithKline; National Cancer Institute, France

Not yet recruiting

Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI (Pan-MSI-ACSE)

Soft Tissue Sarcoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Neuroendocrine Carcinoma | Adrenocortical Carcinoma | Small Bowel Adenocarcinoma | Ampulla of Vater Carcinoma | Duodenum Adenocarcinoma

France
Baohui Han

Not yet recruiting

Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy

Extensive-stage Small-cell Lung Cancer

China
Peking Union Medical College Hospital
Obstetrics & Gynecology Hospital of Fudan University

Not yet recruiting

Laser Ablation in the Treatment of High-grade Cervical Lesions

High-Grade Squamous Intraepithelial Lesions
LG Chem

Not yet recruiting

Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors (LB-LR1109)

Urothelial Carcinoma | Malignant Melanoma | Non-small Cell Lung Cancer(NSCLC) | Head and Neck Squamous Cell Carcinoma(HNSCC) | Renal Cell Carcinoma(RCC)
University of Aarhus

Not yet recruiting

Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic Sclerosis (FaeMiCue)

Diarrhea | Systemic Sclerosis

Denmark
Sofwave Medical LTD

Recruiting

Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators

Lax Skin

United States
Gustave Roussy, Cancer Campus, Grand Paris
BeiGene; C2i Genomics

Not yet recruiting

tislelizUMaB in canceR Patients With molEcuLar residuaL Disease (UMBRELLA)

Soft Tissue Sarcoma | Cancer | Lung Cancer | Pancreas Cancer | Colo-rectal Cancer

France
Pensionsversicherungsanstalt

Not yet recruiting

Effectiveness of a Resilience-Based Rehabilitation Program for Patients With Coronary Heart Disease

Acute Coronary Syndrome | Takotsubo Cardiomyopathy | Psychological Resilience
Roswell Park Cancer Institute
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Cannabis Dependence

United States
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
CARsgen Therapeutics Co., Ltd.

Not yet recruiting

Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL

Multiple Myeloma | Primary Plasma Cell Leukemia
National Institute of Allergy and Infectious Diseases...

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

HIV

United States
Mayo Clinic

Recruiting

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia

United States
Leiden University Medical Center
Medical Center Haaglanden; Groene Hart Ziekenhuis; Reinier de Graaf Groep; Alrijne... and other collaborators

Recruiting

Stroke Triage Optimization by Ambulance Paramedics in the Pre-hospital Setting (STROKE-APP)

Stroke, Acute | Pre-hospital Triage | Stroke Treatment | Stroke Code

Netherlands
IRCCS Ospedale San Raffaele

Not yet recruiting

Acanthamoeba and Artificial Intelligence

Artificial Intelligence | Acanthamoeba Keratitis
Riphah International University

Recruiting

Combined Effects of Ba-Duan-Jin Based Deep Breathing Exercises and Forced Expiratory Technique

Chronic Obstructive Pulmonary Disease

Pakistan
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
Duke University
Misophonia Research Fund

Not yet recruiting

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study (MISO-STIM)

Sensory Processing Disorder | Anxiety Disorder | Misophonia | Emotion Dysregulation | Auditory Over Responsivity | Sound Sensitivity

United States
Canwell Biotech Limited

Not yet recruiting

Intratumoral CAN2109 in Subjects With Solid Tumors or Lymphomas

Lymphoma | Solid Tumor

China
University Hospital Plymouth NHS Trust

Not yet recruiting

Splenic Embolisation Decisions (SPEED)

Trauma | Spleen Injury
Meyer Children's Hospital IRCCS

Recruiting

Immunodeficiency and Cancer: Identification of Congenital Immune System Defects Underlying Paediatric Lymphomas

Immune Deficiency

Italy
Defence Medical Rehabilitation Centre, UK
University of Bath

Recruiting

Acute Physiological Responses to Twice Daily Blood Flow Restriction Training

Muscle Weakness | Muscle Damage

United Kingdom
Medical University of Warsaw

Not yet recruiting

Fecal Microbiota Transplantation (FMT) as a Prophylaxis of Necrotizing Enterocolitis (NEC) - Clinical Study

Necrotizing Enterocolitis

Poland
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Target of Suv420h1/2 in Hepatocytes

NAFLD

Italy
NGGT (Suzhou) Biotechnology Co., Ltd.

Not yet recruiting

AAV Gene Therapy Clinical Study in Adult Classic PKU

Phenylketonurias
Rede Optimus Hospitalar SA
Shockwave Medical, Inc.

Not yet recruiting

Shockwave™Peripheral Intravascular Lithotripsy Balloon for Advanced Endovascular Aortic Repair (TEVAR)

Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture | Abdominal Aortic Aneurysm Without Rupture | Thoracic Aortic Aneurysm Without Rupture
Asbjørn Mohr Drewes

Recruiting

The Effect of Naldemedine on Opioid-induced Bowel Dysfunction

Constipation | Opioid-Induced Bowel Dysfunction

Denmark
Inhye Ahn
Loxo Oncology, Inc.

Recruiting

Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Linkoeping University

Not yet recruiting

Evaluation of an Internet Based Education and Support Program for Patients Awaiting Kidney Transplantation (INSERT)

Chronic Kidney Diseases
Mahmoud Reda Elsharkawy

Recruiting

Universal Exercise Unit Versus Functional Electrical Stimulation On Genu Recurvatum In Diplegic Cerebral Palsy

Cerebral Palsy

Egypt
Chang Gung Memorial Hospital
DOTSPACE

Recruiting

First-In-Human Study of PDT to Detect IAH

Intra-Abdominal Hypertension

Taiwan
Kaohsiung Medical University Chung-Ho Memorial...

Recruiting

Efficacy and Safety of Silodosin in the Treatment of Lower Urinary Tract Symptoms in Taiwanese Population.

Human Trichinellosis

Taiwan
Lundquist Institute for Biomedical Innovation at...

Not yet recruiting

Study of Cannabidiol in Sanfilippo Syndrome

Mucopolysaccharidosis III | Sanfilippo Syndrome

United States
Pulmonx Corporation

Recruiting

Zephyr Valve Japan Post-Marketing Surveillance

Emphysema | COPD | Severe Emphysema

Japan
Biocad

Recruiting

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)

Axial Spondyloarthritis

Russian Federation, Belarus
Prof. Dr. Folkert W. Asselbergs
Radboud University Medical Center; University Medical Center Groningen; UMC Utrecht and other collaborators

Not yet recruiting

Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Atrial Fibrillation
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM)

Not yet recruiting

Open Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer Survivors

Colorectal Cancer | Sexual Dysfunction | Anal Cancer
University of Leicester

Recruiting

Developing Personalised Relative Physical Activity Thresholds in COPD. (IMPACT)

Chronic Obstructive Pulmonary Disease

United Kingdom
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
Liaoning Chengda Biotechnology CO., LTD

Recruiting

Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR)

Japanese Encephalitis | Measles | Rubella | Mumps

China
University of Pisa
Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy

Recruiting

Fetal Autonomic Nervous sysTem Evaluation (FANTE)

Pregnancy Complications | Pregnancy Related | Pre-Eclampsia | Fetal Growth Retardation | Fetal Complications | Gestational Diabetes | Pregnancy Disease | ECG Electrode Site Reaction

Italy
Attikon Hospital

Recruiting

Prospective Evaluation of Ultrasound-guided Percutaneous Cholecystostomy With the Trocar Technique

Cholecystitis, Acute | Cholecystitis

Greece
The Third Affiliated hospital of Zhejiang Chinese...
Zhejiang University

Recruiting

Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma

Glioma

China
NaviFUS Corporation
NaviFUS US LLC

Not yet recruiting

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Neoplasms | Glioblastoma | Neoplasms, Nerve Tissue | Brain Tumor | Glioblastoma Multiforme

United States
The University of Texas at Arlington

Recruiting

The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism

Cardiovascular Diseases | Hypertension | Diet

United States

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