Search clinical trials for: Rare Diseases

Total 374787 results

Cagent Vascular LLC

Not yet recruiting

Serrantor OCT Study

Critical Limb Ischemia
University Hospital, Gentofte, Copenhagen
Rigshospitalet, Denmark; The Novo Nordic Foundation; Region Capital Denmark; VIVE... and other collaborators

Not yet recruiting

Cross-sectorial Use of Patient-Reported Outcomes in Chronic Degenerative Shoulder Conditions (C-PRO)

Shoulder Impingement Syndrome | Shoulder Osteoarthritis | Shoulder Capsulitis | Shoulder Impingement | Shoulder Bursitis | Shoulder Disease | Rotator Cuff Syndrome | Rotator Cuff Syndrome of Shoulder and Allied Disorders | Shoulder Frozen

Denmark
TCROSS Co., Ltd.
Kaneka Corporation

Recruiting

Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry)

Stable Angina | Unstable Angina | Non-ST-elevation Acute Coronary Syndrome

Japan
Hebei Medical University Fourth Hospital

Not yet recruiting

To Explore the Efficacy of Hypofractionated Radiotherapy Followed by AG Regimen Chemotherapy Plus Camrelizumab Immunotherapy as Neoadjuvant Therapy for Locally Advanced Pancreatic Cancer

Pancreatic Cancer

China
Peking University Cancer Hospital & Institute

Not yet recruiting

Molecular Imaging of Gastric Cancer Metastatic Lymph Nodes with 99mTc-3PRGD2 Probe.

Stomach Neoplasm | Lymph Node Metastasis | RADIONUCLIDE IMAGING
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive

Asthma | Mild Asthma
ID3 Medical
Abbott; Vascular Science LP GmbH

Not yet recruiting

Investigating Efficacy and Safety of JETi® in Arterial Occlusions in FEM-POP and Prox BTK-Lesions (JETART) (JETART)

Peripheral Arterial Disease
First Affiliated Hospital of Zhejiang University
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML

Myeloid Malignancy | Relapsed/Refractory Acute Myeloid Leukaemia

China
Opna Bio LLC

Not yet recruiting

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
The Christie NHS Foundation Trust
University College London Hospitals; University College, London; Royal Free Hospital...

Not yet recruiting

Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar Cholangiocarcinoma (EMPHATIC)

Cholangiocarcinoma
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
Splice Bio

Recruiting

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene (POLARIS)

Stargardt Disease | Stargardt's Disease | STGD1 | Stargardt
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

A Point-of-care Electrochemical-based Device for Rapid Detection of Fibrinogen on Type A Aortic Dissection Surgery

Hypofibrinogenemia

China
Kafrelsheikh University

Not yet recruiting

Effect of Pully System on Hemiplegic Children

Cerebral Palsy, Spastic

Egypt
Abbott Medical Devices

Recruiting

Acute Response to Left Bundle Branch Area Pacing With SyncAV

Heart Failure

Italy
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

Systemic Sclerosis | Autoimmune Disorders

United States
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.

Platinum-resistant Recurrent Ovarian Cancer

China
UCB Biopharma SRL

Not yet recruiting

An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis (ziMyG+)

Generalized Myasthenia Gravis
Hanlim Pharm. Co., Ltd.

Recruiting

Study to Evaluate Efficacy and Safety of Bronpass Tab. in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Papworth Hospital NHS Foundation Trust

Not yet recruiting

Radial Artery Assessment in Surgical Coronary Revascularisation

Coronary Artery Disease | Coronary Artery Bypass Grafting

United Kingdom
Inova Fairfax Hospital

Not yet recruiting

Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator

Cesarean Section | Opioid Use Disorder | Post-operative Pain, Acute | Opioids; Harmful Use

United States
The Second Hospital of Nanjing Medical University

Recruiting

Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD

Type A Aortic Dissection

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma

T-lymphoblastic Lymphoma | T-lymphoblastic Leukemia

China
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis (coldAPC)

Familial Adenomatous Polyposis | Adenomatous Polyposis Coli | Duodenal Adenoma

Germany
Baylor College of Medicine
M.D. Anderson Cancer Center; William Marsh Rice University; Instituto do Cancer... and other collaborators

Not yet recruiting

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

Suspected or Known Squamous Cell Neoplasia | Prior History of Squamous Cell Dysplasia and /or Neoplasia

Brazil, United States
Boston Children's Hospital

Not yet recruiting

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis (EVmiRNA)

Thrombosis | Congenital Heart Disease | Single-ventricle

United States
King's College Hospital NHS Trust

Recruiting

Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study (ACNH)

Cardiovascular Diseases | Obesity | Cognitive Impairment | Metabolic Disease | Hepatic Steato-Fibrosis

United Kingdom
University of Aarhus
Aarhus University Hospital; Aalborg University Hospital; Gødstrup Hospital; Regional...

Not yet recruiting

Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture (BEAN)

Achilles Tendon Rupture
Hospices Civils de Lyon

Not yet recruiting

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases (GENIALII)

Autoimmune Diseases | Genetic Disease | Autoinflammatory Disease | Systemic Lupus

France
Priovant Therapeutics, Inc.

Not yet recruiting

A 12-Week Open-Label Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Skin-Predominant Dermatomyositis

Dermatomyositis | Dermatomyositis, Adult Type
Helse Stavanger HF

Recruiting

REBECCA-3 Study, Research on Breast Cancer Induced Chronic Conditions Supported by Causal Analysis of Multi-source Data (REBECCA-3)

Cancer Related Fatigue

Norway
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
Shenzhen Geno-Immune Medical Institute
The No.2 Clinical Hospital of the Ministry of Health

Recruiting

Engineered Dendritic Cell Vaccines for Multiple Myeloma

Multiple Myeloma or Plasmacytoma

China, Russian Federation
Peking Union Medical College Hospital

Recruiting

Clinical Characteristics and Analysis of Pituitary Complex and Rare Diseases

Pituitary Diseases

China
Hospital Universitari Vall d'Hebron Research Institute
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital and other collaborators

Recruiting

Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.

Hepatocellular Carcinoma | Portal Hypertension | Advanced Chronic Liver Disease

Spain
Hacettepe University

Not yet recruiting

Body Awareness and Mental Fatigue in Neck Pain

Mental Fatigue | Neck Pain | Mindfulness | Awareness

Turkey
Novo Nordisk A/S

Not yet recruiting

A Research Study of the Effect of Food on Etavopivat in Healthy Participants

Healthy Volunteers Sickle Cell Disease, Thalassemia

United States
University of Alberta
University of Calgary

Not yet recruiting

PAUSE: Sick Day Medication Management Mobile App Study (PAUSE)

Adverse Event | Chronic Condition
Institut Pasteur

Not yet recruiting

Genetic Determinants of the Antiviral Immune Response in Oceanian Populations (GEDIPOP)

Virus

New Caledonia
University of Thessaly

Not yet recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair (CoFA-TAAA)

Platelet Activation | Thoraco-abdominal Aortic Aneurysm Repair | Coagulation Factors Alterations

Greece
Post Graduate Institute of Medical Education and...
Indian Council of Medical Research

Not yet recruiting

Carvedilol + Simvastatin vs. Carvedilol Alone for Chronic Liver Disease and Cirrhotic Cardiomyopathy and Its Impact on Hepatic Decompensation and Survival; a Double-blind Randomized Controlled Trial (CIRROSTAT)

Decompensated Cirrhosis | Acute Kidney Injury | Cirrhosis, Liver | Left Ventricular Diastolic Dysfunction | Cirrhotic Cardiomyopathy
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Ovarian Cancer

United States, Germany
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Not yet recruiting

A Clinical Study of TQH2929 Injection in Treatment With Generalized Pustular Psoriasis (GPP)

Generalized Pustular Psoriasis

China
Savara Inc.

Not yet recruiting

Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).

Autoimmune Pulmonary Alveolar Proteinosis

United States
Duke University

Not yet recruiting

Prospective Registry of Ocular Melanoma Eye Plaque brachyTherapy Patients (PROMPT)

Ocular Melanoma
University Hospital of Ferrara
University of Milano Bicocca

Not yet recruiting

Metabolic Dysregulation as Biomarker of Frailty: Role of the Mitochondrial Dysfunction (FRAMITO)

Chronic Disease | Frailty | Aging | Mitochondrial Dysfunction
Tanta University

Not yet recruiting

External Oblique Intercostal Plane Block Versus Thoracic Paravertebral Block for Post Thoracotomy Pain

Post Thoracotomy Pain | Thoracic Paravertebral Block | External Oblique Intercostal Plane Block

Egypt
Shanghai Vitalgen BioPharma Co., Ltd.

Not yet recruiting

A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R09b in Severe AADC Deficiency

Aromatic L-amino Acid Decarboxylase Deficiency
Atrogi AB

Recruiting

The Attractive 2 Trial - Pharmacokinetics of ATR-258 Oral Capsule vs. Oral Solution Formulations in Healthy Volunteers (Attractive 2)

Type2diabetes

Sweden
MTI Biotech Inc
Vanderbilt University Medical Center

Not yet recruiting

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients (2-HOBA)

Alzheimer Disease | Mild Cognitive Impairment

United States

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