Search clinical trials for: Repeat dose

Total 22040 results

Oneness Biotech Co., Ltd.

Not yet recruiting

Evaluate Efficacy, Pharmacokinetics, and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Drexel University

Recruiting

The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery. (BET_RSE)

Nutraceuticals

United States
Chiesi Farmaceutici S.p.A.

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis

United Kingdom
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

Healthy Participants

United States, United Kingdom, Germany
Brexogen Inc.

Not yet recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Repeated-dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
Medical College of Wisconsin
University of Oklahoma

Recruiting

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage (TheoPHyLNNe)

Acute Kidney Injury | HIE

United States
Sustained Therapeutics Inc.

Recruiting

A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain

Chronic Pain

Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy

HIV-1

United States
Indonesia University

Not yet recruiting

Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

Arthroplasty Complications | Pregabalin | Analgetic | Celecoxib
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
Eli Lilly and Company

Recruiting

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Nonalcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

United States, Japan
UCB Biopharma SRL

Recruiting

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Atopic Dermatitis

United States
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Janssen, LP

Recruiting

An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge

Dengue

United States
UBP Greater China (Shanghai) Co., Ltd

Not yet recruiting

Evaluating Safety and Efficacy of Repeat Doses of UB-621in Adult Patients With Recurrent Genital Herpes

Recurrent Genital Herpes
Initiator Pharma

Not yet recruiting

A Phase II, Repeat Single Oral Dose Study of IPED2015 in Healthy Male Subjects With Erectile Dysfunction

Erectile Dysfunction
University of Rochester
National Cancer Institute (NCI)

Recruiting

Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT

Myeloma

United States
National Institute of Mental Health (NIMH)

Recruiting

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

Depression | Major Depressive Disorder | Healthy Volunteer

United States
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Juvenile Idiopathic Arthritis

Argentina, Bulgaria, Canada, Finland, France, Germany, Ireland, Italy, Russian Federation, Spain, United Kingdom
Boehringer Ingelheim

Active, not recruiting

A Study in Healthy People to Test How Well Repeated Doses of BI 3032950 Are Tolerated

Healthy

Belgium
Ology Bioservices
United States Department of Defense

Active, not recruiting

Single or Repeat Dose of G03-52-01 in Adult Subjects

Healthy | Botulinum Toxin

United States
Organon and Co

Completed

Corifollitropin Alfa in Participants Undergoing Repeated Controlled Ovarian Stimulation (COS) Cycles Using a Multiple Dose Gonadatropin Releasing Hormone (GnRH) Antagonist Protocol (Study 38825)(P05714) (Trust)

In Vitro Fertilization
Vejle Hospital
Hvidovre University Hospital

Active, not recruiting

Repeat Dose Steroid to Prevent Pain Relapse After Total Knee Arthroplasty in Patients With High Pain Response

Post Operative Pain, Acute

Denmark
GlaxoSmithKline

Terminated

A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants

Heart Failure

United Kingdom
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Healthy Subjects | Pharmacokinetics | Opioid Antagonist

United States
San Francisco Department of Public Health

Completed

Repeated-dose Behavioral Intervention to Reduce Opioid Overdose (REBOOT)

Opioid-Related Disorders | Drug Overdose

United States
GlaxoSmithKline

Completed

A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)

Pain, Inflammatory

United Kingdom, Germany, Poland
Garcia, Jose M., MD, PhD
Baylor College of Medicine; VA Office of Research and Development; AEterna Zentaris

Completed

Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia

Cancer Cachexia

United States
Kecioren Education and Training Hospital

Completed

Adductor Canal Block Versus Femoral Nerve Block With Repeated Bolus Doses Arthroplasty

Postoperative Pain | Functional Outcomes

Turkey
University Medical Center Groningen

Completed

Repeat CT Scans for Evaluation of Inter- and Intrafraction Motion and it's Effect on Radiotherapy Dose Distribution During Curative Radiotherapy for Pelvic Tumours (RACE)

Pelvic Tumor

Netherlands
Sanofi
Regeneron Pharmaceuticals

Completed

An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) (SKYPP)

Juvenile Idiopathic Arthritis

United States, Argentina, Canada, Chile, Czechia, Finland, France, Germany, Italy, Mexico, Netherlands, Poland, Russian Federation, Spain, United Kingdom
Bacoba AG
University Hospital, Basel, Switzerland; Swiss TPH, Basel, Switzerland

Active, not recruiting

Safety, Tolerability, and Pharmacokinetics of BAP5191 in Healthy Adults Following Topical Application of Repeat Doses

Healthy

Switzerland
Amgen

Completed

Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin

Healthy Volunteers

United States
Pfizer

Completed

Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia

Anorexia | Breast Cancer | Fatigue | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Cachexia | Non-small Cell Lung Cancer | Loss of Appetite

United States, Canada
Sanofi

Completed

A First-in-human Single and Repeated Dose Escalation Study of SAR442501 in Healthy Adults Subjects

Osteochondrodysplasia

United States
Algernon Pharmaceuticals
Centre for Human Drug Research, Netherlands

Active, not recruiting

Single and Repeat Doses of DMT in Healthy Subjects

Stroke

Netherlands
Sanofi

Completed

Tolerability, Pharmacokinetics and Pharmacodynamics of Ascending Single and Repeated Doses of SAR444336 in Healthy Adult Participants

Healthy Volunteer

Netherlands
Federal Teaching Hospital Abakaliki

Completed

Pre-operative Versus Post-operative Vaginal Cleansing With Chlorhexidine Solution in Prevention Post-Cesarean Section Infection

Post Cesarean Infectious Morbidity

Nigeria
Pfizer

Completed

Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.

Colorectal Cancer | Pancreatic Cancer | Cachexia | Non-Small-Cell Lung Cancer

United States
Indivior Inc.

Completed

Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder

Healthy Volunteer | Opioid-use Disorder

United States
San Francisco Department of Public Health

Completed

Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients (REBOOT)

Opioid-Related Disorders | Drug Overdose

United States
Suzhou Ribo Life Science Co. Ltd.

Completed

A Single and Repeated Dose Escalation of RBD1016 in Subjects With Chronic Hepatitis B Virus (HBV) Infection

Chronic Hepatitis b

China
Taisho Pharmaceutical Co., Ltd.

Completed

A Phase I Study of TS-142 in Healthy Participants (Repeated Doses)

Healthy Volunteer

Japan
GlaxoSmithKline

Completed

Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany
Sanofi

Completed

Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous and Subcutaneous Single and Repeated Doses of SAR441344 in Healthy Adult Subjects

Healthy Volunteers

United States
Araclon Biotech S.L.

Completed

Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD

Alzheimer Disease | Mild Cognitive Impairment

Spain, France, Sweden, Italy
Orion Corporation, Orion Pharma

Completed

Use of Buventol Easyhaler and Bufomix Easyhaler in Methacoline Challenge Testing (EASYRELIEF)

Asthma

Finland
Cliniques universitaires Saint-Luc- Université...

Completed

Effect of Repeated Injections of Higher Doses of Botulinum Toxin on Lower Limb of Spastic Hemiplegic Patients on Gait.

Stroke

Belgium
Heron Therapeutics

Active, not recruiting

Safety Study of Repeat Doses of SUSTOL in Adults

Chemotherapy-Induced Nausea and Vomiting (CINV)

United States
CSL Behring

Completed

Safety and Pharmacokinetics of Repeat Doses of CSL324 in Subjects With Hidradenitis Suppurativa and Palmoplantar Pustulosis

Hidradenitis Suppurativa | Palmoplantar Pustulosis

Denmark, Australia, Germany

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