Search clinical trials for: Reversal of Drug Resistance

Total 452809 results

Genelux Corporation
GOG Foundation

Recruiting

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Platinum-refractory Ovarian Cancer | Primary Peritoneal Cancer | High-grade Serous Ovarian Cancer | Endometrioid Ovarian Cancer | Ovarian Clear Cell Carcinoma

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Reversal of Lipid-Induced Insulin Resistance

Insulin Resistance | NAFLD

United States
University of Texas Southwestern Medical Center

Completed

Effects of Hyperuricemia Reversal on Features of the Metabolic Syndrome

Gout

United States
Washington University School of Medicine

Completed

FMT for Multidrug Resistant Organism Reversal

Infection With Multi-drug Resistant Organisms
National Cancer Institute (NCI)

Completed

Tariquidar and Docetaxel to Treat Patients With Lung, Ovarian, Renal and Cervical Cancer

Lung Neoplasms | Ovarian Neoplasms | Cervix Neoplasms | Renal Neoplasms

United States
National Cancer Institute (NCI)

Completed

Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer

Adrenal Cortex Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Study of Combination Chemotherapy and Surgical Resection in the Treatment of Adrenocortical Carcinoma: Continuous Infusion Doxorubicin, Vincristine and Etoposide With Daily Mitotane Before and After Surgical Resection

Adrenal Cortical Carcinoma

United States
National Cancer Institute (NCI)

Completed

Vinorelbine and XR9576 to Treat Cancer

Cancer | Breast Cancer | Ovarian Cancer | Lung Cancer

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

Lymphoma | Breast Cancer | Neoplasm Metastasis | Ovarian Cancer | Kidney Neoplasm

United States
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

The Ameliorative Effects of GLP-1RA on Diabetic Cardiac Autonomatic Neuropathy

Type 2 Diabetes | Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)
Stemline Therapeutics, Inc.

Not yet recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Acute Myeloid Leukemia

United States
Guangdong Provincial People's Hospital

Not yet recruiting

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Acute Myeloid Leukemia

China
The Swedish School of Sport and Health Sciences
Karolinska Institutet; Sahlgrenska University Hospital, Sweden; Prostate Cancer... and other collaborators

Recruiting

Training for Men Undergoing Androgen Deprivation Therapy. (ADT-train)

Prostate Cancer

Sweden
Pfizer

Recruiting

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination (LTbR)

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Urothelial Cancer | Advanced or Metastatic Solid Tumors

United States, Puerto Rico
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

A Phase 2 Study to Evaluate the Efficacy of the Combination of Cemiplimab and Cetuximab Prior to Salvage Surgery in Patients With Locally Recurrent (Stage 3-5) OCSCC

Locally Recurrent OCSCC

United States
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancer | CRC | Metastatic Pancreatic Ductal Adenocarcinoma | PDAC

United States
Hunan Province Tumor Hospital
Hunan Cancer Hospital

Recruiting

Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases (EPIC)

Non-Small Cell Lung Cancer

China
University of Regina

Recruiting

Strategic Ingestion of Creatine Supplementation and Resistance Training in Trained Young Adults

Muscle | Strength

Canada
Clinical Hospital Centre Zagreb

Not yet recruiting

Therapeutic Options for CRAB (TheraCRAB)

Infections, Bacterial | Sepsis Bacterial
University of Illinois at Urbana-Champaign

Not yet recruiting

Nutritional Intervention for Sustaining Health (NURISH) Trial

Cognitive Change | Diet, Healthy | Metabolic Syndrome, Protection Against
Beijing Tongren Hospital
The First Affiliated Hospital with Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Reversal of Neuromuscular Blockade

China
Maastricht University Medical Center

Not yet recruiting

Effects of Ingesting Multiple Boluses of Collagen on Muscle & Skin Connective Protein Synthesis in Vivo in Humans (CODIAK)

Muscle Protein Synthesis

Netherlands
Daping Hospital and the Research Institute of Surgery...

Not yet recruiting

Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Ovarian Cancer

United States, Germany
University Hospital, Brest

Not yet recruiting

Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii (DDBIOS)

Pneumocystis Pneumonia

France
Octapharma

Not yet recruiting

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Significant Bleeding Risk | Vitamin K-Dependent Coagulation Defect
Central South University

Not yet recruiting

Investigating the Insulin Resistance in Individuals With Type 2 Diabetes

Type 2 Diabetes

China
Merck Sharp & Dohme LLC

Not yet recruiting

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Metastatic Breast Cancer
Region Skane
The George Institute for Global Health, Australia

Not yet recruiting

International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER)

Stroke | Intraventricular Hemorrhage | Cerebrovascular Disease | Intracerebral Hemorrhage | Intracerebral Haemorrhage

Australia, Sweden
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Georgiamune Inc

Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Solid Tumor | Melanoma Stage IV

United States
University of South Carolina

Recruiting

Resistance Exercise and Creatine in Colorectal Cancer

Colorectal Cancer

United States
University of Udine

Recruiting

Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy (ENDOmiRNA)

Endometriosis

Italy
Beneficência Portuguesa de São Paulo
Ministry of Health, Brazil

Not yet recruiting

Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)

Central Nervous System Infections
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
TOLREMO therapeutics AG

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors (TT-CSP-001)

Cancer | Adult Solid Tumor | Advanced Solid Tumor | Adult Disease

Spain, Switzerland
Maastricht University Medical Center
Cargill

Recruiting

Plant Protein Blend and Milk Protein Supplements in Older Individuals (Blend-D2O)

Sarcopenia | Skeletal Muscle Atrophy | Protein Malnutrition

Netherlands
Assiut University

Not yet recruiting

Clinical and Laboratory Evaluation of Antifungal Resistance in Tinea Capitis

Fungal Resistance
Maastricht University Medical Center

Not yet recruiting

Effects of Ketone Monoesters on Brain Function

Cerebral Blood Flow | Cognitive Performance | Appetite Control | Brain Vascular Function | Brain Insulin Sensitivity

Netherlands
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients

Obesity | Atypical Endometrial Hyperplasia | Progesterone Resistance

China
Erasme University Hospital

Not yet recruiting

Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study (Memori³)

Alzheimer Disease | Mild Cognitive Impairment
Abderrahmane Mami Hospital

Recruiting

Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units (NOSOREA3)

Critical Illness | Cross Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection

Tunisia
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
University of Aarhus
Aarhus University Hospital; University of Copenhagen

Not yet recruiting

Resistance Training and Corticospinal Excitability in Multiple Sclerosis (NEXIMS)

Multiple Sclerosis
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
Assiut University

Not yet recruiting

Association Between Triglycerides Glucose Ratio With HOMA -IR as Indicators of Insulin Resistance in Obese Adults

Insulin Resistance
University Hospital, Montpellier

Not yet recruiting

Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients (KREBSome-IRC)

Metabolic Syndrome | Dialysis; Complications

France

Search clinical trials for: Reversal of Drug Resistance

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