Search clinical trials for: SMAD4 methylation

Total 422 results

Trakya University

Recruiting

SMAD4 Methylation and Expression Levels in Non-melanocytic Skin Cancers; SMAD4 Protein Positivity

Basal Cell Carcinoma

Turkey
Regional Hospital Holstebro

Completed

The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals

Healthy

Denmark
Memorial Sloan Kettering Cancer Center

Recruiting

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk

BRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditions

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Terminated

High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer

United States
University of Roma La Sapienza
Azienda Ospedaliero, Universitaria Pisana

Unknown

Mutation of K-RAS, CDKN2A, SMAD4 and TP53 in Pancreatic Cancer: Role of Liquid Biopsy in Preoperative Diagnosis

Pancreatic Cancer

Italy, Ireland
Hospices Civils de Lyon

Completed

Genotype Expression and Phenotype of Endothelial Cells, Carrying an ACVRL1, ENG or SMAD4 Mutation, in Response to BMP9 for the Identification of New Therapeutic Targets in Hereditary Haemorrhagic Telangiectasia (CAERO)

Hereditary Haemorrhagic Telangiectasia

France
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom
Changhai Hospital

Not yet recruiting

Urine DNA Methylation Detection for Hematuria Evaluation

Bladder Cancer | Urothelial Carcinoma | Ureter Cancer | Hematuria | Renal Pelvis Cancer

China
University of Rome G. Marconi
University of Bologna; University of the Italian Switzerland

Not yet recruiting

Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health (MOTHERS)

Stress | Insomnia | Postpartum Depression

Italy
Obstetrics & Gynecology Hospital of Fudan University
Peking Union Medical College Hospital; First Affiliated Hospital of Xinjiang... and other collaborators

Not yet recruiting

Role of Methylation Test Triage in HPV Positive Women (MTTRIHPW)

Precancerous Cervical Lesion

China
Shanghai Chest Hospital

Recruiting

Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan

Carcinoma | Non-small Cell Lung Cancer

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Federico II University; Istituto Auxologico Italiano; Università degli Studi...

Recruiting

Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks

Beckwith-Wiedemann Syndrome

Italy
City of Hope Medical Center

Recruiting

Stage II/III Colorectal Cancer Recurrence (CENSURE)

Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Recurrent

Spain, United States, China
Mayo Clinic

Recruiting

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Central Arkansas Veterans Healthcare System
United States Department of Defense; University of Arkansas

Recruiting

DNA Methylation Markers in Veterans Exposed to Open Burn Pits

Open Burn Pit Exposure

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH)

Recruiting

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) (BASH OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma

United States
Pennington Biomedical Research Center

Recruiting

Diet-Induced Changes in GEnetic Material (DIG 'EM)

Body Weight | Diet, Healthy | Metabolic Disturbance

United States
Meyer Children's Hospital IRCCS
Careggi Hospital; University of Florence

Not yet recruiting

The Epigenomic Signature of Eosinophilic Granulomatosis With Polyangiitis (EPI-EGPA)

Eosinophilic Granulomatosis With Polyangiitis
Shanghai Weihe Medical Laboratory Co., Ltd.
Peking University People's Hospital

Recruiting

a PROspective Case Control Study to Develop and Validate a Blood Test FOr mUlti-caNcers Early Detection（PROFOUND） (PROFOUND)

Cancer

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

DNA Methylation Combined With Artificial Intelligence Imaging to Identify Lung Nodules (MAGIC)

Lung Cancer Diagnosis

China
Singlera Genomics Inc.
Shanghai Zhongshan Hospital

Recruiting

Clinical Research on Dynamic Monitoring MRD Via Plasma ctDNA After Systemic Therapy of Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Sir Run Run Shaw Hospital

Recruiting

Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer (cmPAT)

Colorectal Cancer

China
Sun Yat-sen University
The First Affiliated Hospital of Anhui Medical University; Peking University... and other collaborators

Recruiting

PaCIFiC-CUP Classifies Cancer of Unknown Primary

Unknown Primary Tumors | DNA Methylation

China
Air Force Military Medical University, China

Recruiting

A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles

Bile Duct Diseases | Bile Duct Neoplasms | Jaundice, Obstructive

China
Dartmouth-Hitchcock Medical Center

Recruiting

Immune Profiling for Cancer Immunotherapy Response

Cancer | Hematologic Malignancy | Blood Cancer | Tumor, Solid

United States
Hospital Clinico Universitario de Santiago
Hospital Arquitecto Marcide

Not yet recruiting

Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer (NUTOBREST)

Obesity | Breast Cancer | Weight Change, Body | Epigenetic Disorder
Air Force Military Medical University, China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; The First Affiliated... and other collaborators

Recruiting

Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreas Cancer | Liver Cancer | Esophagus Cancer | Cancer Diagnosis | LungCancer

China
Weill Medical College of Cornell University
National Cancer Institute (NCI); University of Sao Paulo; H. Lee Moffitt Cancer... and other collaborators

Recruiting

Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries

HIV Infections | Cervix Cancer | HPV Infection | Cervical High Grade Squamous Intraepithelial Lesion

Brazil, Mexico
Xijing Hospital

Recruiting

A Population-based, Multicenter Cohort Study of Combined Screening for Gastrointestinal Tumors

Digestive Disease

China
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer

Stage III Colorectal Cancer | High-risk Stage II Colorectal Cancer | Circulating Tumor DNA Methylation

China
RenJi Hospital

Not yet recruiting

Multiomics Study of Fibrosis Factors After Liver Transplantation and Exploration of Fibrosis Methylation Biomarkers

Liver Fibrosis

China
Mahidol University

Not yet recruiting

Effects of Kimchi Supplementation on Gut Microbiota, DNA Methylation and Serum Proteomes

Obesity

Thailand
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer

Non-metastatic Colorectal Cancer | Circulating Tumor DNA Methylation

China
Queen Mary University of London
National Cancer Institute (NCI)

Recruiting

HPV Self-testing in Transgender Individuals (Self-TI)

HPV Infection

United Kingdom
Singlera Genomics Inc.
Beijing Friendship Hospital

Recruiting

Study on Early Auxiliary Diagnosis and Postoperative Recurrence Monitoring of Breast Cancer

Breast Cancer

China
Assiut University

Recruiting

Immunohistochemical Evaluation of DNA Methylation and Histone Modification in H. Pylori Associated Gastric Carcinoma

Gastric Carcinoma

Egypt
Dr. Christopher Mueller
Canadian Institutes of Health Research (CIHR); Queen's University

Recruiting

Using a Blood Test to Monitor Metastatic Breast Cancer Treatment (BEACON)

Metastatic Breast Cancer

Canada
Lei Li

Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis | ROMA Index

China
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
Ulla Kampmann Opstrup
Per Ovesen, Professor Dept. of Obsteterics, Aarhus University Hospital; Jens... and other collaborators

Recruiting

PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus (PREPARE CHILD)

Weight Loss | Pregnancy Related | Body Composition | Overweight and Obesity | Child Nutrition Sciences

Denmark
Centre Hospitalier Universitaire, Amiens

Recruiting

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity (EPSACO)

Biomarkers | Epigenetics | Oral Squamous Cell Carcinoma | DNA Methylation | Saliva | Maxillo-facial Surgery

France
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University of Aberdeen

Not yet recruiting

Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children (MINUTES)

Stunting | Nutrition | Epigenetics | DNA Methylation | Development, Child
Chiayi Christian Hospital

Recruiting

The Application of Serum DNA Methylation for Patients With HCC

Hepatocellular Carcinoma

Taiwan
Zhaoshen Li

Recruiting

Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples

Pancreatic Neoplasms | DNA Methylation | Proteome

China
University of Aarhus
Randers Regional Hospital

Recruiting

Screening Triage and Risk Stratification (I-share)

Cervix Cancer | Postmenopausal Women | HPV Testing

Denmark
National University of Singapore
Agency for Science, Technology and Research; AMILI Pte. Ltd.

Recruiting

Does Alpha-ketoglutarate Supplementation Lower BiologicaL agE in Middle- Aged Adults? (ABLE)

Aging

Singapore
Qiu Lugui
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

Assessment of Early Detection and Prognosis Based on cfDNA Methylation in Multiple Myeloma

Multiple Myeloma

China
Wuhan Ammunition Life-tech Co., Ltd

Recruiting

Clinical Study of Pan-cancer DNA Methylation Test in Plasma

Cancer

China
Zhujiang Hospital
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors (ASCEND-BRAIN)

Intracranial Tumors

China
Wuhan Ammunition Life-tech Co., Ltd
Wuhan University

Not yet recruiting

GNB4 and Riplet Gene Methylation Combined Detection Kit (Fluorescence PCR Method)

Hepatocellular Carcinoma

Search clinical trials for: SMAD4 methylation

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