Search clinical trials for: Secondary bile acid malabsorption

Total 32592 results

Imperial College Healthcare NHS Trust

Completed

Obeticholic Acid in Bile Acid Diarrhoea (OBADIAH1)

Primary Bile Acid Malabsorption | Secondary Bile Acid Malabsorption | Chronic Diarrhoea

United Kingdom
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Montana State University

Recruiting

Impact of Foods on Bile Acids, Metabolites, and Inflammation

Inflammation | Hyperlipidemias | Hypertriglyceridemia | Metabolic Disease | Bile Acid Malabsorption | Lipid Metabolism Disorder

United States
Stanford University

Recruiting

The Role of Secondary Bile Acids in Intestinal Inflammation

Ulcerative Colitis | Pouchitis

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Albireo

Completed

Double-blind, Randomised Study of A3384 in BAM/BAD

Bile Acid Malabsorption

Sweden, United Kingdom
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Modulation of Secondary Bile Acids Through the Intestinal Microbiota After Consumption of a High-protein Diet.

Healthy

Mexico
Michael Camilleri, MD
NGM Biopharmaceuticals, Inc

Completed

Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)

Irritable Bowel Syndrome With Diarrhea | Bile Acid Malabsorption | Chronic Diarrhea | Functional Diarrhea | Bile Acid Diarrhea | Bile Acid Malabsorption Syndrome Type II

United States
University of Pittsburgh

Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

Multiple Sclerosis | Diabetes Mellitus | Chronic Kidney Diseases | Gastritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Hepatitis | Inflammatory Bowel Diseases | Dyslipidemias | Chronic Disease | Celiac Disease | Cholecystitis | Crohn Disease | Cystic Fibrosis | Chronic Pancreatitis | NASH - Nonalcoholic... and other conditions

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

A Study of Colesevelam in Fecal Incontinence

Fecal Incontinence | Bile Acid Malabsorption

United States
Lars Kristian Munck
Pierre and Marie Curie University

Completed

Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea (SINBAD)

Bile Acid Malabsorption | Chronic Diarrhea

Denmark
Filip Krag Knop
Herlev and Gentofte Hospital

Completed

Treatment of Bile Acid Malabsorption With Liraglutide (BAM-LIRA)

Bile Acid Malabsorption

Denmark
Zealand University Hospital

Completed

Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy (BACH)

Cholelithiasis | Bile Acid Malabsorption

Denmark
University of Aarhus
GE Healthcare; Danish Cancer Society

Completed

The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon

Diarrhea | Colon Adenocarcinoma

Denmark
Allergan

Completed

Eluxadoline Bile Acid Malabsorption (BAM) Study

Irritable Bowel Syndrome With Diarrhea

United States
Novartis Pharmaceuticals

Completed

To Assess Safety, Tolerability and Efficacy of LJN452 in Patients With Primary Bile Acid Diarrhea.

Primary Bile Acid Diarrhea

United States, United Kingdom
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Irritable Bowel Syndrome With Diarrhea | Bile Acid Malabsorption | Chronic Diarrhea

United States
University of Oklahoma
OU Medical Center

Completed

Compassionate Use of Omegaven in Children

Infant, Premature, Diseases | Cholestasis | Gastroschisis | Intestinal Atresia | Short Bowel Syndrome | Cholestasis of Parenteral Nutrition | Total Parenteral Nutrition-induced Cholestasis

United States
Lars Kristian Munck

Completed

Validation of Stimulated ∆FGF19 for Diagnosing Bile Acid Diarrhoea (VABAD)

Bile Acid Malabsorption

Denmark
Royal Marsden NHS Foundation Trust

Completed

The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms" (FOCCUS)

Cancer

United Kingdom
University Hospital, Gentofte, Copenhagen

Completed

Bileacid Malabsorption and GLP-1 Secretion

Bileacid Malabsorption

Denmark
Florian Beigel

Terminated

Colesevelam for the Treatment of Bile Acid Malabsorption in Patients With Crohn's Disease (COBAM)

Crohns Disease | Bile Acid Malabsorption

Germany
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)? (welchol)

Irritable Bowel Syndrome | Diarrhea

United States
Institut Investigacio Sanitaria Pere Virgili

Not yet recruiting

Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs (TREV)

Obesity
Eyestem Research Pvt. Ltd.

Not yet recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease
Ipsen

Not yet recruiting

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid. (ELSPIRE)

Primary Biliary Cholangitis
Prehospital Center, Region Zealand

Not yet recruiting

Primary or Secondary Drowning (DROWN_COD)

Drowning | Drowning; Anoxia | Drowning, Near | Drowning; Asphyxia | Drowning or Immersion of Unknown Intent | Drowning and Submersion, Undetermined Intent | Drowning and Submersion While in Bath-Tub | Drowning and Submersion While in Natural Water | Drowning and Submersion Due to Sailboat Sinking | Drowning... and other conditions

Denmark
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Recruiting

Evaluation of a Genetically Determined Personalized Approach in Prescribing Biologically Active Substances in Patients With Elevated Blood Homocysteine Levels. (PERBIO-HC)

Hyperhomocysteinemia

Russian Federation
Sanjiv Harpavat
Baylor College of Medicine

Not yet recruiting

Tolerability of Enteral NAC in Infants

Biliary Atresia
University of Manchester

Not yet recruiting

The 8x5 Diet for Bile Acid Diarrhoea: A Feasibility Randomised Controlled Trial

Bile Acid Diarrhea

United Kingdom
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis (ABRICO)

Ulcerative Colitis

France
St. Boniface Hospital

Not yet recruiting

Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation. (MYSTIC)

Fontan Circulation
POLYSAN Scientific & Technological Pharmaceutical...

Recruiting

Comparative Study of REMAXA®, Enteric-coated Tablets and REMAXOL®, Solution for Infusions, in Intrahepatic Cholestasis

Cholestasis, Intrahepatic

Russian Federation
Jun Wang

Recruiting

Thymosin Alpha-1 for irAE Secondary to ICIs

IrAE

China
Han Ying

Recruiting

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Case Comprehensive Cancer Center
National Institutes of Health (NIH)

Not yet recruiting

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Prostate Cancer | Malignant Neoplasm of Prostate | Secondary Malignant Neoplasm of Prostate

United States
Region Stockholm
Amgen

Not yet recruiting

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Acute Metabolic Effects of Evolocumab and Atorvastatin
Intercept Pharmaceuticals

Not yet recruiting

Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy

Biliary Atresia
Air Force Military Medical University, China

Recruiting

A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles

Bile Duct Diseases | Bile Duct Neoplasms | Jaundice, Obstructive

China
National University of Malaysia

Recruiting

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

Pancreatic Cancer | Cholangitis | Choledocholithiasis | Choledochal Cyst

Malaysia
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
CymaBay Therapeutics, Inc.

Recruiting

IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA) (IDEAL)

Primary Biliary Cholangitis

United States
Xijing Hospital of Digestive Diseases

Recruiting

Application of Serum Bile Acid Profile in the Diagnosis of Gastric Cancer

Gastric Cancer

China
Medical University of Warsaw
National Science Centre, Poland

Recruiting

S-adenosylmethionine (SAMe) in Patients With Primary Sclerosing Cholangitis (PSC)

Primary Sclerosing Cholangitis (PSC)

Poland
Mayo Clinic

Recruiting

A Study of Hemp Hull WFI for IBS Diarrhea

Irritable Bowel Syndrome-bile Acid Diarrhea

United States
Entrinsic Bioscience Inc.

Not yet recruiting

Evaluation of a Novel Amino Acid Based Moisturizing Cream as Part of the Daily Standard Skincare Regimen Recommended During Radiation Therapy

Erythema | Radiation Therapy, Secondary Skin Reactions

United States
University of Illinois at Urbana-Champaign

Recruiting

Persea Americana for Total Health (PATH)-2 (PATH-2)

Overweight and Obesity

United States
Children's Hospital of Fudan University

Recruiting

Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy

Cholangitis | Anti-Bacterial Agents | Biliary Atresia

China

Search clinical trials for: Secondary bile acid malabsorption

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