Search clinical trials for: Secondary iron overload

Total 5932 results

City of Hope Medical Center

Terminated

Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Iron Overload | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
Genzyme, a Sanofi Company

Completed

Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia

Beta-Thalassemia

United States
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Weill Medical College of Cornell University

Unknown

Iron Balance Study of Deferasirox, Deferoxamine and the Combination of Both

Thalassemia

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
Cornell University

Recruiting

Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption (FeMicrobiome)

Iron Overload | Anemia, Iron Deficiency

United States
Azienda Ospedaliero-Universitaria di Modena

Recruiting

"Iron Overload and Endocrinological Diseases"

Iron Overload | Hemochromatosis | Thalassemia Major | Thalassemia Intermedia | Endocrinopathy

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Leflunomide for Idiopathic Pulmonary Hemosiderosis in Children (Lef for IPH)

Idiopathic Pulmonary Hemosiderosis | Leflunomide

China
Qianfoshan Hospital

Recruiting

Analysis of the Effect of Iron Supplements on Iron Deficiency Anemia in Pregnancy

Iron Deficiency Anemia of Pregnancy | Iron Storage Disease

China
Yonsei University

Not yet recruiting

Lazertinib+Pemetrexed/Carboplatin in Patients With EGFR Sensitizing Mutation Positive Recurrent or Metastatic Non-Small Cell Lung Cancer Failed to Prior Lazertinib (LUCAS)

Non-small Cell Lung Cancer

Korea, Republic of
Assiut University

Not yet recruiting

NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

Thalassemia Major
Ramsay Générale de Santé
European Clinical Trial Experts Network

Not yet recruiting

Iron Deposits in the Pancreas by MRI Method of Dialysis Patients With Hemosiderosis Iatrogenic (ERDFP) (ERDFP)

Dialysis | Iron Deposition | Iatrogenic Hemosiderosis

France
Assiut University

Not yet recruiting

Oxidative Stress and Iron Overload in Patient With Abnormal Haemoglobinopathy

Oxidative Stress in Patient With Haemoglobinopathy and Affect it of Endocrine System
Hangzhou Zede Pharma-Tech Co., Ltd.

Recruiting

Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients

Iron Overload | Thalassemia

China
Swiss Federal Institute of Technology
Mahidol University

Not yet recruiting

Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults With Thalassemia

Iron Overload | Thalassemia

Thailand
University of Wisconsin, Madison
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Recruiting

Fully Automated High-Throughput Quantitative MRI of the Liver

Healthy | Iron Overload | Liver Fat

United States
University Hospital, Bordeaux

Recruiting

Iron Chelation in the Prevention of Secondary Degeneration After Stroke (CHEL-IC)

Stroke

France
Federal Research Institute of Pediatric Hematology...

Recruiting

MRI T2* Mapping of Myocardium, Liver, Pancreas and Pituitary Gland

Iron Overload

Russian Federation
Rennes University Hospital

Recruiting

Impact of Transferrin Saturation Guided Maintenance Treatment on Quality of Life in HFE Haemochromatosis (Quali-SAT)

Haemochromatosis

France
University of Pisa
IRCCS Burlo Garofolo; University of Genova

Recruiting

Risk Factors and Measures to Prevent Liver and Pancreas Complications in Pediatric Patients After HSCT

Iron Overload

Italy
University Health Network, Toronto

Recruiting

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (TICATS)

Thalassemia Major

Canada
Weill Medical College of Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Columbia... and other collaborators

Recruiting

Quantitative Susceptibility Mapping (QSM) to Guide Iron Chelating Therapy

MRI Scans

United States
Perspectum

Recruiting

Repeatability and Reproducibility of Multiparametric MRI

Liver Diseases | Cirrhosis | Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Hemochromatosis | Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis | Primary Biliary Cirrhosis | Viral Hepatitis

Netherlands, United Kingdom
M.D. Anderson Cancer Center

Recruiting

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome and other conditions

United States
CHRISTUS Health

Completed

Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness (PAMS)

Acute Mountain Sickness | AMS

United States
Novartis Pharmaceuticals

Completed

Survey to Assess Physicians' Knowledge of Exjade Posology and Biological Monitoring Recommendations as Described in the Educational Materials

Chronic Iron Overload

Switzerland
National Institutes of Health Clinical Center (CC)

Active, not recruiting

Treatment of Hemochromatosis

Hemochromatosis

United States
University of Wisconsin, Madison
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Stanford...

Completed

MRI QSM Imaging for Iron Overload

Iron Overload | Hemochromatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiac Function in Patients With Hereditary Hemochromatosis

Hereditary Hemochromatosis

United States
University of Wisconsin, Madison
Johns Hopkins University; National Institute of Diabetes and Digestive and... and other collaborators

Enrolling by invitation

Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron Content

Iron Overload | Hemosiderosis | Hemochromatosis

United States
Prothya Biosolutions

Active, not recruiting

Apotransferrin in Atransferrinemia

Congenital Atransferrinemia

Spain, Germany, Italy
Haukeland University Hospital
Novartis

Withdrawn

Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic Syndrome (DefeHEMY)

Myelodysplastic Syndromes | Hemochromatosis

Norway
Novartis Pharmaceuticals

Completed

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Transfusion-dependent Anemia

Egypt, Hungary, Turkey, United States, Bulgaria, Italy, Belgium, Russian Federation, Philippines, France, Malaysia, India, Oman, Panama, Lebanon, Thailand, Tunisia
Chiesi Canada Corp

Completed

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children (START)

Iron Overload | Beta Thalassemia Major Anemia

Egypt, Indonesia
State University of New York at Buffalo
The Callum McKeefery and Nikki Albano McKeefery Pediatric Division of Genetics...

Completed

Natural History Study of FDXR Mutation-related Mitochondriopathy

Mitochondrial Diseases | Optic Atrophy | Neurodegenerative Disease, Hereditary

United States
Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Ethnic Differences in Iron Absorption (FeGenes) (FeGenes)

Iron Overload | Anemia, Iron Deficiency

United States
Boston Children's Hospital
Novartis

Completed

Pilot Study for Patients With Poor Response to Deferasirox

Sickle Cell Disease | Thalassemia Major | Transfusion-dependent Hemachromatosis

United States
ApoPharma

Terminated

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Iron Overload | Sickle Cell Disease | Other Anemias

United States, United Kingdom, Egypt, Canada, Saudi Arabia
Novartis Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Hereditary Hemochromatosis

Belgium, France, Russian Federation, Romania, Slovakia, Spain, Switzerland
The University of Texas Health Science Center at...
Abfero Pharmaceuticals, Inc

Suspended

Safety of SP-420 in the Treatment of Transfusional Iron Overload

Iron Overload

United States
Hangzhou Zede Pharma-Tech Co., Ltd.

Completed

Long-term Clinical Study of CN128 in Thalassemia Patients

Iron Overload | Thalassemia

China
Children's Hospital Los Angeles
Novartis Pharmaceuticals

Completed

Changes in Pituitary Iron and Volume With Deferasirox

Iron Overload

United States
University of Utah

Completed

Novel Imaging Markers in SPMS

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Secondary Progressive Multiple Sclerosis

United States
Bond Biosciences

Terminated

A Study to Evaluate BBI-001 in Hereditary Haemochromatosis (HH) Patients and Iron Deficient Volunteers

Hereditary Hemochromatosis

Australia
Protagonist Therapeutics, Inc.

Completed

PTG-300 in Subjects With Hereditary Hemochromatosis

Hereditary Hemochromatosis

United States, Canada
Rennes University Hospital
Ministry of Health, France

Completed

Quantification of Liver Iron Overload and Steatosis Using Magnetic Resonance Imaging (SURFER)

Hepatitis B | Hepatitis C | Iron Overload | Metabolic Syndrome X | Alcohol Abuse

France, Spain
Rennes University Hospital

Completed

Evaluation of Body Iron Stores in Overweight Healthy Volunteers (FERNORM)

Overweight | Healthy Volunteers

France
Rennes University Hospital
Ministry of Health, France

Completed

Phlebotomy and Lifestyle and Diet Advices vs Lifestyle and Diet Advices Only in Patients With Dysmetabolic Liversiderosis (SAIGNEES)

Liver Cirrhosis | Iron Overload

France
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Implications for Quality of Life and Quality of Care in Patients With Hereditary Haemochromatosis

Hereditary Haemochromatosis

Belgium

Search clinical trials for: Secondary iron overload

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