Search clinical trials for: Severe Ulcerative colitis

Total 10129 results

Pfizer

Not yet recruiting

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis (ENDEAVOUR-UC)

Colitis, Ulcerative
Gilead Sciences

Recruiting

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis (SWIFT)

Ulcerative Colitis

United States
Assiut University

Not yet recruiting

Value Of ACE Index (Albumin, CRP And Endoscopy) In Predicting Intra Venous Steroid Response In Acute Severe Ulcerative Colitis In Assiut University Hospitals

Early Detection of Complication of Ulcerative Colitis
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR Jr)

Colitis, Ulcerative

Belgium, United States, China, Denmark, Japan, Italy, Turkey, Poland
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, France, Hungary, Korea, Republic of, Belgium, Japan, Germany, Canada, Italy, Poland, Czechia, Denmark, Greece, Norway, Romania, Slovakia, United Kingdom
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)

Ulcerative Colitis

United States
AnaptysBio, Inc.

Recruiting

A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Ulcerative Colitis (ROSETTA)

Ulcerative Colitis

United States, Georgia
AltruBio Inc.

Recruiting

Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics

Ulcerative Colitis

United States, Canada
Bristol-Myers Squibb

Recruiting

A Post-Marketing Surveillance Study to Assess Safety of Ozanimod in Patients With Moderate to Severe Active UC in Korea

Ulcerative Colitis

Korea, Republic of
Merck Sharp & Dohme LLC
PPD, Part of Thermo Fisher Scientific

Recruiting

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

Ulcerative Colitis

United States, Israel, Japan, Korea, Republic of, Switzerland, Chile
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis (ANTHEM-UC)

Colitis, Ulcerative

Korea, Republic of, Australia, United States, Czechia, Malaysia, Turkey, Japan, Belgium, Hungary, Canada, Italy, Spain, China, Poland, United Kingdom, Germany, Brazil, France, Argentina, Romania, India
Gilead Sciences

Recruiting

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis (PALEKONA)

Ulcerative Colitis

United States, Australia, United Kingdom, Korea, Republic of, Japan, Canada, Switzerland
Xijing Hospital of Digestive Diseases

Not yet recruiting

Autologous Platelet-rich Plasma (PRP) and Thrombin Coagulum for the Topical Treatment of Rectal Mucosal Ulcers

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe | Rectal Ulcer

China
Curacle Co., Ltd.

Not yet recruiting

Phase 2 Study of CU104 in Moderate-Severe Ulcerative Colitis (UC)

Ulcerative Colitis
Berinstein, Jeffrey

Recruiting

A Trial for Acute Severe Ulcerative Colitis

Ulcerative Colitis Acute

United States
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan

Ulcerative Colitis

Japan
Landos Biopharma Inc.

Recruiting

Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, Italy, Poland
Eli Lilly and Company

Recruiting

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis (SHINE-2)

Ulcerative Colitis

Canada, United States, Japan, Belgium, Israel, Portugal, Korea, Republic of, France, Australia, Italy, Netherlands, Poland, Germany, United Kingdom
AbbVie

Recruiting

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Ulcerative Colitis

United States, Japan, Taiwan, Spain, Korea, Republic of, Bulgaria, Italy, Poland, France, United Kingdom, Greece, New Zealand, Australia, Belgium, Israel, Hungary
Eli Lilly and Company

Recruiting

A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT-URGE)

Ulcerative Colitis | Ulcerative Colitis Chronic

United States, Poland, United Kingdom, Czechia, Hungary, Italy, France, Canada, Belgium, Slovakia, Austria, Germany
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Recruiting

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States
IRCCS San Raffaele

Recruiting

Comparison Between Bowel Ultrasound-based Treat to Target Versus Routine Treat to Target Strategies in Ulcerative Colitis

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe

Italy
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Colitis Ulcerative

Argentina, Korea, Republic of, Mexico, United States, Canada, Chile, Japan, Puerto Rico, South Africa, Taiwan, Turkey
Amgen

Recruiting

Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Germany, Japan, Denmark, Romania, Argentina, Bulgaria, Hungary, Korea, Republic of, Mexico, Poland, Switzerland, Turkey
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease

Crohn Disease | Colitis, Ulcerative

United States, Hungary, Poland, Czechia, Japan, Belgium, Spain, Bulgaria, France, Italy, Slovakia, Austria
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Ulcerative Colitis

China, Taiwan
Morphic Therapeutic, Inc

Recruiting

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC (EMERALD-2)

Inflammatory Bowel Diseases | Colitis, Ulcerative

United States, Australia
AbbVie

Recruiting

Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, France, Poland
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

A Study to Test the Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease (RELIEVE UCCD)

Crohn Disease | Colitis, Ulcerative

United States, Bulgaria, Hungary, Poland, Spain, Belgium, Czechia, France, Italy, Japan, Norway, Slovakia, Germany, Canada, Ukraine, United Kingdom, Israel, Serbia
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice (PROFUNDUS)

Ulcerative Colitis

Germany, Russian Federation, United Arab Emirates, United Kingdom, Australia, Ireland, Argentina, Canada, Kuwait, Israel, Portugal, Czechia, France, Greece, Italy
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

Phase II Study of Hemay005 in Patients With Active Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

China
Central Hospital, Nancy, France

Recruiting

A Study to Evaluate Biomarkers in Moderate to Severe Ulcerative Colitis (UC) Patients Treated With Different Targeted Therapies (ImmUniverse)

Inflammatory Bowel Diseases | Ulcerative Colitis

France
Takeda

Recruiting

A Study of Vedolizumab SC Given to Adults With Moderate to Severe Ulcerative Colitis or Crohn's Disease in South Korea

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease (IBD)

Korea, Republic of
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Evaluate IBI112 in the Treatment of Moderate to Severe Active Ulcerative Colitis

Ulcerative Colitis (UC)

China
Bristol-Myers Squibb

Recruiting

An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice

Colitis, Ulcerative

United States
Janssen Research & Development, LLC

Recruiting

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis (DUET-UC)

Colitis, Ulcerative

United States, Denmark, Belgium, Austria, Greece, Korea, Republic of, United Kingdom, Israel, Poland, Japan, Hungary, Italy, Germany, Australia, Taiwan, New Zealand, Spain, Norway, China, Switzerland, India, Brazil, Croatia, Netherlands, Eston... and more
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis

Ulcerative Colitis | Efficacy, Self | Biologics | Mesalazine

China
Reistone Biopharma Company Limited

Recruiting

A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

China, United States, Georgia, Poland, Ukraine
Postgraduate Institute of Medical Education and...
All India Institute of Medical Sciences, New Delhi

Not yet recruiting

Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative Colitis (TOCASU)

Ulcerative Colitis
Bristol-Myers Squibb

Recruiting

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Colitis, Ulcerative

United States, Belgium, Germany, Japan, France, Russian Federation, Spain, Poland, Australia, Canada, Israel, United Kingdom
Amgen

Recruiting

Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Taiwan, Switzerland, Germany, Spain, Turkey, Greece, Japan, Denmark, Korea, Republic of, Austria, Italy, Netherlands, Poland, Romania, Belgium, Argentina, Bulgaria, Czechia, Finland, Hungary, Mexico, Latvia, France, Canada, Slovaki...
Yonsei University

Not yet recruiting

Efficacy and Safety of Vedolizumab in Biologic-naïve Korean Patients With Moderate to Severe Inflammatory Bowel Disease (VEDOKO-IIT)

Crohn's Disease and Ulcerative Colitis

Korea, Republic of
Glycominds, LLC
University of Chicago; Weill Medical College of Cornell University; University... and other collaborators

Recruiting

Prospective Multicenter Trial to Determine the Efficacy and Outcome of the UCRI Biomarker Panel and Algorithm to Detect Mucosal Healing in Moderate to Severe Ulcerative Colitis Patients.

Ulcerative Colitis

United States
OSE Immunotherapeutics

Recruiting

Study of OSE-127 vs Placebo in Patients With Moderate to Severe Active Ulcerative Colitis (CoTikiS)

Ulcerative Colitis

Belgium, Latvia, Bulgaria, Belarus, Croatia, Georgia, Hungary, Poland, Russian Federation, South Africa, Ukraine
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

A Cohort Study Comparing IFX to CS for Moderate to Severe UC (INSURE)

Moderate to Severe Ulcerative Colitis

China
Takeda

Recruiting

A Study of Kynteles Injection (Vedolizumab) in Adults With Moderate to Severe Ulcerative Colitis or Crohn's Disease or Chronic Pouchitis

Inflammatory Bowel Diseases | Crohn Disease | Colitis, Ulcerative

Korea, Republic of
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

Colitis, Ulcerative

United States, Israel, Canada, Italy, United Kingdom, Hungary, Japan, Australia, China, Greece, Belgium, Croatia, Korea, Republic of, Poland, Czechia
Takeda

Recruiting

A Study of Intravenous Vedolizumab Administered Every 4 Weeks in Japanese Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis

Japan
Janssen Research & Development, LLC

Recruiting

A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC) (UNIFI Jr)

Colitis, Ulcerative

Belgium, United States, United Kingdom, Israel, Japan, Germany, Hungary, Russian Federation, Poland
Pfizer

Recruiting

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Israel, Poland, Canada, Japan, Belgium, Spain, Hungary, Finland, France, United Kingdom, Australia, Germany, Italy, Sweden, Netherlands, Slovakia

Search clinical trials for: Severe Ulcerative colitis

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