Search clinical trials for: Severe or recalcitrant keratitis

Total 209893 results

Mallinckrodt

Completed

Impact of Acthar on Everyday Life of Participants With Severe Keratitis

Keratitis

United States
Dompé Farmaceutici S.p.A

Completed

Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study) (NGF0121)

Dry Eye

United States, Italy
Dompé Farmaceutici S.p.A

Completed

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

Dry Eye Syndrome

United States
Dompé Farmaceutici S.p.A

Completed

Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (NGF0221)

Dry Eye Syndrome

United States, Italy
Kowa Research Institute, Inc.

Completed

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Santen SAS

Completed

3-year Study in Dry Eye Disease Patients With Severe Keratitis Receiving Ikervis® (1mg/mL Ciclosporin)

Dry Eye Disease With Severe Keratitis

Czechia, France, Italy, Poland, Russian Federation, Spain, Turkey
Kuopio University Hospital
Business Finland; 4Pharma Ltd.; Finnsusp Ltd.

Completed

Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye

Dry Eye Syndrome

Finland
Cipher Pharmaceuticals Inc.

Completed

Efficacy and Safety of CIP-Isotretinoin in Patients With Severe Recalcitrant Nodular Acne

Severe Nodular Acne

United States, Canada
Wenzhou Medical University

Completed

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease

Moderate to Severe Dry Eye Syndrome

China
Allergan

Completed

Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome

Arthritis, Rheumatoid | Lupus Erythematosus, Systemic | Scleroderma, Systemic | Keratoconjunctivitis Sicca | Sjogren's Syndrome

United States
Washington University School of Medicine

Not yet recruiting

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Kaposi Sarcoma

United States
Alcon Research

Not yet recruiting

Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Regina Elena Cancer Institute

Recruiting

Analysis and Evaluation of Smoking Treatment With Cytisine

Moderate or Severe Tobacco Use Disorder

Italy
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Apollo Therapeutics Ltd

Recruiting

A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis

Dermatitis | Eczema | Atopic Dermatitis | Atopic | Eczema, Atopic | Dermatologic Disease | Eczema Atopic Dermatitis

United States, Canada
Hadassah Medical Organization
London North West Healthcare NHS Trust

Not yet recruiting

Severe COVID-19 Infection in Children Presenting to EDs in Israel and England (SPICE)

COVID-19 | Inflammatory Response
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
AbbVie

Not yet recruiting

An Observational Study to Assess Real-World Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in China (REACH-AD)

Atopic Dermatitis
China National Center for Cardiovascular Diseases

Not yet recruiting

Exploring the Clinical Efficacy of Remote Management Applications Through Comprehensive Physical Therapy for Patients With Moderate to Severe Sleep Apnea

Aerobic Exercise | M-health | OSAHS | Oropharyngeal Muscle Training | Comprehensive Physical Therapy
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Dompé Farmaceutici S.p.A

Recruiting

Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye (GEMINAE)

Dry Eye | Sjögren Syndrome

United States
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia

Mastalgia

China
Oneness Biotech Co., Ltd.

Not yet recruiting

Evaluate Efficacy, Pharmacokinetics, and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Sanofi
Regeneron Pharmaceuticals

Recruiting

Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France (OPALE)

Chronic Rhinosinusitis With Nasal Polyposis

France, Réunion
AbbVie

Not yet recruiting

A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis (Sleep Up)

Sleep Disturbance | Atopic Dermatitis
AbbVie

Recruiting

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (Switch-Up)

Atopic Dermatitis

United States
Diabetes Foundation, India
National Diabetes Obesity and Cholesterol Foundation

Recruiting

Comparison of Micro- and Macrovascular Disease(s) in People With T2D, Who Have Moderate to Severe Acanthosis Nigricans vs. Those Who do Not Have Acanthosis Nigricans

Type 2 Diabetes Mellitus With Complication

India
Assiut University

Not yet recruiting

Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.

Severe Pre-eclampsia
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK120 in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne

Moderate to Severe Acne Vulgaris

China
Regeneron Pharmaceuticals
Intellia Therapeutics

Not yet recruiting

A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B (BEYOND-9)

Hemophilia B
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
Saint Petersburg State University, Russia

Not yet recruiting

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Ischemic Heart Disease | Mitral Insufficiency | Aortic Stenosis, Severe | Mitral Stenosis | Aortic Insufficiency | Ascending Aortic Aneurysm | Mitral Stenosis With Insufficiency | Tricuspid Insufficiency

Russian Federation
Laboratoires Thea

Not yet recruiting

Comparison of the Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome.

Dry Eye Syndrome
MemorialCare Health System

Not yet recruiting

Preeclampsia Educational Program Study (PrEPS) (PrEPS)

Preeclampsia | Preeclampsia Postpartum | Preeclampsia Severe | Preeclampsia Mild
Uppsala University Hospital

Not yet recruiting

Mechanisms of Acute Kidney Injury in Severe Infections (PET-AKI)

Sepsis | AKI - Acute Kidney Injury | Positron Emission Tomography (PET)
Sensorion

Not yet recruiting

A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations (AUDIOGENE)

Otorhinolaryngologic Diseases | Ear Diseases | Hearing Disorders | Deafness | Hearing Loss, Sensorineural | Congenital Deafness | DFNB9 | OTOF Gene Mutation

France
Fudan University

Not yet recruiting

Newly Emerging Immunotherapy for Pancreatic Cancer Treatment (FD-IMPACT)

Pancreatic Cancer

China
Seventh Medical Center of PLA General Hospital
Guangdong Provincial People's Hospital; Henan Provincial People's Hospital; People... and other collaborators

Recruiting

Prone Position During ECMO in Pediatric Patients With Severe ARDS (PEPAD)

Extracorporeal Membrane Oxygenation | Pediatric Acute Respiratory Distress Syndrome

China
Regeneron Pharmaceuticals

Recruiting

Short-Term Linvoseltamab Treatment, on Top of Chronic Dupilumab Treatment, for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

Food Allergy

United States
Invirsa, Inc.

Recruiting

Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Poitiers University Hospital

Not yet recruiting

Anatomo-clinico-biological Profiles in Severe Nasal Polyps

NASAL POLYPS
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function

Alcoholic Hepatitis

India
Bristol-Myers Squibb

Recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Arrowhead Pharmaceuticals

Recruiting

Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia (SHASTA-3)

Severe Hypertriglyceridemia

United States
Corvus Pharmaceuticals, Inc.

Recruiting

Safety, Tolerability, and Preliminary Efficacy of Soquelitinib in Participants With Moderate to Severe AD

Atopic Dermatitis

United States
Mayo Clinic

Recruiting

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia

United States

Search clinical trials for: Severe or recalcitrant keratitis

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