Search clinical trials for: Single Dose

Total 25777 results

Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers

Asthma

China
The Affiliated Hospital of Qingdao University

Recruiting

Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial

Gastric Cancer

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/βC Genotype

Sickle Cell Disease
CSL Behring

Recruiting

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Complement Deficiencies

Australia
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
Pfizer

Recruiting

A Study for Two Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
Nanjing Ruijie Pharma Co., Ltd.

Recruiting

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Drug Safety

China
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Hyperlipemia

China
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Korea University Anam Hospital

Recruiting

A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke

Dyslipidemias | Stroke, Acute Ischemic

Korea, Republic of
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants

Healthy Participants

United States
The Affiliated Hospital of Qingdao University

Recruiting

XKDCT080 in GCC-positive Recurrent or Refractory Solid Tumors With Single Center, Single Arm, and Dose Escalation

Colon Cancer

China
HealthPartners Institute

Recruiting

Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose (INI-CSF)

Healthy

United States
Immunocore Ltd

Recruiting

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan, Denmark, United States, Australia, Romania, United Kingdom, Spain
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease (BUSTON-01)

Dry Eye Disease
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease (BUSTON-02)

Dry Eye Disease
Aer Therapeutics

Recruiting

Single and Multiple Ascending Dose Study of AER-01

COPD

Australia
Medical College of Wisconsin
University of Oklahoma

Recruiting

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage (TheoPHyLNNe)

Acute Kidney Injury | HIE

United States
Abdul El-Rabbany

Recruiting

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic Surgical Site Infection

Canada
Sirnaomics

Recruiting

Single Ascending Dose of FXI-GalNAc-siRNA in Healthy Subjects

FXI

United States, Canada
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
Federal University of Health Science of Porto Alegre

Not yet recruiting

Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS (L-AmB_phase3)

Fungal Infection | Immunosuppression | AIDS and Infections | Disseminated Histoplasma Capsulatum Infection

Brazil
David D'Andrea

Not yet recruiting

Single-Dose Intravesical Chemotherapy After Diagnostic URS (MINERVA)

Bladder Cancer | Upper Urinary Tract Urothelial Carcinoma

Austria
Peking University Third Hospital

Not yet recruiting

Single Ultra-high Dose Stereotactic Body Radiation Therapy for Early Lung Cancer (USBRT-1)

Stereotactic Body Radiotherapy | Early Lung Cancer

China
Brigham and Women's Hospital
Bill and Melinda Gates Foundation

Not yet recruiting

A Single-Dose, Three-Way, Three-Sequence, Crossover BA Study of Azithromycin Oleogel

Infectious Disease | Drug Effect | Clinical Infection
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Study of HS-10517 in Chinese Adult Participants

COVID-19

China
Ciusss de L'Est de l'Île de Montréal

Recruiting

Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block (DEXBIB)

Shoulder Pain | Anesthesia | Post Operative Pain

Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

Influenza

United States
Biocad

Recruiting

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL) (BLUEBELL)

Spinal Muscular Atrophy (SMA)

Belarus, Russian Federation
McMaster University
Center for Medicinal Cannabis Research

Recruiting

The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol (POT-GFR-PK)

Chronic Kidney Diseases | Cannabis | Dialysis

Canada
Zuyderland Medisch Centrum
AtriCure, Inc.

Recruiting

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (ICE)

Funnel Chest | Pectus Excavatum

Netherlands
Nirsum Labs
National Institute on Drug Abuse (NIDA)

Recruiting

Single Ascending Dose Study of NRS 033 in Healthy Volunteers

Healthy Volunteers

United States
First Affiliated Hospital, Sun Yat-Sen University
Baxter Healthcare Corporation

Recruiting

Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis

Peritoneal Dialysis

China
University of Reading
Wild Blueberry Association of North America (WBANA)

Recruiting

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Executive Function | Mood | Affect

United Kingdom
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Escalating Doses of SIM0348 as a Single Agent in Advanced Solid Tumors

Advanced Solid Tumors
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy (HYPOGRYPHE)

Melanoma | Renal Cell Carcinoma | NSCLC | SCLC | Breast Carcinoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Brain Metastases, Adult

United States
Mercy Health Ohio
Northeast Ohio Medical University

Recruiting

Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting

Urinary Tract Infections

United States
Centre for Chronic Disease Control, India
All India Institute of Medical Sciences, New Delhi; Imperial College London

Recruiting

Treatment Optimisation for Blood Pressure With Single-Pill Combinations in India (TOPSPIN)

Primary Hypertension

India
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Infectious Diseases Clinical...

Recruiting

Single Dose Antibiotic Treatment of Acute Watery Diarrhea, Rifaximin Versus Azithromycin, With Loperamide Adjunct (TrEAT_TD2)

Diarrhoea;Acute | Diarrhea Travelers

Djibouti, Honduras, Kenya
Beckley Psytech Limited

Recruiting

An Open-Label, Single Dose Study in Patients With Alcohol Use Disorder

Alcohol Use Disorder

United Kingdom
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
Juventas Cell Therapy Ltd.

Recruiting

A Study of CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)

B-cell Acute Lymphoblastic Leukemia

China
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants

Healthy Participants

United States
Beckley Psytech Limited

Recruiting

An Open-Label, Single Dose Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression

Treatment Resistant Depression

United Kingdom
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure

Chronic Heart Failure

United States, United Kingdom, Poland
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects

Healthy Volunteers

Australia

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