Search clinical trials for: Sodium Homeostasis

Total 10378 results

Klinikum Nürnberg

Recruiting

A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease. (DapaBalci-Leap)

Chronic Renal Failure | Mechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis

Germany, France
Maastricht University

Not yet recruiting

Role of BCAA in Glucose Homeostasis (NaPB2)

Type 2 Diabetes
Yale University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure

Heart Failure

United States
University Hospital Inselspital, Berne

Completed

Effects of Dapagliflozin on Hormonal Glucose Homeostasis in Type 1 Diabetes

Diabetes Mellitus, Type 1

Switzerland
Maastricht University
AstraZeneca

Completed

Effects of 2 Weeks Treatment With Dapagliflozin in Subjects With an Impaired Glucose Homeostasis on Nocturnal Substrate Oxidation (MaasFlex)

Prediabetic State | Substrate Oxidation

Netherlands
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Imperial College London

Completed

Propionate and Energy Homeostasis (PROEM)

Obesity

United Kingdom
Vanderbilt University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Aldosterone and Glucose Homeostasis

Diabetes Mellitus

United States
Garvan Institute of Medical Research

Completed

Alkaline Diet for Insulin Sensitivity (ADIS)

Type 2 Diabetes Mellitus | Dysglycemia

Australia
Rigshospitalet, Denmark
Bispebjerg Hospital

Completed

Effect of Methylprednisolone on Glucose Homeostasis in Patients Undergoing Total Hip- and Knee-arthroplasty

Osteoarthrosis

Denmark
Merck Sharp & Dohme LLC

Completed

Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)

Hypertension
Boehringer Ingelheim

Completed

A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects

Diabetes Mellitus, Type 2

Austria, Germany, Italy
ViiV Healthcare
GlaxoSmithKline

Completed

An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects

HIV-associated Lipodystrophy Syndrome

United States
Boston Children's Hospital
Massachusetts General Hospital

Completed

Effects of a Food Preservative on Glucose Homeostasis

Overweight

United States
Kolding Sygehus
Odense University Hospital; Regionshospitalet Holstebro, Holstebro, Denmark

Unknown

Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung Disease

Heart Failure | Aortic Stenosis | Healthy Volunteers | Ischemic Heart Disease | Pulmonary Hypertension

Denmark
The University of Texas Health Science Center at...
Baptist Health Foundation of San Antonio

Recruiting

Prevention of Progression of Prediabetes, Obesity and CV Risk (Pre-DM)

Cardiovascular Diseases | Weight, Body | Pre-Diabetes

United States
Institut National de la Santé Et de la Recherche...

Recruiting

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain (APEDOC)

Stroke

France
Craig Hospital
University of Colorado, Boulder

Recruiting

Role of Endothelial Function in SCI CVD Risk

Cardiovascular Diseases | Endothelial Dysfunction | Spinal Cord Injuries

United States
Rigshospitalet, Denmark

Not yet recruiting

Cocaine, Lidocaine/Xylometazoline and Saline for Nasal Analgesia

Analgesia
Institut de cancérologie Strasbourg Europe

Not yet recruiting

Role of Sodium-glucose Linked Transporter 2 (SGLT2) and Its Inhibitor Over CARdiotoxicity Induced by Anthracyclines and Breast Cancer Tumorigenesis SCARA-B (SCARA-B)

Breast Neoplasms

France
NYU Langone Health

Not yet recruiting

Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis

Acute Bronchiolitis

United States
University of Palermo

Not yet recruiting

SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF (DAPA-TONIC)

Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Diabetes Type 2 | Heart Failure Acute
Seoul National University Hospital

Not yet recruiting

Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss

Hearing Loss, Sensorineural | Hearing Loss, Sudden | Intratympanic Injection
Hospital de Clinicas de Porto Alegre
Vifor Pharma

Not yet recruiting

IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency (COMBINED-HF)

Heart Failure, Systolic | Iron Deficiencies

Brazil
University of Dundee
Juvenile Diabetes Research Foundation; Lexicon Pharmaceuticals

Not yet recruiting

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes (SOPHIST)

Heart Failure | Type 1 Diabetes
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
Beijing Anzhen Hospital

Not yet recruiting

Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation (DARE-AF)

Atrial Fibrillation

China
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy

Irreversible Pulpitis | Extremely Deep Caries | Partial Pulpotomy

India
Cairo University

Recruiting

Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Perioperative Pain Management

Egypt
Ann & Robert H Lurie Children's Hospital of Chicago
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease (SGLT2I-IN-KIDS)

Chronic Kidney Diseases | Pediatric Kidney Disease

United States
Ain Shams University

Not yet recruiting

The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.

Intraoperative Bleeding

Egypt
Galderma R&D

Recruiting

A Restylane Treatment Algorithm Approach for Participants With Appearance of Insufficient Bone Structure in the Lower Face Alone or in Combination With Facial Soft Tissue Deficiencies (ARTIST)

Chin Augmentation

Canada
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients

Dry Eye | Dry Eye Syndromes

Korea, Republic of
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Alberta; The University of Texas at Dallas; Parnassia Groep; EnLi...

Not yet recruiting

Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS (KISSeS)

Bipolar and Related Disorders | Psychosis | Schizophrenia and Related Disorders | Depressive Episode | Manic Episode
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Soren Schou Olesen
Aarhus University Hospital; University of Aarhus; Stanford University; Haukeland... and other collaborators

Not yet recruiting

Tocilizumab for Painful Chronic Pancreatitis (TOPAC)

Pancreatitis, Chronic

Denmark
Boehringer Ingelheim

Not yet recruiting

A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure
Afyonkarahisar Health Sciences University

Recruiting

Postoperative Pain Control Following Hysteroscopy

Postoperative Pain | Analgesia | Postoperative Nausea

Turkey
Ain Shams University

Recruiting

Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients

Chronic Kidney Diseases

Egypt
E-DA Hospital

Recruiting

2% Lidocaine Gel in Reducing Postoperative Pain Following Haemorrhoidectomy

Pain, Postoperative | Surgery

Taiwan
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
Gødstrup Hospital

Not yet recruiting

Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity ((KETO-HT))

Essential Hypertension | Ketosis
Mansoura University

Recruiting

Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years

Nephrotic Syndrome in Children

Egypt
HighTide Biopharma Pty Ltd
Shenzhen HighTide Biopharmaceutical Ltd.

Recruiting

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

T2DM (Type 2 Diabetes Mellitus)

China
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
Sidney Kimmel Comprehensive Cancer Center at Johns...
Agenus Inc.; Private Philanthropic Funds

Not yet recruiting

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Colorectal Cancer | Pancreatic Cancer

United States
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany

Search clinical trials for: Sodium Homeostasis

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