Search clinical trials for: Sparing antibiotic strategy

Total 11178 results

University Hospital, Lille
Ministry of Health, France

Not yet recruiting

Antibiotic Strategy and Asymptomatic Bacteriuria in the Context of Intra-vesical Botulinum Toxin A Injections. (ANTIBIOBONTA)

Urinary Tract Disease

France
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth (AUTOP2)

Bacterial Vaginosis | Premature Delivery | Vaginal Dysbiosis
Children's Hospital of Philadelphia
Johns Hopkins University; University of Pennsylvania; Centers for Disease Control... and other collaborators

Recruiting

Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis (REVAMP)

Sepsis | Septic Shock | Sepsis, Severe | Sepsis Bacteremia | Sepsis Mrsa | Antimicrobial - Induced Nephropathy | Septic Syndrome

United States
UroGen Pharma Ltd.

Recruiting

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto (uTRACT)

Carcinoma, Transitional Cell | Urothelial Carcinoma | Urothelial Cancer of Renal Pelvis | Urothelial Carcinoma Ureter | Urothelial Carcinoma Recurrent | Urothelial Carcinoma of the Renal Pelvis and Ureter | Urothelial Carcinoma Ureter Recurrent | Transitional Cell Carcinoma of Renal Pelvis

United States
University Hospital, Lille

Recruiting

Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation (RESPIRE)

Pneumonia, Ventilator-Associated | Immunodeficiency | Pneumonia, Hospital-Acquired

France
Ulrikka Nygaard
University of Copenhagen; Innovation Fund Denmark

Recruiting

Individualized Duration of Antibiotic Treatment in Early Onset Infection in Newborns. (DurATi-n)

Antibiotic Side Effect | Early-Onset Neonatal Sepsis

Denmark
Nantes University Hospital

Recruiting

Delayed Antibiotic Therapy in Non-severe Ventilator Acquired Pneumonia (VAP) (DELAVAP)

Ventilator Associated Pneumonia | Critical Care | Antibiotic Therapy

France
University Hospital, Strasbourg, France

Recruiting

Efficiency of the Imaging Strategy for the Management of Pneumonia (EFFI-PNEUMO)

Pneumonia

France
Peking Union Medical College Hospital

Recruiting

Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes

Postoperative Infection | Antibiotics | Lactate

China
Foundation for Innovative New Diagnostics, Switzerland
Ministry of Health, Senegal; Institut Pasteur de Dakar

Recruiting

Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal

Pneumonia | Diarrhea | Malaria | Dengue | Acute Febrile Illness | Influenza -Like Illness

Senegal
Major Extremity Trauma Research Consortium
United States Department of Defense

Recruiting

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Post Operative Surgical Site Infection

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses. (POOMA)

Osteomyelitis

France
Shanghai Children's Medical Center
Shanghai Children's Hospital

Recruiting

A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy

Hepatoblastoma

China
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Antibiotic Therapy

Singapore
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Antibiotic Therapy In Respiratory Tract Infections (AIR)

Community-Acquired Pneumonia

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia. (SHARP)

Hospital-acquired Pneumonia

France
Academisch Medisch Centrum - Universiteit van Amsterdam...
Bristol-Myers Squibb

Recruiting

A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study (CRIMI)

Urinary Bladder Cancer | Invasive Bladder Cancer

Netherlands
University Hospital, Lille

Recruiting

Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation (APAPI)

Aspiration Pneumonia

France
University Hospital, Lille
Curetis GmbH

Recruiting

Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia (VAPERO)

Pneumonia, Bacterial | Pneumonia, Ventilator-Associated

France
German Breast Group
Pfizer; AMS Advanced Medical Services GmbH

Recruiting

A Randomized, Open-label, Multi-center Phase IV Study Evaluating Palbociclib Plus Endocrine Treatment Versus a Chemotherapy-based Treatment Strategy in Patients With Hormone Receptor Positive / HER2 Negative Breast Cancer in a Real World Setting (GBG 93 - PADMA Study). (PADMA)

Metastatic Breast Cancer

Germany
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Sun Yat-sen University

Recruiting

Prospective Study of Fertility-sparing Treatment Strategy in Patients With Early Cervical Cancer(SYSUGO-005/CSEM009) (SYSUGO-005)

Cervical Cancer

China
M.D. Anderson Cancer Center
Cancer Prevention Research Institute of Texas

Enrolling by invitation

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

Delirium | Epileptics | Neuroleptics

United States
Kaohsiung Veterans General Hospital.

Completed

Dexmedetomidine in Thoracoscopic Surgery: Opioid-Sparing Strategy

Postoperative Pain | Opioid Use

Taiwan
Centre Cardiologique du Nord
Universita degli Studi di Genova; Campus Bio-Medico University; Henri Mondor... and other collaborators

Enrolling by invitation

Optimal Strategy for Repair of Type A Acute Aortic Dissection (TARAD)

Aortic Dissection

France
Ramon Gorter
Amsterdam UMC, location VUmc; ZonMw: The Netherlands Organisation for Health...

Active, not recruiting

Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children (APAC)

Appendicitis

Netherlands
Assistance Publique - Hôpitaux de Paris

Completed

Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock (SSS)

Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit

France
Centre Leon Berard

Completed

A Multicenter Study to Evaluate a Risk-adapted Strategy for Treatment of Extra Cranial Non Seminomateous Malignant Germ Cell Tumour in Children and Adolescent

Extra Cranial Non Seminomateous Malignant Germ Cell Tumour

France
McMaster University
Canadian Institutes of Health Research (CIHR); Hamilton Health Sciences Corporation and other collaborators

Completed

SQUEEZE Trial: A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care (SQUEEZE)

Septic Shock

Canada
Prisma Health-Upstate

Completed

Opioid Sparing Pain Management Strategy

Cardiac Surgical Procedures

United States
Assistance Publique - Hôpitaux de Paris

Completed

Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children (OPTIBAYE)

Methicillin-resistant Staphylococcal Infections

France
Tanta University

Unknown

Clinical Evaluation of New Treatment Strategy of Mucous Membrane Pemphigoid Using Large Dose of Prednisolone Plus Intra-lesional of Triamcinolone Acetonide Followed by Combination of Mycophenolate Mofetil, Dapsone and Low Dose Prednisolone

Benign Mucous Membrane Pemphigoid

Egypt
UroGen Pharma Ltd.

Completed

The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study (Olympus)

Carcinoma, Transitional Cell | Transitional Cell Carcinoma of Renal Pelvis

United States, Israel
University of Minnesota
Wyeth is now a wholly owned subsidiary of Pfizer; Roche Pharma AG; Genzyme, a...

Completed

Calcineurin Inhibitor Sparing After Kidney Transplantation (CNI-Sparing)

CNI Side Effects

United States
Columbia University

Terminated

Trimodal Lung-Sparing Treatment of Pleural Mesothelioma

Pleural Mesothelioma

United States
UroGen Pharma Ltd.

Withdrawn

Efficacy and Safety of UGN-101 in Recurrent Patients (Retreatment)

Carcinoma | Transitional Cell Carcinoma | Transitional Cell Cancer of the Renal Pelvis and Ureter

Israel, United States
Bayer

Completed

Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and Midazolam

Biological Availability

Germany
Baylor College of Medicine

Terminated

Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation

Renal Insufficiency | Renal Failure | End-stage Liver Disease

United States
Fundacion para la Investigacion Biomedica del Hospital...

Terminated

Approach for Optimizing Meropenem Therapy in Intubated and Mechanically-Ventilated, Adult Patients With Severe Gram-Negative Lower Respiratory Tract Infection (MON4STRAT)

Lower Respiratory Tract Infection

Belgium, Spain, France
Sung-Han Kim

Unknown

Strategy to Prevent Transmission of Multidrug-resistant Gram-negative Organisms in ICU

Antibiotic Resistant Infection

Korea, Republic of
Novartis Pharmaceuticals

Completed

REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy (REFLECT)

Liver Transplantation

Italy
University Hospital, Bordeaux
Novartis

Completed

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A (EVERCMV)

Transplantation Infection | Cytomegalovirus Infection

France
Novartis Pharmaceuticals

Completed

A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients (MANDELA)

Heart Transplantation

Germany
Shandong University
Shandong Provincial Hospital; Liaocheng People's Hospital; Binzhou People's Hospital and other collaborators

Unknown

Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment

Helicobacter Pylori Infection | Antimicrobial Susceptibility Testing

China
Merck Sharp & Dohme LLC

Completed

A De-Escalating Strategy for Antibiotic Treatment of Pneumonia in The Medical Intensive Care Unit (0787B-092)

Pneumonia | Infection
Hospital General de Niños Pedro de Elizalde

Completed

Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Community Acquired Pneumonia

Pneumonia

Argentina
Yonsei University

Withdrawn

A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)

Congestive Heart Failure
McMaster Children's Hospital
McMaster University; Hamilton Health Sciences Corporation; Canadian Critical...

Completed

Pilot Study for the SQUEEZE Trial (SQUEEZE)

Septic Shock

Canada
Samsung Medical Center

Unknown

Optimal Treatment Strategy Based on for Pediatric AML

Pediatric Acute Myeloid Leukemia

Korea, Republic of

Search clinical trials for: Sparing antibiotic strategy

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