Search clinical trials for: Systemic Impairment

Total 11630 results

Assiut University

Not yet recruiting

Renal Assessment for Early Detection of Renal Impairment in Systemic Sclerosis and Systemic Lupus Erythematosus Patients

Systemic Sclerosis and Systemic Lupus Erythematous
Lithuanian Sports University
KU Leuven; Lithuanian University of Health Sciences; Wingate Institute; Maastricht... and other collaborators

Recruiting

The Impact of 6-months of Resistance Training on Brain and Muscle Health in Older Adults With MCI

Mild Cognitive Impairment | Older Adults at High Risk for MCI

Lithuania
UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Royal... and other collaborators

Not yet recruiting

Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)

Systemic Sclerosis
Fundacion Clinic per a la Recerca Biomédica

Not yet recruiting

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis (OraPAT-IEGAMES)

Endocarditis Infective

Spain
Tsinghua University
Peking Union Medical College Hospital

Recruiting

Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging Study

Systemic Sclerosis | Multisystem Disorder

China
California Institute of Integral Studies

Not yet recruiting

The Grounded Brain: How Sleeping Grounded Affects Memory and Perceptions

Mild Cognitive Impairment | Chronic Inflammation
Karolinska Institutet
Université Catholique de Louvain

Recruiting

Per-protocol Repeat Kidney Biopsy in Incident Cases of Lupus Nephritis (REBIOLUP)

Lupus Nephritis

Sweden
Vanderbilt University Medical Center
The University of Texas Health Science Center, Houston; The Cleveland Clinic; Evergreen Therapeutics, Inc...

Recruiting

Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus (ClearMEMory)

Lupus Erythematosus, Systemic

United States
Karin Hoth
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

COPD-Related Physiology and the Brain

Cognitive Impairment | Pulmonary Disease, Chronic Obstructive (COPD)

United States
Saint Petersburg State University, Russia

Withdrawn

Dabrafenib and Trametinib Combination as a Neoadjuvant Strategy in BRAF-positive Anaplastic Thyroid Cancer (ANAPLAST-NEO)

Thyroid Gland Anaplastic Carcinoma

Russian Federation
Jian-jun Yang

Completed

Functional Magnetic Resonance Imaging (fMRI) of Brain in ICU Survivors With Cognitive Impairment

Inflammation | Septic Shock | Cognitive Impairment | Functional Magnetic Resonance Imaging

China
Deciphera Pharmaceuticals LLC

Completed

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Gastrointestinal Stromal Tumors | Advanced Cancers | Advanced Systemic Mastocytosis

United States, Canada, Germany, Italy, Netherlands, United Kingdom
Vanderbilt University Medical Center
National Institutes of Health (NIH); National Institute of General Medical...

Active, not recruiting

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study (INSIGHT-ICU)

Delirium | Critical Illness | Cognitive Impairment | Trauma | Traumatic Brain Injury | ICU | Polytrauma | Alzheimer; Early Onset

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
University Hospital, Grenoble
Centre Hospitalier Universitaire de Saint Etienne; University Hospital, Clermont-Ferrand and other collaborators

Terminated

Cardiovascular Impairments and Obstructive Sleep Apnea Syndrome (INFRASAS)

Obstructive Sleep Apnea Syndrome | Subclinical Cardiovascular Impairments

France
Vanderbilt University Medical Center

Completed

The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure (MENDS2)

Sepsis | Delirium | Impaired Cognition

United States
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

COVID-19 Search in Conjunctival Cells (COVID-T)

COVID 19 | Pulmonary Disease

Italy
Assiut University

Unknown

Serum Ceramides Level in Systemic Lupus Erythematosus (SLE) Patients as a Novel Marker for Renal Impairment

Systemic Lupus
Acrotech Biopharma Inc.
Axis Clinicals Limited

Terminated

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Relapsed/Refractory Solid Tumors/Hematological Malignancies

United States
Karolinska University Hospital

Completed

HMGB1 in ICU-survivors

Sepsis | Cognitive Impairment

Sweden
University of Nottingham

Unknown

Systemic Hormones and Muscle Protein Synthesis

Sarcopenia | Muscle Atrophy | Muscle Hypotrophy

United Kingdom
Cubist Pharmaceuticals LLC

Terminated

Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment (RENSE)

Renal Impairment | Complicated Skin and Skin Structure Infections | S. Aureus Bacteremia

United States
Intermountain Health Care, Inc.
University of Utah

Completed

Systems Biology Approach to Cognitive Impairment After SepsiS (CASS)

Sepsis | Cognitive Impairment

United States
Nathan Kline Institute for Psychiatric Research

Completed

Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia

Diabetes | Schizophrenia | Cognitive Impairment | Insulin Resistance

United States
GlaxoSmithKline

Completed

A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers

Sepsis

Slovakia
Novartis Pharmaceuticals

Withdrawn

24 Week Study to Compare Systemic VEGF-levels of Ranibizumab and Aflibercept in DME. (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Type 2 Diabetes Patients With Moderate Renal Impairment

Diabetes Mellitus Type 2

Australia, Hong Kong, Colombia, Russian Federation, Germany, Hungary, Italy, Mexico, Peru, Romania, Slovakia, Brazil, El Salvador
Novartis Pharmaceuticals

Withdrawn

Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema

Germany
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Duke University

Terminated

Ammonia Levels and Cognitive Impairment

Cognitive Impairment | Dementia | Cognitive Decline | Developmental Delay

United States
Bayer

Completed

Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist

Fibrosis | Renal Insufficiency | Kidney Failure

United States
Austin Health

Completed

Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study (BLISS)

Systemic Inflammatory Response Syndrome | Renal Impairment | Oliguria

Australia
University Hospital, Rouen

Completed

Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up

Systemic Sclerosis

France
Kettering Health Network

Withdrawn

Magnetic Resonance Imaging (MRI) of Tumor Response and Cognitive Impairment in Breast Cancer Patients Undergoing Chemotherapy

Breast Cancer

United States
Rijnstate Hospital
GlaxoSmithKline

Completed

Pulmonary Function, Chronic Obstructive Pulmonary Disease (COPD) Prevalence, and Systemic Inflammation in Chronic Heart Failure With or Without COPD

Heart Failure | Inflammation | Pulmonary Disease, Chronic Obstructive

Netherlands
Bayer

Not yet recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment
University Hospital, Ghent

Recruiting

Amyloid PET in Patients With Mild Cognitive Impairment and Early Dementia

MCI

Belgium
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Pernille Louise Kjeldsen
University of Aarhus; Innovation Fund Denmark; Brain+ ApS; Eurostars EUREKA

Not yet recruiting

The Feasibility and Effect of Digital Cognitive Training in Mild Cognitive Impairment

Mild Cognitive Impairment

Denmark
University Ghent
University Hospital, Ghent

Recruiting

Validation Of The Flemish Montreal Cognitive Assessment (MoCA) For Persons With Hearing Impairment (MoCA-HI)

Dementia | Hearing Loss

Belgium
Northwestern University

Not yet recruiting

Fisetin to Reduce Senescence and Mobility Impairment in PAD (FIRST)

Peripheral Arterial Disease | Peripheral Vascular Diseases | Aging | Walking, Difficulty
Wuhan Union Hospital, China
ITabMed Co., Ltd.

Not yet recruiting

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Amsterdam UMC

Not yet recruiting

Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease (NESCIO-PD)

Parkinson Disease | Mild Cognitive Impairment
NeuroVision Imaging

Recruiting

Effect of LEQEMBI on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment

United States
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Azienda Usl di Bologna
Montecatone Rehabilitation Institute S.p.A.

Not yet recruiting

intErnet-based iNterventions FOR Cardiac arrEst suRvivors (ENFORCER)

Quality of Life | Cognitive Impairment | Sexual Dysfunction | Cardiac Arrest | Depression, Anxiety | Social Functioning

Italy
Eyestem Research Pvt. Ltd.

Not yet recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease
RenJi Hospital

Not yet recruiting

Efficacy and Safety of Telitacicept for Prevention of Flares in SLE Patients

Systemic Lupus Erythematosus

Search clinical trials for: Systemic Impairment

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