Search clinical trials for: TDM-1

Total 48709 results

Technoderma Medicines Inc.
Therapeutics, Inc.

Recruiting

Study of TDM-180935 in Atopic Dermatitis Patients

Atopic Dermatitis

United States
Catharina Ziekenhuis Eindhoven

Recruiting

Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT (THOMAS FU FLOT)

TDM of 5-FU | Pharmacokinetic Observational Study

Netherlands
Institut Cancerologie de l'Ouest

Active, not recruiting

Bringing of PET-TDM FDG in the Determination of the Characteristics of Primary Mammary Tumors TrIple Negatives (FICTION)

Breast Cancer

France
Genentech, Inc.

Completed

Trastuzumab and Trastuzumab-MCC-DM1 Administered Intravenously and GDC-0941 Administered Orally to Patients With HER2-Positive Metastatic Breast Cancer Who Have Progressed on Previous Trastuzumab-Based Therapy

Metastatic Breast Cancer

United States
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

Study of TDM-105795 Following Topical Administration in Male Subjects With Androgenetic Alopecia

Alopecia, Androgenetic

United States
Merrimack Pharmaceuticals

Terminated

MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients (HERMIONE)

Breast Cancer | HER2 Positive Breast Cancer

Spain, United States, Italy, France, Canada, Belgium, Austria, Germany, Czech Republic
Hoffmann-La Roche

Completed

A Study of the Efficacy and Safety of Trastuzumab Emtansine (Trastuzumab-MCC-DM1) vs. Trastuzumab (Herceptin®) and Docetaxel (Taxotere®) in Patients With Metastatic HER2-positive Breast Cancer Who Have Not Received Prior Chemotherapy for Metastatic Disease

Breast Cancer
Assistance Publique - Hôpitaux de Paris

Completed

Impact of PET Scan on the Curative Strategy of Colo-rectal Cancers : A Randomized Study (ITEP)

Colorectal Cancer

France
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

A Phase 1 Study of TDM-180935 Following Topical Administration in Healthy Male Subjects

Healthy

United States
University Hospital, Montpellier

Terminated

Effect of Ageing on Airway Remodeling

Aging

France
Jan-Willem C Alffenaar
University of Virginia; Kibong'oto Infectious Diseases Hospital

Completed

Saliva and Dried Blood Spot Therapeutic Drug Monitoring for MDR-TB in Tanzania

MDR-TB

Tanzania
University of Lausanne Hospitals

Completed

Ga-68-NODAGA-MJ9 Compared to F-18-FCH PET/CT for Prostate Cancer Patients

Prostate Cancer

Switzerland
University Hospital, Ghent
Belgium Health Care Knowledge Centre

Not yet recruiting

Proactive TDM Versus Standard Use of Biologics in Psoriasis (HELIOS)

Psoriasis Vulgaris

Belgium
Insel Gruppe AG, University Hospital Bern

Recruiting

Assessing Ultra-low Dose PET/CT and CT-less PET Using a Long Axial Field-of-view PET/CT System (ULD-PET)

PET/CT

Switzerland
Philips Healthcare (Suzhou) Co., Ltd.
The Second Hospital of Nanjing Medical University

Not yet recruiting

Incisive CT Clinica Trial Protocol

CT Images
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Comparison of Tumor Glucose Metabolism Before and After Artificial Nutrition (PETANC)

Head and Neck Cancer | Oesophageal Cancer

France
Duke University

Suspended

Assessing Muscle Metabolic Phenotype by MSK Ultrasound

Ultrasound | CT | MuscleSound

United States
Seoul National University Hospital

Completed

Comparison of NEOVIST 370 INJ.(Iopromide 768.86mg) With Ultravist 370 INJ.(Iopromide 768.86mg) in Abdominal CT

Abdominal CT
Johns Hopkins University
Pfizer

Completed

A Trial Comparing Efficacy and Safety of Voriconazole Administered With Therapeutic Drug Monitoring vs. Standard Dosing (VoriTDM)

Fungal Infection

United States
Assistance Publique Hopitaux De Marseille

Not yet recruiting

PhaRmacOgenetics and Therapeutic Drug Monitoring In SchizophrEnia (PROMISE)

Patients With Schizophrenia
GE Healthcare
University of Chicago; University of Washington

Recruiting

Clinical Data Collection and Evaluation of ECG-Less Cardiac CT

Cardiac CT

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Terminated

Evaluation of Attenuation Correction Accuracy in Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI)

PET/CT

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Impact of Reconstruction Method (ASIR, FBP) Used in CT on Bone SPECT/CT Image Quality (AsirTest)

SPECT-CT

France
University of Sao Paulo General Hospital
InCor Heart Institute; 3-D Matrix Medical Technology

Unknown

Strategy for Aortic Surgery Hemostasis (SASH)

Ascending Aorta Abnormality | Ascending Aortic Dissection | Ascending Aorta Aneurysm

Brazil
Genentech, Inc.

No longer available

A Study of Trastuzumab-MCC-DM1 in Patients With HER2- Positive Locally Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Washington University School of Medicine
Siemens Corporation, Corporate Technology

Recruiting

Gated and Non-Gated Dynamic PET/CT Imaging

Dynamic PET/CT Imaging

United States
University of Cincinnati
National Cancer Institute (NCI); Ohio Third Frontier

Active, not recruiting

Validating Low FDG Dose PET/CT Compared to Current Standard of Care Dose PET/CT

PET/CT Imaging

United States
Far Eastern Memorial Hospital

Completed

Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary Angiography (DSCT)

Coronary Angiography | CT

Taiwan
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Combination PET With 18F-fluorodeoxyglucose (18F-FDG) and 18 F-choline in Patient With HCC (PET-HCC01)

Hepatocellular Carcinoma

France
Sir Mortimer B. Davis - Jewish General Hospital

Enrolling by invitation

Fluorocholine PET/CT Basket Trial

Fluorocholine PET/CT

Canada
Assiut University

Unknown

Negative Oral Contrast Agents Utilization in PET/CT Studies

PET/CT | Oral Contrast

Egypt
Zhongnan Hospital

Recruiting

Integrin αvβ6-targeted PET in Malignant Tumors

Malignant Neoplasm | PET/CT | Integrin αvβ6

China
Yonsei University

Completed

The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Prospective Study

Children Requiring Sedation for MRI/CT

Korea, Republic of
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Comparison of Cone Beam Irradiation Versus Multi-detector Scanner for Ear Imaging (ICSI)

Irradiation; Adverse Effect
Royal Marsden NHS Foundation Trust
City, University of London

Unknown

Radiation Exposure Awareness From Patients Undergoing Nuclear Medicine Diagnostic Scans (REA)

FDG PET/CT | Skeletal Scintigraphy

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Using Drug Levels in the Blood to Guide Therapy in HIV Infected Patients Taking a Protease Inhibitor

HIV Infections

United States, Puerto Rico
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

A Study of TDM-105795 in Male Subjects With Androgenetic Alopecia (AGA)

Alopecia, Androgenetic

United States
Radboud University Medical Center
Turku University Hospital; Charite University, Berlin, Germany; University Medical... and other collaborators

Unknown

GLP-1 Receptor Expression in CHI (GLP-1-CHI)

Congenital Hyperinsulinism

Netherlands
Ludwig-Maximilians - University of Munich

Completed

Therapeutic Drug Monitoring of Antiinfectives for Patients With Severe Illness = TAPSI (TAPSI)

Infection, Bacterial

Germany
Yonsei University

Unknown

The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Retrospective Study

Children Requiring Sedation for MRI/CT

Korea, Republic of
Hospital Italiano de Buenos Aires

Completed

Individualized Antiretroviral Therapy (IAT)

HIV | Pharmacogenetics | Drug Monitoring

Argentina
Reema A. Patel

Recruiting

Imatinib TDM in GIST

Gastrointestinal Stromal Tumors

United States
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Singapore General Hospital

Recruiting

Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial Infections (TDM-RCT)

Sepsis | Bacterial Infections | Therapeutic Drug Monitoring | Hemodynamic Instability | Antimicrobial Resistance

Singapore
Inje University
Ministry of Science and ICT

Recruiting

Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB)

Latent Tuberculosis | Tuberculosis | Nontuberculous Mycobacterium Infection

Korea, Republic of, Indonesia
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

A Phase 1 Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA) (AGA)

Alopecia, Androgenetic

United States
Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
Anders Fink-Jensen, MD, DMSci
Rigshospitalet, Denmark; University of Copenhagen

Completed

The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring.

Schizophrenia

Denmark
Aarhus University Hospital

Completed

TDM of Asparaginase in ALL2008

Acute Lymphoblastic Leukemia

Denmark

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