Search clinical trials for: TNF-α inhibitor

Total 67909 results

Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
Dan Liang

Recruiting

Reduction or Discontinuation of TNF-α Inhibitor in Non-infectious Uveitis Patients

Uveitis | Adalimumab

China
Assistance Publique - Hôpitaux de Paris
Societe Francaise de Rhumatologie

Recruiting

French National Registry: ART REGISTRY (Observational Study) (ART)

RheumatoId Arthritis

France
Janssen Biotech, Inc.

Active, not recruiting

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease (DEVELOP)

Inflammatory Bowel Diseases | Crohn's Disease | Ulcerative Colitis | Indeterminate Colitis

United States, Canada
Ferring Pharmaceuticals

Completed

Extension Study of Semapimod 60 mg IV x 3 Days (CD06)

Crohn's Disease

United States, Netherlands, Israel, Germany
Amgen

Completed

Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United States, Belgium, Austria, Singapore, Australia, Netherlands, France, Japan, Taiwan, Canada
Vastra Gotaland Region

Active, not recruiting

Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients (NeuMRA)

Depression | Brain Diseases | Pain | Fatigue | Rheumatoid Arthritis | Cognitive Decline | Hand Rheumatism

Sweden
Korea Otsuka Pharmaceutical Co., Ltd.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Pharmacokinetics of Probucol and Cilostazol

Healthy

Korea, Republic of
Damanhour University

Completed

Alpha-Lipoic Acid in Breast Cancer Patients

Breast Cancer | Chemotherapeutic Toxicity

Egypt
Columbia University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

RHYTHM (Formerly Escape II Myocardium) (RHYTHM)

Rheumatoid Arthritis

United States
University of Erlangen-Nürnberg Medical School

Completed

Comparing the Efficacy of Periarticular Bone Structure in Patients Treated With Either Tocilizumab or Tumor Necrosis Factor Blockers (Re-Bone)

Rheumatoid Arthritis

Germany
Nanjing First Hospital, Nanjing Medical University

Completed

Epidural Intervention of Spinal Nerves With Tumor Necrosis Factor-Alpha Inhibitor

Spinal Stenosis
Life Extension Foundation Inc.

Completed

Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Lars Rombo

Completed

Hepatitis A Vaccine in Patients With Immunomodulating Drugs

Response to Hepatitis A Vaccine

Finland, Sweden
Sormland County Council, Sweden

Unknown

Three Doses of Hepatitis A Vaccine in Patients With Immunomodulating Drugs

Vaccine Response Impaired

Sweden
National Institute of Nursing Research (NINR)
Fred Hutchinson Cancer Center

Terminated

Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis

Stomatitis | Graft-versus-Host Disease

United States
Assistance Publique - Hôpitaux de Paris

Completed

Lumbar Spinal Fibrosis and TNF Alpha Inhibition

Post Operative Sciatica by Lumbar Spinal Fibrosis

France
Tehran University of Medical Sciences

Unknown

The Combined Effects of omega3 Fatty Acids and Curcumin Supplementation on Inflammatory and Endothelial Factors in Migraine Patients

Migraine
Glostrup University Hospital, Copenhagen

Terminated

Discontinuation of TNF-alpha Inhibitors in Patients With Spondyloarthritis (SPARTA)

SPONDYLOARTHRITIS

Denmark
Ludwig Institute for Cancer Research
Johns Hopkins University

Withdrawn

Single Dose of Intravenous rhTNF-α and Liposomal Doxorubicin in Patients With Advanced Solid Tumors or Lymphomas

Solid Tumors | Lymphomas

Germany
Medical University of Vienna

Completed

On the Impact of Therapeutic Tumor Necrosis Factor-alpha Inhibition on Anogenital Human Papillomavirus Infection

Inflammatory Bowel Diseases | Psoriasis
M.D. Anderson Cancer Center
National Institutes of Health (NIH)

Withdrawn

Efficacy of NF-kB Inhibition for Reducing Symptoms During Maintenance Therapy in Multiple Myeloma Patients

Multiple Myeloma
Ferring Pharmaceuticals

Completed

Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease (CD05)

Crohn's Disease

United States, Netherlands, Israel, Belgium, Germany
Indonesia University

Unknown

Effect of Simvastatin on Pneumonia Prognosis in Elderly Patients

Community-Acquired Pneumonia

Indonesia
Altschuler, Eric, M.D.
GlaxoSmithKline

Completed

A Trial of Wellbutrin for Crohn's Disease

Crohn Disease

United States
Zhejiang Cancer Hospital

Not yet recruiting

Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer

Gastric Cancer

China
Beijing Tongren Hospital
The First Affiliated Hospital with Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Reversal of Neuromuscular Blockade

China
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
First Affiliated Hospital of Zhejiang University
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML

Myeloid Malignancy | Relapsed/Refractory Acute Myeloid Leukaemia

China
Hospital de Clinicas de Porto Alegre
Vifor Pharma

Not yet recruiting

IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency (COMBINED-HF)

Heart Failure, Systolic | Iron Deficiencies

Brazil
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
Roswell Park Cancer Institute

Not yet recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Unresectable Triple-Negative Breast Carcinoma

United States
TC Erciyes University

Not yet recruiting

The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction

Middle Ear Disease
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

Sequential Multiple Assignment Randomized Trial for Bipolar Depression (SMART-BD)

Depression | Bipolar I Disorder

United States, Canada
University of Dundee
Juvenile Diabetes Research Foundation; Lexicon Pharmaceuticals

Not yet recruiting

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes (SOPHIST)

Heart Failure | Type 1 Diabetes
Chengdu Baiyu Pharmaceutical Co., Ltd.

Recruiting

A Phase l Study of By101921, an Oral PARP7 Inhibitor, in Patients With Advanced Solid Tumors

Solid Tumor, Adult

China
Daping Hospital and the Research Institute of Surgery...

Not yet recruiting

Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
Sun Yat-sen University

Not yet recruiting

Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer

Colorectal Cancer

China
JW Pharmaceutical

Not yet recruiting

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Healthy

Korea, Republic of
Johns Hopkins University

Recruiting

Opioid Use After Laparoscopic Salpingectomy

Opioid Use | Post-operative Pain | Sterility, Female

United States
Beijing Anzhen Hospital

Not yet recruiting

Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation (DARE-AF)

Atrial Fibrillation

China
Post Graduate Institute of Medical Education and...
Indian Council of Medical Research

Not yet recruiting

Carvedilol + Simvastatin vs. Carvedilol Alone for Chronic Liver Disease and Cirrhotic Cardiomyopathy and Its Impact on Hepatic Decompensation and Survival; a Double-blind Randomized Controlled Trial (CIRROSTAT)

Decompensated Cirrhosis | Acute Kidney Injury | Cirrhosis, Liver | Left Ventricular Diastolic Dysfunction | Cirrhotic Cardiomyopathy
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Ovarian Cancer

United States, Germany
Shenzhen Institute of Advanced Technology, Chinese...

Recruiting

Variation in the Impact of Coffee on the Metabolic Rate

Healthy

China
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
University of Saskatchewan

Recruiting

Three Dimensional Ultrasonographic Detection of Human Ovulation

Ovulation Disorder

Canada
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
Ba Yi
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
China National Center for Cardiovascular Diseases

Recruiting

Potts-shunt for the Treatment of Pediatric Patients With Severe Pulmonary Hypertension

Pulmonary Artery Hypertension

China

Search clinical trials for: TNF-α inhibitor

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