Search clinical trials for: Tenofovir alafenamide (TAF)

Total 1237 results

Stanford University
Gilead Sciences

Completed

Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic

United States, Taiwan, Japan, Korea, Republic of
National Taiwan University Hospital
Chiayi Christian Hospital; E-DA Hospital; Taipei City Hospital; Taipei Tzu Chi... and other collaborators

Recruiting

Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue (CHANGE)

Chronic Hepatitis b | Hepatitis B Reactivation

Taiwan
Cwm Taf University Health Board (NHS)

Suspended

Exploring Breathing Patterns (EPISODE)

COPD

United Kingdom
Gilead Sciences

Recruiting

Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination in Adolescents and Children With Human Immunodeficiency Virus-1

HIV-1 Infection

United States, Thailand, Uganda, South Africa
National Taiwan University Hospital
PharmaEssentia

Not yet recruiting

A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection

Hepatitis D

Taiwan
Chiayi Christian Hospital
Chi Mei Medical Hospital; Dalin Tzu Chi General Hospital; National Taiwan University... and other collaborators

Recruiting

TAF to Prevent HBV Reactivation in Cancer Patients

Hepatitis B Reactivation

Taiwan
National Institute of Allergy and Infectious Diseases...

Terminated

Emtricitabine/Tenofovir Alafenamide as Salvage ART

HIV

United States
Cwm Taf University Health Board (NHS)
Cardiff University; Imperial College London; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes

Diabetes Mellitus, Type 1 | SARS-CoV2 Infection

United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff University

Completed

Mycoplasma Species and the Genitourinary System

Sexually Transmitted Diseases, Bacterial

United Kingdom
Cwm Taf University Health Board (NHS)

Unknown

Clozapine Induced Weight Gain

Weight Gain | Pharmacogenetics | Antipsychotic Agents

United Kingdom
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Efficacy and Safety of TAF vs Other NAs in Patients With LVL

Chronic Hepatitis b | Cirrhosis Due to Hepatitis B

China
Cwm Taf University Health Board (NHS)
Cardiff University; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 / COVID-19

Covid19

United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff University

Completed

UROGEN WELL D-ONE : Evaluation of a Novel Diagnostic for Sexually Transmitted Bacterial Infections

Sexually Transmitted Diseases, Bacterial | Antimicrobial Resistance | Bacterial Urinary Tract Infection

United Kingdom
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Cwm Taf University Health Board (NHS)
PRIME Centre Wales

Unknown

Prompting And encouRaging Community Hydration Through EDucation (PARCHED)

Frailty

United Kingdom
Shanghai Public Health Clinical Center
Yunnan AIDS Care Center; Xixi Hospital of Hangzhou

Active, not recruiting

Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection

HIV-1-infection

China
Nanfang Hospital of Southern Medical University
Gilead Sciences; Tigermed Consulting Co., Ltd

Recruiting

Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic | Mother to Child Transmission

China
University of Colorado, Denver

Completed

The Cellular Pharmacology of F-TAF in Dried Blood Spots (TAF-DBS)

Healthy Volunteers

United States
Thomas Jefferson University
Gilead Sciences

Active, not recruiting

Entecavir to TAF Switch

Hepatitis B

United States
Janssen Scientific Affairs, LLC

Completed

A Study of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Evaluated as a Fixed Dose Combination Regimen in Participants Switching From an Integrase Inhibitor Who Have Experienced Rapid Weight Gain (DEFINE)

HIV-1

United States
Cwm Taf University Health Board (NHS)
Cardiff University

Completed

The Antibiotic Guardian Study- Clinical Evaluation of a Novel, Rapid Diagnostic for Gonorrhoea and Mycoplasma Infections. (Guardian)

Sexually Transmitted Diseases, Bacterial | Antibiotic Resistant Infection

United Kingdom
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

HBV | Chronic HBV Infections

China
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Negative for Hepatitis B e Antigen

HBeAg-negative Chronic Hepatitis B

Hong Kong, United States, United Kingdom, Canada, Australia, Spain, Taiwan, India, Japan, Poland, Romania, Russian Federation, Korea, Republic of, Italy, New Zealand, France, Turkey
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)

HBV | Chronic HBV Infections

China
BSN Medical GmbH

Completed

Observational Study of Clinical Performance of a Sterile, Bacteria-binding, Super-absorbent Wound Dressing

Wounds

United Kingdom
Kaohsiung Medical University Chung-Ho Memorial...

Recruiting

Tenofovir Alafenamide in HBV Related Decompensated Liver

HBV

Taiwan
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen

HBeAg-positive Chronic Hepatitis B

Hong Kong, Korea, Republic of, United States, Taiwan, United Kingdom, France, Australia, Spain, Bulgaria, Canada, India, Italy, Japan, New Zealand, Poland, Romania, Russian Federation, Singapore, Turkey
First People's Hospital of Hangzhou

Recruiting

Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women

Chronic Hepatitis b | Tenofovir Alafenamide Fumarate

China
Gilead Sciences

Completed

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Adults Who Are Virologically Suppressed

HIV-1-infection

United States, Puerto Rico, France, Germany, Austria, Canada
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in Human Immunodeficiency Virus (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

Spain, United States, Italy, Germany, United Kingdom, France, Australia, Puerto Rico, Canada, Belgium, Dominican Republic
ANRS, Emerging Infectious Diseases
Gilead Sciences; Ministry of Health, Thailand; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France. (SimpPrEP)

HIV/AIDS

France, Thailand
Gilead Sciences

Completed

Pharmacokinetic, Safety, and Efficacy of B/F/TAF in HIV-1 Infected, Virologically Suppressed, Pregnant Women in Their Second and Third Trimesters

HIV-1-infection

United States, Dominican Republic, Puerto Rico, Thailand
Carmen Hidalgo Tenorio
Gilead Sciences

Completed

Study of Bictegravir/Emtricitavine/Tenofovir Alafenamide in HIV-1 Infected naïve Patients Using Test and Treat Stategy Rapid-initiation Model of Care: BIC-NOW Clinical Trial (BIC-NOW) (BIC-NOW)

HIV Infections

Spain
National Institute of Allergy and Infectious Diseases...
CONRAD

Completed

Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVG) Administered Rectally

HIV Infections

United States
Yonsei University

Not yet recruiting

Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment

Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication
Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

Real-world Study Optimizing Nucleotide-analogues

Hepatitis B, Chronic

China
Gilead Sciences

Completed

Study to Evaluate the Pharmacokinetics of Tenofovir Alafenamide (TAF) in Adults With Normal Hepatic Function and Adults With Severe Hepatic Impairment

Hepatitis B Virus

United States, Germany, New Zealand
Gilead Sciences

Active, not recruiting

Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide (BIC-STaR)

HIV-1-infection

Canada
Gilead Sciences

Completed

Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide (B/F/TAF) (BIC-STaR)

HIV-1-infection

Israel
University of California, Los Angeles
Gilead Sciences

Completed

Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF) (UCLACAREMITO)

HIV/AIDS | Mitochondrial Alteration | Antiviral Toxicity | Antiviral Drug Adverse Reaction

United States
University Hospital Inselspital, Berne

Completed

TAF for HIV-HBV With Renal Dysfunction

HIV and Hepatitis B Coinfection

Switzerland
CONRAD
United States Agency for International Development (USAID); Eastern Virginia...

Completed

Safety, PK, and PD Study of a Vaginal Insert Containing TAF and EVG

Hiv | HSV

United States
Gilead Sciences

Not yet recruiting

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Tulika Singh, MD
Gilead Sciences

Recruiting

Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age

HIV-1-infection

United States
Technical University of Munich

Completed

Changes in Insulin Sensitivity in Healthy Volunteers Taking Tenofovir Alafenamide (TAF)-Containing Antiretroviral Medication (TAF-IR)

Insulin Resistance

Germany
University of Washington
University of Colorado, Denver; Gilead Sciences; Kenya Medical Research Institute

Completed

The Women TAF-FTC Benchmark Study

HIV Infections

Kenya
The HIV Netherlands Australia Thailand Research...
Police General Hospital; Faculty of Medical Sciences, Radboud University of... and other collaborators

Completed

Switching From Protease Inhibitor/Ritonavir to Generic Single Tablet Regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir

HIV

Thailand
Gilead Sciences

Recruiting

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

United States, Taiwan, Korea, Republic of, India, New Zealand, Belgium, Canada, Italy, Romania, Russian Federation, Hong Kong
Philadelphia Fight
Gilead Sciences

Completed

Validation of a Urine Assay to Measure Tenofovir Levels in Patients Taking Tenofovir Alafenamide

Hiv

United States
Göteborg University

Completed

Tenofovir Alafenamide Fumarate (TAF) Effect on Residual Intrathecal Immune Activation

HIV

Sweden

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