Search clinical trials for: Tofacitinib Oral

Total 17627 results

Hansoh BioMedical R&D Company

Not yet recruiting

Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis

Psoriatic Arthritis
Hospital Universitário Professor Edgard Santos
Instituto Gonçalo Muniz FIOCRUZ BA

Not yet recruiting

Tofacitinib Associated With Meglumine Antimoniate in Cutaneous Leishmaniasis (CLTofa23)

Cutaneous Leishmaniasis, American

Brazil
Pfizer

Recruiting

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Israel, Poland, Canada, Japan, Belgium, Spain, Hungary, Finland, France, Australia, United Kingdom, Germany, Italy, Sweden, Netherlands, Slovakia
National Institute of Dental and Craniofacial Research...

Recruiting

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome

Sjogren's Syndrome

United States
University Hospital, Lille
InBrain Pharma

Recruiting

Dopaminergic restauratIon by intraVEntriculaire Administration (DIVE)

Parkinson Disease

France
Charite University, Berlin, Germany

Recruiting

Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvement (PASTOR)

Spondylitis | Psoriatic Arthritis | Sacroilitis

Germany
Pfizer

Completed

A 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate

Arthritis, Rheumatoid

United States, Colombia, Korea, Republic of, Brazil, Taiwan, Mexico, India, Japan, Australia, Bulgaria, Ukraine, Canada, Poland, Czechia, Greece
Jinnah Hospital

Completed

Efficacy of Oral Tofacitinib in Moderate to Severe Alopecia Areata, Totalis and Universalis at Tertiary Care Hospital, Karachi.

Alopecia Areata | Alopecia Totalis | Alopecia Universalis

Pakistan
Services Institute of Medical Sciences, Pakistan

Completed

Efficacy and Safety of Oral Tofacitinib in the Treatment of Alopecia Areata

Extensive Alopecia Areata

Pakistan
Oregon Health and Science University
Pfizer

Completed

Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis

Sarcoidosis | Sarcoidosis, Pulmonary | Sarcoidosis Lung

United States
Tufts Medical Center
Pfizer

Terminated

Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus | Discoid Lupus Erythematosus

United States
Pfizer

Completed

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

Arthritis, Rheumatoid

Hong Kong, United States, Spain, Israel, Finland, Thailand, Turkey, Taiwan, Poland, Czechia, Malaysia, South Africa, Mexico, China, Australia, Slovakia, United Kingdom, New Zealand, Jordan, Canada, Netherlands, Brazil, Colombia, Puerto... and more
Pfizer

Completed

Open-Label Extension Study Of Tofacitinib In Psoriatic Arthritis (OPAL BALANCE)

Arthritis, Psoriatic

Belgium, United States, Canada, Spain, Australia, Taiwan, Czechia, Hungary, Germany, Mexico, Poland, Russian Federation, Slovakia, United Kingdom, Brazil, Bulgaria
University of Michigan
Pfizer

Completed

Evaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc) (TOFA-SSc)

Systemic Sclerosis | Scleroderma

United States
Pfizer

Completed

A Study to Demonstrate the Equivalence of the Tofacitinib Oral Solution to the Tablet Formulation in Healthy Participants.

Healthy

United States
Pfizer

Completed

A Study Evaluating The Efficacy And Safety Of CP-690,550 In Asian Subjects With Moderate To Severe Plaque Psoriasis

Psoriasis

Korea, Republic of, Taiwan, China
Pfizer

Completed

A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis

Psoriasis

United States, Denmark, Slovakia, Canada, Australia, Argentina, Bulgaria, Netherlands, United Kingdom, Brazil, Finland, Greece
Pfizer

Completed

Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors

Arthritis, Rheumatoid

Australia, United States, Austria, Germany, Ireland, Brazil, Spain, Taiwan, Belgium, Canada, France, Italy, Korea, Republic of, Puerto Rico
National Institute of Arthritis and Musculoskeletal...

Completed

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
Pfizer

Completed

Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTX (ORAL1069)

Arthritis, Rheumatoid

United States, Spain, Taiwan, Bulgaria, Czechia, Hungary, India, Korea, Republic of, Malaysia, Slovakia, Ukraine, Germany, Canada, Argentina, Australia, Thailand, Philippines, Puerto Rico, Brazil, Colombia, Chile, Costa Rica, Mexico, New... and more
Pfizer

Completed

A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis (OCTAVE)

Ulcerative Colitis

United States, Spain, Canada, Denmark, United Kingdom, France, Australia, Belgium, Israel, Germany, Korea, Republic of, Slovakia, Taiwan, Poland, New Zealand, Japan, Estonia, Hungary, Netherlands, Serbia, South Africa, Czech Republic and more
Pfizer

Completed

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Ankylosing Spondylitis

Korea, Republic of, United States, Spain, Taiwan, Canada, Czech Republic, Poland, Hungary, Germany, Russian Federation
Pfizer

Completed

A One-Year Study To Evaluate The Efficacy And Safety Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis

Psoriasis

United States, Canada, Poland, Serbia, Germany, Ukraine, Taiwan, Mexico, Colombia, Hungary, Puerto Rico
Pfizer

Completed

A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis

Psoriasis

United States, Canada, Germany, Colombia, Hungary, Japan, Mexico, Poland, Serbia, Taiwan, Ukraine
Pfizer

Completed

Co-Administration Of Methotrexate And CP-690,550

Rheumatoid Arthritis

United States
Pfizer

Completed

Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 Weeks

Rheumatoid Arthritis

United States, Germany, Italy, Spain, Canada, Belgium, Slovakia, Brazil, Mexico
Pfizer

Completed

A Phase 3 Study Comparing 2 Doses Of CP-690,550 And The Active Comparator, Humira (Adalimumab) Vs. Placebo For Treatment Of Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Costa Rica, Czech Republic, Germany, Croatia, Canada, Korea, Republic of, Spain, Bosnia and Herzegovina, Australia, Bulgaria, Mexico, Slovakia, Poland, Philippines, Chile, Denmark, Dominican Republic, Finland, T... and more
Pfizer

Completed

A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet Form

Healthy

Singapore
Pfizer

Completed

CP-690,550 And Oral Contraception Drug-Drug Interaction Study

Healthy

Belgium
Pfizer

Completed

A Study Of The Taste Of Different Oral Liquid Preparations Of CP-690,550 In Trained Adult Product Testers

Arthritis, Rheumatoid

United States
Elizabeth Austen Lawson

Not yet recruiting

Identifying Oxytocin Deficiency in Adults With Pituitary Disease

Oxytocin Deficiency | Arginine Vasopressin Deficiency
Akamis Bio

Not yet recruiting

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer (FORTRESS)

Locally Advanced Rectal Cancer (LARC)
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib

Drug Kinetics

Korea, Republic of
Novo Nordisk A/S

Not yet recruiting

A Research Study Looking at How the Compound NNC0487-0111 Works With Birth Control Pills and Affects Emptying of the Stomach in Women Not Able to Become Pregnant

Obesity

Canada
AbbVie

Not yet recruiting

Study of Oral Upadacitinib to Assess Change in Disease Activity and Adverse Events in Adult Participants With Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis
Azienda Ospedaliera di Perugia

Recruiting

Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery

Pain | Trismus | Edema Face | Extracting Own Teeth | Molar, Fourth

Italy
Institut de cancérologie Strasbourg Europe

Not yet recruiting

Evaluation of Two Methods of Administration of Photobiomodulation in the Context of the Prevention and Treatment of Mucositis Induced by Radiotherapy, During the Treatment of Head and Neck Cancers (RADIO-PBM)

Head and Neck Neoplasms

France
Qifu Li
Second Affiliated Hospital, School of Medicine, Zhejiang University; The First... and other collaborators

Recruiting

Finerenone for Patients With Primary Aldosteronism (FAIRY)

Primary Aldosteronism

China
Bradley Nindl
U.S. Army Medical Research and Development Command

Not yet recruiting

Adaptions and Resiliency to Multi-Stressor OpeRations (ARMOR)

Hypogonadism | Musculoskeletal Injury

United States
Fenerbahce University

Not yet recruiting

The Effect of Non-pharmacological Methods on Pain

Pain | Infant ALL | Preterm
Massachusetts General Hospital
International Centre for Diarrhoeal Disease Research, Bangladesh

Not yet recruiting

Correlates of Protection for Cholera (CoP)

Cholera
China Medical University Hospital

Recruiting

The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients

Respiratory Failure | Morality | Delayed Gastric Emptying | Organ Failure, Multiple | Indigestion

Taiwan
Zahra Nejati
Kurdistan University of Medical Sciences; Hady Mohammadi, Director of oral... and other collaborators

Not yet recruiting

Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction

Temporomandibular Joint Disorders | Molar, Third | Dry Socket | Coenzyme Q10
Hospital Israelita Albert Einstein
University of Sao Paulo

Recruiting

Effect of Toothbrushing Without Chlorhexidine on Oral Hygiene Indices in Patients With Orotracheal Intubation

Oral Hygiene | Intensive Care | Chlorhexidine

Brazil
C K S Teja Institute Of Dental Sciences & Research

Not yet recruiting

Comparative Evaluation of SMART Hall Technique vs. Conventional SS Crown in Primary Molars: A Randomized Clinical Trial (RCT)

Pain | Plaque, Dental | Caries,Dental | Gingival Bleeding

India
Anhui Medical University

Not yet recruiting

Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases

Mitochondrial Diseases
Hacettepe University

Not yet recruiting

Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions (ZTE-DENTAL)

Edentulous Alveolar Ridge

Turkey
University of Leeds
The Leeds Teaching Hospitals NHS Trust

Not yet recruiting

PROSpECT-PRIOR-2-CHEMO: PRIOR Dental Intervention Before Chemo to Reduce Chemotherapy Complications

Periodontitis | Febrile Neutropenia | Oncology | Myeloma | Oral Mucositis

United Kingdom
Cairo University

Recruiting

Radiographic and Histological Assessment of Autogenous Onlay Block Versus Cortical Shell on Anterior Maxilla

Alveolar Bone Loss

Egypt

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