Search clinical trials for: Tuberculosis, PA-824

Total 4725 results

Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) (CL-009)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Study in Two Panels of Healthy Adult Participants to Assess Single-Dose Immediate-Release and Single-Dose Dispersible Formulations of Pretomanid

Multi-drug Resistant Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Single-Dose Study to Evaluate the PKs of Pretomanid in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Renal Impairment | Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Pretomanid in Adults With Hepatic Impairment

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects. (CL-004)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-003)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)

Pulmonary Tuberculosis
Global Alliance for TB Drug Development

Active, not recruiting

A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteers (PaSEM)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Georgia, South Africa
Bayer

Completed

Safety and Efficacy of BAY94-9027 in Previously Treated Male Children With Haemophilia A

Hemophilia A

Belgium, New Zealand, Netherlands, Greece, United Kingdom, Austria, United States, Italy, Romania, Bulgaria, Canada, Israel, Poland, Lithuania, Norway, Argentina, Spain
National Institute of Allergy and Infectious Diseases...

Completed

Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteers

Tuberculosis

United States
Johns Hopkins University
University of Cape Town

Completed

Assessing PA-824 for Tuberculosis (the APT Trial)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) (NC-003)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)

Pulmonary Tuberculosis

South Africa
University of Delaware

Completed

Cardiovascular Effects of High-Intensity Interval Training (HIIT)

Healthy Sedentary Adults With BP <140/90

United States
Global Alliance for TB Drug Development

Completed

A Phase 3 Study Assessing the Safety and Efficacy of Bedaquiline Plus PA-824 Plus Linezolid in Subjects With Drug Resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Tanzania, Georgia, Russian Federation, Brazil, Malaysia, Philippines, South Africa, Uganda
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Global Alliance for TB Drug Development

Completed

A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. (NC-005)

Tuberculosis

Tanzania, South Africa, Uganda
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Global Alliance for TB Drug Development

Recruiting

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis

Drug Sensitive Tuberculosis | Pulmonary Tuberculosis | Pulmonary TB

Philippines, South Africa, Tanzania, Georgia, Uganda
Global Alliance for TB Drug Development

Completed

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Pulmonary Tuberculosis

Tanzania, South Africa
Rush University Medical Center
University of Illinois at Chicago; Michigan State University

Active, not recruiting

Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women

Physical Activity

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Shortening Treatment by Advancing Novel Drugs (STAND)

Tuberculosis, Pulmonary, Drug Sensitive | Tuberculosis, Pulmonary, Multi Drug-resistant

South Africa, Zambia, Georgia, Philippines, Kenya, Malaysia, Tanzania, Uganda
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Sussex; Ministry... and other collaborators

Completed

Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial (PRACTECAL-PRO)

Multidrug Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Liverpool; Ministry... and other collaborators

Completed

Economic Evaluation of New MDR TB Regimens (PRACTECAL-EE)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculoses | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Hui-Sheng Chen

Terminated

Argatroban Plus r-tPA for Posterior Circulation Infarction（AR-PCI）

Argatroban, Rt-PA

China
Federal University of São Paulo

Completed

Efficacy/Safety of Antibiotic Steroid Combination in Prevention of Post Operative Inflammation in LASIK Surgery

Post Lasik Surgery Inflammation

Brazil
Federal University of São Paulo

Completed

Efficacy/Safety of Antibiotic Steroid Combination in Prevention of Postoperative Inflammation in Cataract Surgery

Inflammation Following Cataract Surgery

Brazil
Rambam Health Care Campus

Completed

The Effect Methylphenidate Hydrochloride on Pain and Auditory Sensitivity in Healthy Subjects

Pharmacological Action (PA)

Israel
Bayer

Completed

Human Photoallergy Test (824/2016)

Sunscreening Agents

United States
Recordati Rare Diseases
Target PharmaSolutions, Inc.

Recruiting

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

Propionic Acidemia | Methylmalonic Acidemia | Hyperammonemia

United States
Istituti Clinici Scientifici Maugeri SpA
University of Bologna

Completed

Temporal Disorders in Left and Right Brain-Damaged Patients

Brain Disease

Italy
Ben-Gurion University of the Negev

Completed

Diet and Body Composition (CENTRAL)

Obesity

Israel
Chinese University of Hong Kong

Completed

Using Night-time Blood Pressure to Treat Hypertension

Hypertension

Hong Kong
Hospices Civils de Lyon
Institut National de la Santé Et de la Recherche Médicale, France; Centre National... and other collaborators

Recruiting

Prismatic Adaptation for Rehabilitation of Postural Imbalance After Stroke (PEQUIE)

Chronic Right Supratensorial Stroke Patients

France
Andon Health Co., Ltd

Completed

Blood Pressure Monitor Clinical Test (Cuff Range: 22 Cm-42cm)

Blood Pressure
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate Efficacy of Different Natural Ingredients in Improving Gut Health in Adults With Leaky Gut.

Gut Health

India
St. Justine's Hospital

Recruiting

Dynamo: a Tailored Lifestyle Promotion Intervention Among Pediatric Patients With Cardiometabolic Risk Factors (CIRCUIT)

Obese

Canada
University of Michigan

Completed

Social Media Intervention - Physical Activity

Cannabis Use

United States
University of Texas at Austin

Terminated

Evaluation of AVANCE Fathers in Action/Padres Activos Fatherhood Program (AVANCE)

Fathers
Andon Health Co., Ltd

Completed

Blood Pressure Monitor Clinical Test (Cuff Range: 22 Cm-36cm)

Blood Pressure
Andon Health Co., Ltd

Completed

Clinical Test for Armed-used Blood Pressure Monitor With Preformed Cuff

Blood Pressure
Andon Health Co., Ltd

Completed

Wrist-used Blood Pressure Monitor Clinical Test (Cuff Range: 14cm-25cm) (WBPMCT)

Blood Pressure

China
Andon Health Co., Ltd

Completed

Clinical Test for Armed-used Blood Pressure Monitor With Preformed Cuff(Monitor When Being Inflated)

Blood Pressure
Andon Health Co., Ltd

Completed

Blood Pressure Monitor Clinical Test (Cuff Range: 13.5 Cm-22cm)

Blood Pressure
Duke University

Completed

Engaging African American Older Adults With Arthritis in a Physical Activity Intervention

Osteoarthritis, Knee | Osteoarthritis, Hip

United States

Search clinical trials for: Tuberculosis, PA-824

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