Search clinical trials for: Vaccines, Synthetic

Total 1314 results

Myovant Sciences GmbH

Completed

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Uterine Leiomyoma

United States, Italy, Poland, Czechia, Hungary, South Africa, Brazil, Chile
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020

Enteritis Caused by Radiation

United States
Myovant Sciences GmbH

Completed

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Belgium, Czechia, South Africa, Chile, Brazil, Hungary, Poland
Myovant Sciences GmbH

Completed

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Italy, Poland, Brazil, South Africa, United Kingdom
Botanix Pharmaceuticals

Completed

Evaluation of BTX 1503 in Patients With Moderate to Severe Acne Vulgaris

Acne Vulgaris

United States, Australia
Soligenix

Completed

FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides)

Cutaneous T-Cell Lymphoma

United States
Sebela Women's Health Inc.
Synteract, Inc.

Completed

Evaluation of the Efficacy and Safety of LevoCept

Contraception

United States
Emory University
Novartis

Terminated

Phase II Study of Everolimus Beyond Progression

Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast Cancer

United States
Fudan University

Terminated

Metformin Plus Megestrol Acetate as a Fertility-sparing Treatment in Patients With Atypical Endometrial Hyperplasia

Atypical Endometrial Hyperplasia

China
HRA Pharma

Terminated

A Study of Oral Contraception Under Simulated OTC Conditions (OPTION)

Contraception

United States
Norton Healthcare

Completed

Use of Norethindrone Acetate for Management of Bleeding Associated With the Etonogestrel Contraceptive Implant

Etonogestrel Contraceptive Implant, Bothersome Bleeding

United States
University Hospital, Toulouse

Completed

Patient Satisfaction With the Management of a Stopped Pregnancy in the First Trimester (MYFEFACY)

Pregnancy Loss, Early

France
Institut Cancerologie de l'Ouest

Completed

Feasibility of MRI Workflow Alone in External Radiotherapy for the Treatment of Brain and Prostate Tumors (PRIS)

Prostate Cancer | Brain Cancer

France
Washington University School of Medicine
Susan G. Komen Breast Cancer Foundation

Withdrawn

Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Triple-Negative Breast Cancer
University Hospital, Toulouse

Completed

Comparison of Two Strategies of Glucocorticoid Withdrawal in Rheumatoid Arthritis Patients (STAR)

RheumatoId Arthritis

France
Medstar Health Research Institute

Completed

Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation (MMSAP)

Induced Abortion
Prof Mags Beksinska

Completed

Functional Performance and Acceptability Study of Synthetic Nitrile, and Latex Graphene, Compared to Standard Latex Male Condom

Functional Performance

South Africa
Far Eastern Memorial Hospital

Completed

The Impact of Hormone Therapy on Lower Urinary Tract Symptoms, Sexual Function and Psychosomatic Disorder

Menopausal Syndromes

Taiwan
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Role of Vitamin D3 Supplementation With Conventional Synthetic Disease Modifying Antirheumatic Drugs(csDMARD) in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Bangladesh
Organon and Co

Completed

Effects on Hemostasis, Lipids, Carbohydrate Metabolism, Adrenal & Thyroid Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG-EE (292004)(COMPLETED)(P05764)

Contraception
Novartis Pharmaceuticals

Completed

A Drug-Drug Interaction Study to Assess the Effect of Trametinib on the Pharmacokinetics of an Oral Contraceptive in Female Patients With Solid Tumors

Solid Tumors

Netherlands, Spain, United Kingdom, United States, Belgium
Corcept Therapeutics

Completed

A 4-week Study of Mifepristone in the Prevention of Risperidone-induced Weight Gain in Healthy Male Volunteers

Healthy

India
Organon and Co

Completed

Post-marketing, Observational Study to Confirm the Safety and Efficacy of MARVELON (Study P06083)

Contraception
Organon and Co

Completed

Efficacy of Tibolone Versus Transdermal E2/NETA on Sexual Function in Naturally Postmenopausal Women (P06089)

Sexual Dysfunction
Organon and Co

Completed

A Bioequivalence Study of IMPLANON and Radiopaque IMPLANON (34528)(P05720)

Contraception
Organon and Co

Completed

An Explorative Trial to Explore the Safety, Acceptability and Vaginal Bleeding Pattern of Three Etonogestrel-releasing Medicated Intrauterine Systems (Study P06060)

Contraception
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)

Contraception

South Africa, Austria, Costa Rica, Denmark, Finland, Germany, Hungary, Italy, Mexico, Netherlands, Norway, Peru, Poland, Sweden
Organon and Co

Completed

A Trial in Healthy Female Subjects to Compare the Pharmacokinetics of Ethinyl Estradiol of NuvaRing®, a Contraceptive Patch (EVRA(TM)) and an Oral Contraceptive (Microgynon® 30) (Study 34237 (P06650)) (COMPLETED)

Contraception
Organon and Co

Completed

Performance and Safety of Vaginal Ring Applicator in Healthy Females (MK-8342A-063)

Contraception: Optional Applicator for Insertion of Vaginal Ring
Organon and Co

Completed

Predictive Factors for Ovarian Stimulation Using a Fixed Daily Dose of 200 IU Recombinant FSH (Study 142003)(P05696) (Xpect)

Infertility
Organon and Co

Completed

An Open-label, Single Center Trial to Assess the Pharmacokinetics, Pharmacodynamics and Safety of Org 36286 (P07004)

Infertility
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

CD19-Synthetic T Cell Antigen Receptor(STAR)-T in B-cell Malignancies Patients

B Cell Malignancy

China
Viriom

Completed

Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs

HIV-1-infection

Russian Federation
Teva Branded Pharmaceutical Products R&D, Inc.
FHI 360

Completed

A Study to Evaluate Injection Pain and Local Tolerability Following Subcutaneous (SC) Administration of TV-46046

Contraception

Dominican Republic
BioGend Therapeutics Co.Ltd

Completed

BiPhasic Cartilage Repair Implant (BiCRI) IDE Clinical Trial - Taiwan

Chondral or Osteochondral Lesion of Medial Femoral Condyle | Chondral or Osteochondral Lesion of Lateral Femoral Condyle | Chondral or Osteochondral Lesion of Trochlea

Taiwan
Karolinska Institutet

Completed

BRCA1/2 and Effect of Mifepristone on the Breast

Women With Mutations in the Breast Cancer Susceptibility Genes BRCA1,2

Sweden
University of California, Davis
Rockefeller University

Completed

Amino Acid Profile and Muscle Protein Synthetic Response to Consuming Meat or Plant-based Alternatives

Healthy

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Studying the Performance of OCT C-scan in the Screening for Retinopathy Related to Synthetic Antimalarials (PERFOCTAPS)

Maculopathy | Toxicity, Drug

France
University of Colorado, Denver

Completed

Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women

Cardiovascular Disease | Cognitive Impairment | Endothelial Dysfunction | Executive Dysfunction

United States
University Hospital, Geneva

Terminated

Does Oral Desogestrel Prior to Insertion of the Etonogestrel Subdermal Implant Improve Continuation Rate at One Year?

Contraception | Progestogen Adverse Reaction
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

HIV Infections | Tuberculosis

United States, South Africa, Malawi, Brazil, Kenya, Thailand, Botswana
University of Pittsburgh

Completed

Quantification of Immune Cells in Women Using Contraception (CHIC II) (CHIC-II)

HIV | Contraception | Immune Cells (Mucosal and Systemic)

United States
Rebecca Hunt
MaineHealth

Terminated

Postplacental Mirena IUD Insertion and Estimating Expulsion Rates.

Estimating Rates of Expulsion
Columbia University

Completed

Pilot Study of Femring Estrogen Supplementation During Depo-Provera Initiation

Metrorrhagia

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate Ovarian Follicular Activity and Hormone Levels for DR-102 Compared to Two 28-Day Oral Contraceptives

Oral Contraceptive | Follicle Development | Ovarian Follicle | Follicle Count | Follicle Size

United States
Shannon K. Laughlin-Tommaso
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids

Uterine Fibroids | Menorrhagia | Heavy Menstrual Bleeding

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Multinational Study to Evaluate the Effects of a 28-Day Oral Contraceptive on Hemostatic Parameters in Healthy Women

Oral Contraceptive | Hemostasis

Germany, Israel, Italy, Spain
Assistance Publique - Hôpitaux de Paris

Completed

Mesh Reinforcement During Temporary Stoma Closure After Sphincter-Saving Rectal Cancer Surgery (MEMBO)

Incisional Hernia After Diverting Stoma Closure

France
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate Hormone Patterns and Ovarian Follicular Activity With DR-1021

Healthy

United States
University of Malaya

Completed

Clinical and Metagenomic Investigation of Antimicrobial Peptide Gel in Periodontal Treatment.

Periodontitis

Malaysia

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