Search clinical trials for: Vascular disrupting agent

Total 217123 results

Australasian Gastro-Intestinal Trials Group

Completed

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer (MODULATE)

Colorectal Cancer Metastatic

Australia
Novartis Pharmaceuticals

Terminated

ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer (ATRACT-1)

Non-Small Cell Lung Cancer

United States, Greece, Hong Kong, Taiwan, Argentina, Germany, United Kingdom, Singapore, Italy, Spain, France, Korea, Republic of, Netherlands, Brazil, Canada, Turkey, China, New Zealand, Hungary, Poland, Australia, Japan, Israel, Bel... and more
Novartis Pharmaceuticals

Terminated

A Study of ASA404 or Placebo in Combination With Docetaxel in Second-line Treatment for (Stage IIIb/IV) Non-small Cell Lung Cancer (ATTRACT-2)

Non-Small Cell Lung Cancer

United States, Germany, Belgium, Italy, France, Canada, Hungary, Poland, Switzerland, Spain
Novartis Pharmaceuticals

Completed

An Open-label, Phase I Trial of Intravenous ASA404 Administered in Combination With Paclitaxel and Carboplatin in Japanese Patients With Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

Japan
Hoosier Cancer Research Network
University of Sydney; Bionomics Limited; Australia New Zealand Gynaecological...

Withdrawn

BNC105P Combination Study in Partially Platinum Sensitive Ovarian Cancer Patients

Ovarian Cancer

United States, Australia, New Zealand
Chong Kun Dang Pharmaceutical
Seoul National University Hospital

Completed

Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers

Unspecified Adult Solid Tumor, Protocol Specific

Korea, Republic of
Mateon Therapeutics

Completed

Study Evaluating the Safety and Response of Fosbretabulin in Asian Patients With Polypoidal Choroidal Vasculopathy (PCV)

Polypoidal Choroidal Vasculopathy

United States, Hong Kong, Korea, Republic of, Singapore, Taiwan
Mateon Therapeutics
Cancer Research UK

Completed

Safety Study of OXi4503 (a Vascular Disrupting Agent) Given by 3 x Weekly Intravenous Infusions to Patients With Advanced Solid Tumors

Solid Tumors

United Kingdom
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors

Tumors

United Kingdom
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretasatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Hepatic Tumor Burden (OXi4503)

Neoplasm Metastasis

Australia
Nereus Pharmaceuticals, Inc.

Completed

Phase 1/2 Study of Vascular Disrupting Agent NPI-2358 + Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer

Cancer

United States, Australia, India, Chile, Brazil, Argentina
Nereus Pharmaceuticals, Inc.

Completed

Study of the Vascular Disrupting Agent NPI-2358 in Patients With Advanced Solid Tumors or Lymphoma

Cancer

United States
Antisoma Research

Completed

Study of AS1404 With Docetaxel in Patients With Hormone Refractory Metastatic Prostate Cancer

Prostate Cancer

United States
Peking University First Hospital

Recruiting

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis (FAIR)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Dose Optimization of Caffeine for HIE

Hypoxic-Ischemic Encephalopathy

United States
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
Mersin Medicalpark Hastanesi

Not yet recruiting

Does Verapamil Given Orally Prevent Radial Artery Spasm During Transradial Coronary Angiography

Radial Artery Spasm
BioNTech SE

Not yet recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

Small-cell Lung Cancer | Extensive-stage Small-cell Lung Cancer
Institut National de la Santé Et de la Recherche...

Recruiting

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain (APEDOC)

Stroke

France
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (EMBARQ-CSU1) (EMBARQ-CSU1)

Chronic Spontaneous Urticaria
Jun Tao

Recruiting

α-ketoglutarate in Patients With Hypertension (AKGHTN)

Hypertension

China
Washington University School of Medicine

Not yet recruiting

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Kaposi Sarcoma

United States
University of Zurich

Recruiting

Cerebrovascular Disease: Quality of Life (CODE: QoL) (CODE:QoL)

Cerebrovascular Disorders | Quality of Life | Stress | Transient Ischemic Attack | Caregiver Burden | Sexual Behavior | Stroke, Acute | Intracerebral Hemorrhage | Incontinence, Urinary | Cortisol Excess

Switzerland
University of Wisconsin, Madison
Fogarty International Center of the National Institute of Health

Not yet recruiting

Community Health Worker-led Hypertension Management

Hypertension
Ottawa Hospital Research Institute

Not yet recruiting

Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)

Venous Thromboembolism

Canada
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
Medical University of Vienna

Recruiting

Comparing Anticoagulation Strategies Using UFH, Argatroban and LMWH for ECMO Support (CASUAL-ECMO)

Respiratory Insufficiency | Bleeding | Thromboembolism | Circulatory Failure

Austria
Yinyi(Liaoning) Biotech Co., Ltd.

Not yet recruiting

Bingo Drug-eluting Balloon Versus a Drug-eluting Stent for Coronary Bifurcation Lesions

Coronary Artery Disease
Hoffmann-La Roche
Shanghai Roche Pharmaceutical Co., Ltd

Recruiting

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
Universidade do Porto
University of Oxford; University of Edinburgh

Not yet recruiting

Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography (SAFE-CT)

Coronary Artery Disease | Coronary Atheroscleroses

Portugal
Opna Bio LLC

Not yet recruiting

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
The Second Hospital of Nanjing Medical University

Recruiting

Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD

Type A Aortic Dissection

China
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
University of Thessaly

Not yet recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair (CoFA-TAAA)

Platelet Activation | Thoraco-abdominal Aortic Aneurysm Repair | Coagulation Factors Alterations

Greece
Radboud University Medical Center
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Maasstad Hospital

Not yet recruiting

Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm (EDIT-CAS)

Coronary Spasm

Netherlands
Thrombolex, Inc.

Not yet recruiting

The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism

Pulmonary Embolism
China National Center for Cardiovascular Diseases

Recruiting

Potts-shunt for the Treatment of Pediatric Patients With Severe Pulmonary Hypertension

Pulmonary Artery Hypertension

China
Chong Kun Dang Pharmaceutical

Recruiting

Efficacy and Safety of Telmisartan Compared With Losartan

Hypertension | Diabetic Nephropathies

Korea, Republic of
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
Region Skane
The George Institute for Global Health, Australia

Not yet recruiting

International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER)

Stroke | Intraventricular Hemorrhage | Cerebrovascular Disease | Intracerebral Hemorrhage | Intracerebral Haemorrhage

Australia, Sweden
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study (IVORY-FINALE)

Acute Coronary Syndromes

United Kingdom
Ewha Womans University Seoul Hospital

Not yet recruiting

Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.

Stroke | Atherosclerosis
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
S. Tony Wolf

Not yet recruiting

Effects of an Antioxidant Supplement on Blood Vessel Health

Healthy
Wake Forest University Health Sciences

Not yet recruiting

Team Based Equity Conscious Telemedicine Approach to Hypertension

Hypertension

United States
University of Alberta
Heart and Stroke Foundation of Canada

Not yet recruiting

Fish Oil, Metformin and Heart Health in PCOS

Cardiovascular Disease | PCOS | Cardiac Hypertrophy | Atherosclerotic Cardiovascular Disease | Atherosclerotic Plaque
Alnylam Pharmaceuticals

Not yet recruiting

A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension

Mild to Moderate Hypertension
Translumina GmbH
EVAMED

Recruiting

Evaluation of the Vivo Isar Stent System in Routine Clinical Practice (CELEBRITY)

Artery Coronary Stenosis

France
Zhejiang Chinese Medical University

Recruiting

A Randomized Controlled Study on the Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture

Postherpetic Neuralgia | Electroacupuncture | Infrared Thermography

China

Search clinical trials for: Vascular disrupting agent

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