Search clinical trials for: amino acid metabolism

Total 53840 results

Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Peking University First Hospital

Not yet recruiting

Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

Type 2 Diabetes
Murdoch Childrens Research Institute

Not yet recruiting

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. (PEGASUS)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

Australia
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Rigshospitalet, Denmark

Recruiting

Whole Body Metabolism in Children Before and After Treatment of CNS Tumor

CNS Tumor, Childhood

Denmark
Fundació Eurecat
Centre de Diagnosi per la Imatge; Instituto de Investigación Biomédica de Girona... and other collaborators

Not yet recruiting

Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity (FATHIS+)

Visceral Obesity | Non-alcoholic Fatty Liver | Postmenopausal

Spain
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Functional Impairment in Albinism (PLAIB)

Albinism, Ocular
Rigshospitalet, Denmark

Not yet recruiting

Evaluating the Efficacy and Safety of Large Neutral Amino Acids in the Treatment of Classical Phenylketonuria

Brain Diseases | Genetic Diseases, Inborn | Metabolism, Inborn Errors | Brain Diseases, Metabolic | Phenylketonurias | Brain Diseases, Metabolic, Inborn | Amino Acid Metabolism, Inborn Errors | Metabolic Disease

Denmark
NGGT (Suzhou) Biotechnology Co., Ltd.

Not yet recruiting

AAV Gene Therapy Clinical Study in Adult Classic PKU

Phenylketonurias
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
BioMarin Pharmaceutical

Recruiting

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

Phenylketonuria (PKU)

United States
Azienda Ospedaliero Universitaria Maggiore della...

Recruiting

Phenotyping Patients With Type 2 Diabetes Mellitus and Cancer (TCPT2023)

Diabetes Mellitus, Type 2 | Cancer

Italy
PTC Therapeutics

Recruiting

A Study of Sepiapterin in Participants With Phenylketonuria (PKU) (EPIPHENY)

Phenylketonuria

United States
metaX Institut fuer Diatetik GmbH
Great Ormond Street Hospital for Children NHS Foundation Trust; Birmingham...

Not yet recruiting

Acceptability/Tolerance of Protein Substitutes in Tablet Form for the Dietary Management of Rare Aminoacidopathies (ZeroMinisMR)

Alkaptonuria | Homocystine; Metabolic Disorder | Tyrosinemia, Type I | Tyrosinemia, Type II | Tyrosinemia, Type III | MSUD (Maple Syrup Urine Disease)
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Announcement of Rare Metabolic Diseases in Systematic Newborn Screening: the Phenylketonuria Experience. (ANNPHE)

Phenylketonuria

France
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Recruiting

Evaluation of a Genetically Determined Personalized Approach in Prescribing Biologically Active Substances in Patients With Elevated Blood Homocysteine Levels. (PERBIO-HC)

Hyperhomocysteinemia

Russian Federation
iECURE, Inc.

Recruiting

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency (OTC-HOPE)

Urea Cycle Disorders, Inborn | Ornithine Transcarbamylase Deficiency | Ornithine Transcarbamylase Deficiency Disease | Ornithine Carbamoyltransferase Deficiency (Disorder)

United Kingdom
Travere Therapeutics, Inc.

Recruiting

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment (HARMONY)

Homocystinuria

United States
Swedish Orphan Biovitrum

Recruiting

A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients

Hereditary Tyrosinemia, Type I

China
Shanghai Vitalgen BioPharma Co., Ltd.

Recruiting

A Study to Evaluate the Tolerability, Safety and Efficacy of VGM-R02b

Glutaric Acidemia Type I | Glutaric Aciduria Type I

China
University Hospital, Grenoble

Recruiting

Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer (AMINOCANCER)

Ovarian Cancer

France
University of Toronto

Recruiting

Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States (BTLP)

Physical Inactivity | Resistance Exercise | Amino Acids | Dietary Protein

Canada
ModernaTX, Inc.

Recruiting

A Dose-finding Study to Evaluate mRNA-3210 in Participants With Phenylketonuria

Phenylketonuria

United States, Australia
Assistance Publique - Hôpitaux de Paris

Recruiting

Peripheral Serotonin and Albinism (SEPIAs)

Oculocutaneous Albinism

France
Region Stockholm
Amgen

Not yet recruiting

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Acute Metabolic Effects of Evolocumab and Atorvastatin
University of Aarhus

Recruiting

The Effect of Arginine on Biofilm Composition, Architecture and Metabolism

Dental Caries | Microbial Colonization | Dental Plaque

Denmark
University of Toronto

Recruiting

Oral Contraceptive vs Menstrual Cycle Ex Vivo Model (OCEV)

Contraceptives, Oral | Sex Hormone

Canada
University of Trieste

Recruiting

Biomarkers in the Diagnosis and Prognosis of NAFLD

Obesity | Diabetes Mellitus, Type 2 | NAFLD | Liver Fibrosis

Italy
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
First Affiliated Hospital Bengbu Medical College

Recruiting

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Phenylketonurias

China
Maastricht University Medical Center
DSM Food Specialties

Recruiting

Impact of Canola Protein Processing on Plasma Amino Acid Responses (CANOLAA)

Protein Metabolism Disorder

Netherlands
University Hospital, Basel, Switzerland

Recruiting

Oxytocin Substitution Therapy in Patients With Central Diabetes Insipidus (OxyTUTION)

Central Diabetes Insipidus (cDI)

Switzerland
Lumos Diagnostics
Aptatek Biosciences

Recruiting

PheCheck Feasibility Study

Phenylketonurias

United States
Vitaflo International, Ltd
Birmingham Women's and Children's NHS Foundation Trust

Recruiting

Evaluation of PKU UP (PKU UP)

PKU

United Kingdom
Mayo Clinic

Not yet recruiting

Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus

Type 1 Diabetes

United States
Sanofi

Recruiting

A Phase 1/Phase 2 Open-label Study to Evaluate the Safety, Tolerability, and Efficacy of a Single Intravenous Administration of SAR444836 in Adult Participants With Phenylketonuria

Phenylketonuria

Turkey, United States
University of Guelph
McMaster University

Recruiting

PKU Carriers Trial (Pilot Study): Impact on Cognition, Mental Health, Blood Pressure and Metabolism

Autosomal Recessive Disorder (Genetic Carriers of PKU)

Canada
Institut National de la Santé Et de la Recherche...

Recruiting

FARD (RaDiCo Cohort) (RaDiCo-FARD) (FARD)

Neurofibromatosis Type 1 | Ichthyosis | Ectodermal Dysplasia | Albinism | Pemphigus | Mucous Membrane Pemphigoid | Inherited Epidermolysis Bullosa | Palmoplantar Keratoderma | Incontinentia Pigmenti

France
Children's Hospital of Fudan University
Hedu Biotechnology (Shanghai) Co., LTD

Recruiting

Efficacy and Safety of Orally Administered Engineered Probiotics (CBT102-A) for the Treatment of Children With Phenylketonuria

Phenylketonuria

China
Neoped - Centru de Pediatrie
University of Medicine and Pharmacy "Victor Babes" Timisoara; West University...

Not yet recruiting

Cardio-Metabolic Risk Evaluation in Overweight and Obese Children (CardMetSOb)

Atherosclerosis | Metabolic Syndrome | Pediatric Obesity | Nonalcoholic Fatty Liver | Cardiometabolic Syndrome | Psychology

Romania
West Kazakhstan Medical University

Recruiting

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Ornithine Transcarbamylase Deficiency | Biotinidase Deficiency | Citrullinemia | Glutaric Acidemia Type II | Argininosuccinic Aciduria | Maple Syrup Urine Disease | Primary Carnitine Deficiency | Homocystinuria | Carnitine Palmitoyltransferase II Deficiency | Arginase Deficiency | Very Long-chain Acyl-CoA... and other conditions

Kazakhstan
University Hospital, Grenoble

Recruiting

Evaluation of Capillary Blood Collection Devices (Mitra® and HemaPEN®) (MitrAlanine)

Metabolic Diseases | Phenylketonuria

France
Klinikum Nürnberg

Recruiting

A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease. (DapaBalci-Leap)

Chronic Renal Failure | Mechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis

Germany, France
Maastricht University

Not yet recruiting

Role of BCAA in Glucose Homeostasis (NaPB2)

Type 2 Diabetes
University of Toronto
Dairy Management Inc.

Recruiting

The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth (PBS)

Dietary Proteins | Indicator Amino Acid Oxidation

Canada
APR Applied Pharma Research s.a.

Recruiting

Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.

Phenylketonurias

Italy
Washington University School of Medicine
Children's Discovery Institute; Polaris Pharmaceuticals, Inc.

Not yet recruiting

ADI-PEG20, Obesity and Prediabetes

Obesity | PreDiabetes

United States
BioMarin Pharmaceutical

Recruiting

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace) (PALace)

Phenylketonuria (PKU)

United States, Germany, Italy
Karolinska Institutet

Recruiting

Arginase Inhibition in Type 1 and Type 2 Diabetes Mellitus

Type 1 Diabetes | Type 2 Diabetes

Sweden

Search clinical trials for: amino acid metabolism

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