Search clinical trials for: anaplastic lymphoma kinase (ALK)

Total 19187 results

ALK-Abelló A/S
Quantify Research

Active, not recruiting

Comparative Real World Effectiveness of SQ Sublingual Immunotherapy (SLIT)-Tablets vs. Controls in Allergic Rhinitis and Asthma

Asthma | Allergy | Allergic Rhinitis

Denmark
ALK-Abelló A/S

Completed

A Dose-response Evaluation of ALK (the Sponsor) Tree Allergy Immunotherapy Tablet

Birch Pollen Allergy

Finland, Netherlands
ALK-Abelló A/S
Ernst & Young

Recruiting

The Effect of Allergic Rhinitis on Educational Outcomes

Allergic Rhinitis

Denmark
ALK-Abelló A/S

Completed

Impact of AIT on Allergic Rhinitis and Asthma

Allergy | Respiratory Disease

Denmark
ALK-Abelló A/S
Ergomed; ACM Pivotal Global Central Laboratory

Completed

House Dust Mite Treatment of Asthma. The MITRA Trial House Dust Mite Treatment of Asthma (MITRA)

Asthma

Germany
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital

Completed

Safety and Efficacy Study of Intralymphatic Allergen-specific Immunotherapy

Allergic Rhinitis

Sweden
Karolinska Institutet

Completed

The Safety and Efficacy of Intralymphatic Immunotherapy in Pollen Allergic Adolescents and Young Adults With Asthma

Asthma | Allergy | Rhinitis
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital; Sodra Alvsborgs Hospital

Completed

Intralymphatic Immunotherapy in Increasing Doses, After Subcutaneous Immunotherapy

Rhinitis, Allergic

Sweden
Bispebjerg Hospital
ALK-Abelló A/S

Completed

Immunological Comparison of AIT and SCIT Immunotherapy Against Grass Pollen

Allergic Rhinitis Due to Grass Pollens

Denmark
ALK-Abelló A/S

Completed

A Phase III Trial Assessing the Pharmacodynamic Effect and the Tolerability of Grazax Treatment

Grass Pollen Allergy

Denmark
Lars Olaf Cardell

Completed

Is Intralymphatic Allergen Immunotherapy Effective and Safe?

Allergic Rhinitis Due to Grass Pollen

Sweden
University of Milano Bicocca

Completed

Pilot Study of Crizotinib in Relapsed ALK+ Lymphomas

Anaplastic Large Cell Lymphoma, ALK-Positive

Italy
The S.N. Fyodorov Eye Microsurgery State Institution

Completed

Femtosecond Laser-assisted Anterior Lamellar Keratoplasty

Corneal Opacity | Keratoconus
ALK-Abelló A/S

Completed

Tolerability of Grazax-R in Children

Allergy

Germany
ALK-Abelló A/S

Completed

Tolerability of ALK Grass Tablet in Children

Allergy

Spain
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Study of Exosome EML4-ALK Fusion in NSCLC Clinical Diagnosis and Dynamic Monitoring

Untreated Advanced NSCLC Patients | FISH Identified ALK Fusion Positive or Negative

China
British Columbia Cancer Agency
Insight Genetics

Completed

Comparison of qPCR to IHC and FISH for Detection of ALK Fusion Mutations in FFPE Tissue From NSCLC Patients (PCRTALK)

Nonsmall Cell Lung Cancer

Canada
ALK-Abelló A/S

Completed

A Trial of the ALK Grass Tablet in Subjects With Hayfever

Allergy

Denmark
ALK-Abelló A/S

Completed

Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets

Allergy

Spain
Harbin Medical University

Completed

Therapeutic Effect of Crizotinib for Rearrangement-negative, High Phosphorylated ALK Patients

ALK Phosphorylation

China
UMC Utrecht
Dr. F.P. Fischer-stichting, Utrecht, The Netherlands

Terminated

PENTACON Trial: Partial ENdothelial Trepanation in Addition to Anterior Lamellar Keratoplasty in keratoCONus (PENTACON)

Keratoconus

Netherlands
Betta Pharmaceuticals Co., Ltd.

Unknown

The Absorption, Metabolism and Excretion of [14C]Ensartinib in Human

ALK-POSITIVE NSCLC

China
ALK-Abelló A/S

Completed

Efficacy and Safety Trial of the ALK HDM Tablet in House Dust Mite Allergic Subjects

Asthma

Denmark
Lars Olaf Cardell

Completed

Follow up Study 5-6 Years After ILIT With 2 Concomitant Allergens, Birch and Grass

Allergic Rhinitis

Sweden
Xcovery Holding Company, LLC

Available

Expanded Access to Ensartinib for Participants With ALK+ NSCLC

Non-Small Cell Lung Cancer | ALK Gene Rearrangement Positive

United States
Novartis Pharmaceuticals

Recruiting

Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study

ALK Positive Malignancies

Germany, France, Australia, Belgium, Italy, Korea, Republic of, Poland, China, United States, Taiwan, Brazil, Bulgaria, Hong Kong, Japan, Lebanon, Malaysia, Spain, Russian Federation, Colombia, Singapore, Czechia
The Lymphoma Academic Research Organisation
Pfizer; Takeda; Hôpital Necker-Enfants Malades; Fondation ARC

Completed

Prospective Study of the Prognostic Value of New Markers in Adults With ALK-positive Large Anaplastic Lymphoma

Anaplastic Large Cell Lymphoma, ALK-Positive

France
Alkermes, Inc.

Completed

Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
National Jewish Health
ALK-Abelló A/S

Completed

Dog Hair Extract Study

Potency of Dog Hair Extract

United States
Ludwig Institute for Cancer Research
Xcovery Holding Company, LLC; Cancer Research Institute, New York City; MedImmune...

Completed

Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer

Carcinoma | NSCLC | Non-small Cell Lung Cancer

United States
ALK-Abelló A/S

Completed

Safety of ALK Ragweed Tablet

Allergy

United States
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital

Completed

Intralymphatic Immunotherapy in Increasing Doses, Substudy

Rhinitis, Allergic, Seasonal

Sweden
Alkermes, Inc.

Terminated

Phase 1 ALKS 1140 in Healthy Adults

Central Nervous System Diseases

Australia
Pfizer

Completed

An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Carcinoma, Non-Small-Cell Lung

United States, Canada, Spain, China, Brazil, United Kingdom, Japan, Poland, Australia, France, Ireland, Taiwan, Italy, Germany, Netherlands, Korea, Republic of, Bulgaria, Greece, Hong Kong, Hungary, Russian Federation, Sweden
Pfizer

Recruiting

Lorlatinib Continuation Study

NSCLC | Non-Small-Cell Lung Cancer

Spain, Taiwan, France, China, Singapore, Japan, United States
Abbott
Datamap; Linical Co., Ltd.

Completed

A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma

Asthma | Allergy | Rhinitis

Belarus, Russian Federation
Li Zhang, MD

Recruiting

Ensatinib Treat Second-generation ALK-TKI Resistance After Second-generation ALK-TKI Resistance (ERSGATR)

The Diagnosis Was ALK Positive NSCLC | Second Generation ALK-TKI is Resistant | Efficacy of Ensatinib in This Subset of Patients

China
Hoffmann-La Roche

No longer available

Expanded Access to Entrectinib for Cancers With NTRK1/2/3, ROS1, or ALK Gene Fusions

Cancers With NTRK, ROS1, or ALK Gene Fusions

United States
Hunan Province Tumor Hospital

Completed

ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Pure Squamous Cell Carcinoma

Non-small Cell Lung Cancer

China
Hoffmann-La Roche

Terminated

A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors (ALpha-T)

Digestive System Diseases | Gastrointestinal Diseases | Melanoma | Sarcoma | Neoplasms | Respiratory Tract Diseases | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasms | Head and Neck Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms and other conditions

United States
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of LEE011 and Ceritinib in Patients With ALK-positive Non-small Cell Lung Cancer.

Non-small Cell Lung Cancer

Taiwan, Spain, Italy, United States, Korea, Republic of, France
Novartis Pharmaceuticals

Completed

LDK378 in Adult Chinese Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Non-Small Cell Lung Cancer

China
Pfizer

Completed

Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)

Non-Small Cell Lung Cancer

Spain
Centre Hospitalier Universitaire de Nice

Completed

Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients (STALKLUNG01)

Lung Neoplasms

France
Memorial Sloan Kettering Cancer Center
Xcovery Holding Company, LLC

Active, not recruiting

Treating Patients With Melanoma and ALK Alterations With Ensartinib

Melanoma

United States
Pfizer

Completed

An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Carcinoma, Non-Small-Cell Lung

United States, Canada, Spain, China, United Kingdom, Poland, France, Ireland, Japan, Taiwan, Germany, Netherlands, Italy, Brazil, Russian Federation, Korea, Republic of, Australia, Bulgaria, Greece, Hong Kong, Hungary, Sweden
University of Milano Bicocca
Pfizer

Recruiting

A Study of Oral Lorlatinib in Patients With Relapsed ALK Positive Lymphoma (CRU3)

Anaplastic Large Cell Lymphoma, ALK-Positive

Italy
ALK-Abelló A/S

Completed

Efficacy and Safety Trial of ALK-depot SQ Mites in Subjects With Atopic Dermatitis

Atopic Dermatitis

Germany
European Organisation for Research and Treatment...

Active, not recruiting

Activity of Lorlatinib Based on ALK Resistance Mutations Detected on Blood in ALK Positive NSCLC Patients (ALKALINE)

Non Small Cell Lung Cancer

Netherlands, Spain, France, United Kingdom, Norway, Jordan, Belgium
Aarhus University Hospital
University of Aarhus; University Hospital, Linkoeping

Active, not recruiting

Documentation of Efficacy of Intralymphatic Allergen Immunotherapy (ILITNU)

Allergic Rhinitis Due to Grass Pollen | Allergic Asthma | Allergic Conjunctivitis of Both Eyes

Denmark, Sweden

Search clinical trials for: anaplastic lymphoma kinase (ALK)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Morocco

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations