Search clinical trials for: apoB

Total 39 results

Pauls Stradins Clinical University Hospital

Recruiting

Latvian Early Atherosclerosis Registry

Coronary Artery Disease | Atherosclerosis, Coronary

Latvia
Lawson Health Research Institute
Apobiologix.

Not yet recruiting

Lapelga vs Gastrofil

Lymphoma | Multiple Myeloma | Febrile Neutropenia | Engagement, Patient
Marcello Arca
Pfizer; Göteborg University; University of Helsinki

Not yet recruiting

In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects

Familial Hypobetalipoproteinemia | Familial Hypobetalipoproteinemia - Heterozygous Form
University of British Columbia
Vancouver Coastal Health Research Institute; Genome British Columbia

Recruiting

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

Acute Coronary Syndrome | Familial Hypercholesterolemia | STEMI | NSTEMI - Non-ST Segment Elevation MI | Familial Hypercholesterolemia - Heterozygous | Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation and other conditions

Canada
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

Atherogenic Lipoproteins in Ischemic Stroke (AGELESS)

Ischemic Stroke

Switzerland
Institut de Recherches Cliniques de Montreal
Canadian Institutes of Health Research (CIHR)

Recruiting

Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Inflammation | Type 2 Diabetes | Insulin Sensitivity/Resistance | Fatty Acids, Omega-3

Canada
University of Malaya
National University Hospital, Singapore; Merck Sharp & Dohme LLC; Cancer Research...

Recruiting

Study of Pembrolizumab in Metastatic HER2-negative Breast Cancer Patients With APOBEC3B Mutation

HER2-Negative Breast Cancer

Singapore, Malaysia
Manchester University NHS Foundation Trust

Recruiting

Abnormal Lipids - Causes and Effects

Hypertriglyceridaemia

United Kingdom
Organon and Co

Completed

A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)

Dyslipidemia | Hypercholesterolemia

Korea, Republic of
The Hospital of Vestfold
Oslo University Hospital

Active, not recruiting

Prevention of Coronary Heart Disease in Morbidly Obese Patients (SphCor)

Hypertension | Obstructive Sleep Apnea | Morbid Obesity | Osteoarthrosis | Type 2 DM

Norway
May Faraj, PDt, PhD
Canadian Institutes of Health Research (CIHR)

Completed

Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood

Type 2 Diabetes | Inflammatory Response | Insulin Sensitivity/Resistance | Fatty Acids, Omega-3
Karolinska University Hospital

Completed

ApoB48 Metabolism in Plasma and Interstitial Fluid

Diabetes Mellitus, Type 2

Sweden
Medical University Innsbruck

Unknown

Characterization of Two Novel Mutations in the Apob Gene

Familial Hypobetalipoproteinaemia - Heterozygous Form | Low-LDL-syndrome

Austria
Lisa Tannock
VA Office of Research and Development

Completed

The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk

Cardiovascular Disease

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Lipid Metabolism, Inborn Errors | Hypobetalipoproteinemias | Hypolipoproteinemias | Hypolipopro... and other conditions

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Determine the Effects of Multiple Doses of Mipomersen (200 mg SC) on the Pharmacodynamics and Pharmacokinetics of Single-dose Warfarin

Healthy

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Healthy Volunteers

Healthy Volunteer

Canada
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Mipomersen on Cardiac Repolarization Conducted in Healthy Subjects

Healthy

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study in Subjects on Stable Statin Therapy

Hypercholesterolemia

Netherlands, United States
Osaka University
Merck Sharp & Dohme LLC

Unknown

Relationship Between CETP Deficiency and Atherosclerosis in Patients With Hyperalphalipoproteinemia (INFINITY)

Hyper-LDL-cholesterolemia | Low CETP Activity | CETP Deficiency | Hyperalphalipoproteinemia | High Level of Remnant Cholesterol

Japan
University Health Network, Toronto

Completed

Regulation of Intestinal and Hepatic Lipoprotein Production by Glucose and Fructose (glucose)

Hyperlipidemia

Canada
University Health Network, Toronto

Completed

Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2

Dyslipidemia

Canada
Oslo University Hospital

Completed

Topical Treatment With Fresh Human Milk Versus Emollient on Atopic Eczema Spots in Young Children

Atopic Eczema
Scripps Clinic

Unknown

Comparison of LDL Particle Count With Other Available Lipid Tests (LIPID)

Hyperlipidemia

United States
Assistance Publique Hopitaux De Marseille

Completed

Acute Effect of Intensive Insulin Infusion on Intestinal Triglyceride-rich-lipoprotein-apoB48 Metabolism in Type 2 Diabetic Patients

Type 2 Diabetes

France
Essentialis, Inc.
Medpace, Inc.

Completed

Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia

Dyslipidemia | Hypertriglyceridemia
Federal University of São Paulo

Completed

Weekly Zinc Chelate Supplementation on Children's Growth (APZinc)

Short Stature
University Health Network, Toronto
Eli Lilly and Company

Completed

Exenatide (Byetta ®) Regulation of Intestinal and Hepatic Lipoprotein Particle Production in Humans

Hyperlipidemia

Canada
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of SPC4955 in Healthy Subjects

Hypercholesterolemia

Germany
University of Pennsylvania
Johnson & Johnson

Completed

Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina

Vulvovaginal Candidiasis | Health

United States
Seoul National University Hospital
Merck Sharp & Dohme LLC

Unknown

Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes

Type 2 Diabetes Mellitus Without Insulin Treatment

Korea, Republic of
Arbutus Biopharma Corporation

Terminated

Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Liposomal siRNA in Subjects With High Cholesterol

Hypercholesterolemia

United States
University Hospital, Bonn

Completed

Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion (SVS)

Hypercholesterolemia

Germany
Centre Hospitalier Universitaire Dijon
AstraZeneca

Completed

Effects of Rosuvastatin on the, in Vivo, Kinetic of apoB and apoA1, Using Stable Isotopes, in Type 2 Diabetic Patients

Diabetes

France
AstraZeneca

Completed

Effects in The ApoB/ApoA-I Ratio Using Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

France, Italy, Spain, Estonia, Hungary, Canada, Belgium, Portugal, Greece, Ireland, Tunisia

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