Search clinical trials for: apoB-100

Total 3721 results

Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study in Subjects on Stable Statin Therapy

Hypercholesterolemia

Netherlands, United States
Osaka University
Merck Sharp & Dohme LLC

Unknown

Relationship Between CETP Deficiency and Atherosclerosis in Patients With Hyperalphalipoproteinemia (INFINITY)

Hyper-LDL-cholesterolemia | Low CETP Activity | CETP Deficiency | Hyperalphalipoproteinemia | High Level of Remnant Cholesterol

Japan
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Lipid Metabolism, Inborn Errors | Hypobetalipoproteinemias | Hypolipoproteinemias | Hypolipopro... and other conditions

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
University Hospital, Bonn

Completed

Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion (SVS)

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Astellas Pharma Inc
Toray Industries, Inc

Completed

Study to Compare Pharmacokinetic Profiles of TRK-100STP in Japanese, Chinese, and South Korean Non-elderly Healthy Adult Males

Healthy Adult Male | Pharmacokinetics of TRK-100-STP

Japan
Lisa Tannock
VA Office of Research and Development

Completed

The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk

Cardiovascular Disease

United States
Göteborg University
Sahlgrenska University Hospital, Sweden

Completed

Effect of Body Weight Loading on Urinary Electrolyte Excretion (EBU)

Obesity | Edema

Sweden
Medinox, Inc.
Orient Europharma Co., Ltd.

Completed

NOX-100 for Preventing Hypotension During Hemodialysis

Hypotension

Taiwan
Istinye University

Completed

Pectoralis Minor Shorthening and Swimming Performance

The Study Will Not be Based on Any Disease | Ability to Swim 100m Independent Freestyle | Be Between the Ages of 9-16 | Continuing Running as Part of a Sports Club

Turkey
National Taiwan University Hospital

Recruiting

Ropeginterferon Alfa 2b for Early MyelofibrosisDIPSS Low/Intermediate-1 Risk Myelofibrosis

Pre-fibrotic Myelofibrosis

Taiwan
National Taiwan University Hospital

Recruiting

Clinical Decision-Making and Virtual Reality Exercise

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Intervertebral Discs | Degenerative Lumbar Spinal Stenosis

Taiwan
Heron Therapeutics

Active, not recruiting

Safety Study of Repeat Doses of SUSTOL in Adults

Chemotherapy-Induced Nausea and Vomiting (CINV)

United States
Bharat Biotech International Limited

Completed

A Trial Using Double-Bolus THR-100 Versus Streptokinase (THR-100)

Acute Myocardial Infarction

India
University Health Network, Toronto

Completed

Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2

Dyslipidemia

Canada
National Taiwan University Hospital

Active, not recruiting

Analysis of Risk Factors and Prognosis of Pediatric Patients After Operations for Congenital Heart Disease

Congenital Heart Disease | Pediatric

Taiwan
Azienda Ospedaliero-Universitaria Consorziale Policlinico...
Prof. Carlo Manno; Dott. Francesco Pesce; Dott. Michele Rossini; Dott. Vincenzo...

Unknown

Correlation Between Platelet Function Analyzer-100 Testing and Bleeding Events After Percutaneous Kidney Biopsy

Kidney Diseases | Hemorrhage | Blood Platelet Disorder

Italy
Medical University Innsbruck

Unknown

Characterization of Two Novel Mutations in the Apob Gene

Familial Hypobetalipoproteinaemia - Heterozygous Form | Low-LDL-syndrome

Austria
Pusan National University Hospital
Pusan National University Yangsan Hospital

Unknown

Nasogastric Tube Insertion Using Cook Airway Exchange Catheter in Anesthetized Patients

Elective Surgery of Gastrointestinal Tract | 100 Adults Aged Between 20 and 70 Years Old | ASA Physical Status of I or II

Korea, Republic of
Thai Red Cross AIDS Research Centre
Johns Hopkins University; Centers for Disease Control and Prevention; The HIV...

Completed

Behavioral and Biomedical HIV Prevention Interventions for Thai Men Who Have Sex With Men (HIV-NAT 120)

HIV Testing, MSM

Thailand
Novartis
Novartis Vaccines

Completed

A Study to Evaluate Safety and Immunogenicity of Trivalent Influenza Vaccine, Formulation 2015 Southern Hemisphere, When Administered to Healthy Adult Subjects.

Human Influenza

Brazil
Essentialis, Inc.
Medpace, Inc.

Completed

Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia

Dyslipidemia | Hypertriglyceridemia
University of Malaya
Pfizer; Cancer Research Malaysia; Pantai Hospital Kuala Lumpur; Hospital Sultan...

Recruiting

Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature

Triple Negative Breast Cancer | HRD 100 Gene Expression High

Malaysia
University of Mississippi Medical Center

Terminated

Does An Abnormal PFA 100 Predict Bleeding After Renal Biopsy?

Hemorrhage | Kidney Failure, Chronic | Blood Platelet Disorders | Kidney Failure, Acute

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Marcello Arca
Pfizer; Göteborg University; University of Helsinki

Not yet recruiting

In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects

Familial Hypobetalipoproteinemia | Familial Hypobetalipoproteinemia - Heterozygous Form
Arbutus Biopharma Corporation

Terminated

Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Liposomal siRNA in Subjects With High Cholesterol

Hypercholesterolemia

United States
La Jolla Pharmaceutical Company

Completed

Study of the Safety of GCS-100 in Subjects With Chronic Lymphocytic Leukemia (PR-CS008)

Chronic Lymphocytic Leukemia

United States
Ranbaxy Laboratories Limited

Completed

A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal

Healthy
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees

Knee Osteoarthritis

United States
University of Florida
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Effects of Deep Brain Stimulation on Motor, Mood, and Cognitive Symptoms in Parkinson's Disease

Parkinson Disease

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Hepatic Encephalopathy | Urea Cycle Disorders

Ukraine
Mespere Lifesciences Inc.

Unknown

ED Decision Making Among Hypotensive Patients

Hypotension

United States
University of California, Los Angeles

Completed

NOrth American Study for the Treatment of Recurrent epIstaxis With DoxycycLine: The NOSTRIL Trial (NOSTRIL)

Epistaxis

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Wageningen University
Friesland Campina

Unknown

Postprandial Effects of Milk Fats (POEMI)

Nutrition | Metabolism | Genomics | Postprandial Metabolism

Netherlands
Aalborg University Hospital
Aarhus University Hospital

Completed

Assessment of Serum Cystatin C as a Marker of Kidney Function in Children

Kidney Disease

Denmark
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Evaluate the Effectiveness of First Aid E-book Intervention Among New Nurses

First Aid | Knowledge | Self-efficacy

Taiwan
San Diego State University

Completed

AVACEN Treatment Method and Postprandial Blood Glucose

Postprandial Hyperglycemia

United States
Medical University of Vienna

Recruiting

The Effect of Hyperoxia and Hypoxia on Fluorescence Lifetime Imaging Ophthalmoscopy in Healthy Subjects- a Randomized, Double Blind, Crossover Study

To Investigate the Effect of 100% Oxygen Breathing on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Healthy Subjects

Austria
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Determine the Effects of Multiple Doses of Mipomersen (200 mg SC) on the Pharmacodynamics and Pharmacokinetics of Single-dose Warfarin

Healthy

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Healthy Volunteers

Healthy Volunteer

Canada
Revogenex, Inc.

Suspended

A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)

Irritable Bowel Syndrome

United States
PellePharm, Inc.

Completed

Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas (BCC)

Basal Cell Carcinomas

United States
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of SPC4955 in Healthy Subjects

Hypercholesterolemia

Germany
Sumitomo Pharma America, Inc.
BehaVR LLC

Completed

A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder. (BVR-100-102)

Social Anxiety Disorder (SAD)

United States
Karolinska Institutet
Thrasher Research Fund

Completed

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia Study (Neo-HAT)

Thrombocytopenia

Sweden, United States
ExThera Medical Corporation

Completed

Safety Evaluation of Seraph® 100 to Reduce Bacteremia in Patients on Hemodialysis

Bacteremia | Bacterial Infection

Germany

Search clinical trials for: apoB-100

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