Search clinical trials for: artemisin

Total 134 results

Infectious Diseases Research Collaboration, Uganda
London School of Hygiene and Tropical Medicine; Radboud University Medical...

Recruiting

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy (SPARTAN)

Falciparum; Malaria

Uganda
Frantz Viral Therapeutics, LLC
Anal Dysplasia Clinic MidWest; Laser Surgery Care, LLC

Recruiting

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants (ART-AIN IIB-2)

Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL | Anal HPV Infection

United States
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
University of Oxford

Not yet recruiting

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines (FD-TACT)

Uncomplicated Plasmodium Falciparum Malaria
Shoklo Malaria Research Unit
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

ACT vs CQ With Tafenoquine for P. Vivax Mono-infection (ACTQ)

Malaria | Malaria, Vivax | Plasmodium Vivax Malaria

Thailand
Muhimbili University of Health and Allied Sciences
Uppsala University; The Swedish Research Council

Not yet recruiting

Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial (3ACT)

Uncomplicated Plasmodium Falciparum Malaria

Tanzania
Makerere University

Recruiting

Ivermectin-artemisinin Combination Therapy for Eradication of Malaria (IVIME)

Malaria

Uganda
Oncotelic Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of OT-101+Artemisinin in Hospitalized COVID-19 Subjects

COVID-19

Brazil
Shanghai Tong Ren Hospital

Recruiting

Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction (PERFECT-AMI)

Early PCSK9 Inhibitor on Ventricular Remodling

China
Frantz Viral Therapeutics, LLC
M.D. Anderson Cancer Center; University of Michigan; The Cleveland Clinic; Amarex... and other collaborators

Recruiting

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) (ART-CIN_IIB)

HPV Infection | CIN 2/3 | Cervical Dysplasia | Pre-Cancerous Dysplasia | HPV Related Disease

United States
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. (DeTACT-Africa)

Plasmodium Falciparum Malaria (Uncomplicated)

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Guinea, Nigeria, Niger, Rwanda, Tanzania
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Alder Hey Children's...

Recruiting

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) (AIR:RRP)

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United Kingdom
St George's, University of London

Recruiting

A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer (NeoART)

Colorectal Cancer | Bowel Cancer

United Kingdom
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
Centers for Disease Control and Prevention
Ministry of Health, Liberia

Completed

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia

Malaria | Plasmodium Falciparum | Uncomplicated Malaria

Liberia
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Clinton Health... and other collaborators

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria

Malaria | Febrile Illness

Nigeria
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Clinton Health... and other collaborators

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya

Malaria | Febrile Illness

Kenya
Ministry of Public Health, Democratic Republic...
Centers for Disease Control and Prevention; Global Fund

Active, not recruiting

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo (TES2022)

Uncomplicated Plasmodium Falciparum Malaria

Congo, The Democratic Republic of the
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Centro de Investigação em Saúde de Manhiça
United States Agency for International Development (USAID)

Active, not recruiting

In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique (MEFI_IV)

Malaria

Mozambique
Beni-Suef University
University of Arizona; Maternity and Children Hospital, Makkah

Completed

Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With (COVID-19)

Covid19 | Immunodeficiency

Saudi Arabia
University of Oxford

Completed

Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam (TACT-CV)

Malaria, Falciparum

Cambodia, Vietnam
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Copenhagen; University... and other collaborators

Completed

Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa (IMPROVE)

Pregnancy | Malaria | Malaria in Pregnancy

Kenya, Malawi, Tanzania
Epicentre
University of Cape Town; Medecins Sans Frontieres, Netherlands; Shoklo Malaria...

Completed

Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy

Malaria

Uganda
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
Princess Nourah Bint Abdulrahman University

Withdrawn

Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19

Corona Virus Infection | Covid 19 Positive

Saudi Arabia
University of Oxford

Completed

Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy (DMA)

Malaria

Thailand
Groupe de Recherche Action en Sante
Medicines for Malaria Venture; National Malaria Control Programme (NMCP), Burkina... and other collaborators

Completed

Feasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies

Malaria

Burkina Faso
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

P.Vivax Treatment Trial (Lao Pv)

Plasmodium Vivax

Lao People's Democratic Republic
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Terminated

Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria

Malaria

Korea, Republic of
Johns Hopkins University
University of Wisconsin, Madison; Frantz Viral Therapeutics, LLC

Completed

Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3) (ART-AIN)

Precancerous Conditions | Human Papilloma Virus | Anal Dysplasia | HPV-Related Anal Intraepithelial Neoplasia | AIN2/3 | Artesunate | Alternative Treatment

United States
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients

Malaria

Congo, The Democratic Republic of the, Gambia, Ghana, Indonesia, Kenya, Mali, Mozambique, Philippines, Senegal
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria

Malaria

Indonesia, Cambodia, India, Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria

Plasmodium Falciparum Malaria

Cambodia, Gambia, Indonesia, Senegal, Thailand, Uganda
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Worcester Polytechnic Institute
Plesion International, Coatesville, PA; HEAL Africa Hospital, Goma, Democratic... and other collaborators

Withdrawn

Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria

Malaria

Congo, The Democratic Republic of the
Mateon Therapeutics
Windlas Biotech Private Limited

Completed

A Study to Evaluate the Safety and Efficacy of Artemisinin- a Herbal Supplement on COVID-19 Subjects

Covid19

India
London School of Hygiene and Tropical Medicine
University of Yaounde; Cameroon Baptist Convention Health

Completed

Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon

Malaria
Centre national de recherche et de formation sur...
Programme national de lutte contre le paludisme (PNLP), Burkina Faso; Unité... and other collaborators

Unknown

Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) (CHIMIO2)

Malaria | Burkina Faso

Burkina Faso
University of Molise

Active, not recruiting

Effects of a Therapy With INTRAVIT® Tablets in Patients With Diabetic Retinopathy

Diabetic Retinopathy

Italy
Swiss Tropical & Public Health Institute
Makerere University; Kinshasa School of Public Health; Clinton Health Access... and other collaborators

Completed

Monitoring of Molecular Markers of Artemisinin Resistance Through Repeated Cross-sectional Assessments in DR Congo, Nigeria and Uganda (Caramal DRM)

Severe Malaria

Congo, The Democratic Republic of the, Nigeria, Uganda
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Moi University; Clinton Health Access Initiative, Nigeria

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 (TESTsmART)

Malaria | Febrile Illness

Kenya
Grant Dorsey, M.D, Ph.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants (PROMOTE-BC1)

Malaria

Uganda
University of Oxford
World Health Organization

Completed

SPK Study in Afghanistan

Uncomplicated P. Falciparum Malaria

Afghanistan
University of Oxford
FHI 360; Oxford University Clinical Research Unit, Vietnam; Shoklo Malaria Research... and other collaborators

Completed

Targeted Chemo-elimination (TCE) of Malaria (TME)

Plasmodium Falciparum Malaria

Thailand, Cambodia, Lao People's Democratic Republic, Myanmar, Vietnam
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Indonesia
Liverpool School of Tropical Medicine
The Research Council of Norway; Makerere University; Kenya Medical Research Institute

Completed

Post-discharge Malaria Chemoprevention(PMC) Study (PMC)

Malaria | Severe Anemia

Uganda, Kenya
Centro de Investigação em Saúde de Manhiça
United States Agency for International Development (USAID)

Completed

In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) (MEFI_III)

Malaria

Mozambique
Neopharma Japan Co., Ltd.
Parexel

Withdrawn

A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria

Malaria

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