Search clinical trials for: baclofen, withdrawal, interuption, spasticity, pharmacokinetics, tolerability, intravenous, oral

Total 17381 results

GlaxoSmithKline

Completed

Study To Examine Safety, Tolerability And Pharmacokinetics Of Intravenous Doses And Oral Dose Of GSK233705

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate Safety, Blood Levels And Effects Of Giving GW642444, By Mouth, By Inhalation & By Injection

Pulmonary Disease, Chronic Obstructive

United Kingdom
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Chronic Hepatitis B

Belgium, Germany, United Kingdom, Philippines
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Study to Assess the Pharmacokinetics of of ASA404 in Adult Cancer Patients With Impaired Hepatic Function

Histologically-proven and Radiologically-confirmed Solid Tumors

Italy, New Zealand
GlaxoSmithKline

Completed

To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809

Substance Dependence

Germany
GlaxoSmithKline

Terminated

A Study To Evaluate The Effect Of GW876008 On The Pharmacokinetics Of Oral Contraceptive Pills

Social Phobia

United Kingdom
GlaxoSmithKline

Completed

The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects

Nausea and Vomiting, Chemotherapy-Induced

United States
GlaxoSmithKline

Completed

Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine Reward

Substance Dependence

United States
GlaxoSmithKline

Completed

A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In COPD Patients.

Pulmonary Disease, Chronic Obstructive

Germany
AstraZeneca

Completed

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Solid Tumours

Belgium, Denmark, United Kingdom, Netherlands
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594

Pharmacokinetics | Safety | Pharmacodynamics of AZD7594

United Kingdom
GlaxoSmithKline

Completed

A Study of the Effects of GSK189075 on PK Profiles of an Oral Contraceptive Pill When Given to Healthy Female Volunteers

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

A Three-Part Study Of GSK580416 In Healthy Subjects

Infections, Bacterial | Respiratory Tract Infection

Australia
AbbVie

Not yet recruiting

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia
Tufts University

Not yet recruiting

Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planus

Oral Lichen Planus | Oral Lichenoid Reaction

United States
Region Skane
The George Institute for Global Health, Australia

Not yet recruiting

International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER)

Stroke | Intraventricular Hemorrhage | Cerebrovascular Disease | Intracerebral Hemorrhage | Intracerebral Haemorrhage

Australia, Sweden
International Research Training Group 2804
German Research Foundation; Uppsala University; University Hospital Tuebingen

Not yet recruiting

Social Media Usage in Adolescent Girls

Menstrual Cycle | Oral Contraceptive

Germany
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Calico Life Sciences LLC
AbbVie

Not yet recruiting

Study of [14C] ABBV-CLS-7262 in Healthy Male Volunteers Following Single Oral Dose Administration

Healthy Volunteer

United States
Centre Leon Berard

Not yet recruiting

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO) (TACO)

Oral Squamous Cell Carcinomas

France
Xintian Pharmaceutical

Not yet recruiting

Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules (ESPTTN)

Thyroid Nodule

China
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Istituto Clinico Humanitas

Not yet recruiting

Efficacy and Safety of Oral Administration of Postibiotic by FOS Fermentation From Lactobacillus Paracasei in the Treatment of Irritable Bowel Syndrome. (prePO23)

IBS - Irritable Bowel Syndrome

Italy
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Not yet recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Bacteremia | Endocarditis

Spain
British University In Egypt

Not yet recruiting

Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers

Treatment Compliance | Aphthous Stomatitis (Major) (Minor)

Egypt
Cairo University

Not yet recruiting

Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar

Irreversible Pulpitis

Egypt
The First Affiliated Hospital of Henan University...

Not yet recruiting

Clinical Study on the Effect of Removal of Porphyromonas Gingivalis on Prognosis of Esophageal Cancer After Radical Surgery

Evaluate the DFS of Patients With Esophageal Cancer Who Underwent Radical Operation After Regular Removal of Porphyromonas Gingivalis
University of Southern California

Not yet recruiting

Ketamine HCl Prolonged Release Oral Tablets for CRPS

Complex Regional Pain Syndromes

United States
University of Udine

Recruiting

Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy (ENDOmiRNA)

Endometriosis

Italy
AbbVie

Not yet recruiting

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Migraine
Incyte Corporation

Recruiting

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics When Administered Orally to Healthy Adult Participants

Healthy Participants

United States
Women's Hospital School Of Medicine Zhejiang University

Recruiting

Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women

Endometrial Hyperplasia | Endometrial Cancer Stage I

China
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
AbbVie

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABBV-1088 Oral Dose in Healthy Adult Participants.

Healthy Volunteers

United States
University Center of Dental Medicine Switzerland
University of Wuerzburg; Helmholtz Centre for Infection Research

Recruiting

Effect of Dietary Supplements on the Oral Microbiome

Nutrition, Healthy

Germany, Switzerland
Children's University Hospital Cologne, Germany
University of Cologne; University of Geneva, Switzerland; The Clinical Trials...

Not yet recruiting

Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders (ZINCGNAO1)

Epilepsy | Dystonia | Development Delay | GNAO1 | Developmental and Epileptic Encephalopathy 17 | Neurodevelopmental Disorder With Involuntary Movements | Choreoathetosis
Celgene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Healthy Participants

United States
Ain Shams University
Dar EL Salam Cancer Hospital

Recruiting

Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients

Breast Cancer | Chemotherapy | Neurologic Disorder | Paclitaxel | Alpha Lipoic Acid

Egypt
University of Aarhus

Not yet recruiting

Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment

Quality of Life | Dysphagia | Oral Cavity Cancer

Denmark
University of Giessen

Recruiting

Topical Application of PRF Before Radiation Therapy (PRF)

PRF

Germany
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer (POMPPR)

Pain, Postoperative | Anxiety | Sleep Disturbance | Preoperative | Midazolam

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia

Mastalgia

China
Ottawa Heart Institute Research Corporation

Not yet recruiting

Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension (MIDOH-HF-P)

Hypotension | Heart Failure With Reduced Ejection Fraction | LV Dysfunction
Umraniye Education and Research Hospital

Recruiting

Effects of Malnutrition on Respiratory and Renal Functions in Patients Undergoing Peroral Endoscopic Myotomy (POEM)

Achalasia

Turkey
Medipol University

Not yet recruiting

The Effect of Oral Use of Lyophilised Royal Jelly on Cognitive Functions and Immune System in Elderly Individuals

Cognitive Change
HoHo Biotech
Tri-Service General Hospital; Taoyuan Armed Forces General Hospital

Recruiting

To Evaluate the Efficacy of Oral Molecular Hydrogen Supplement in Patients With Chronic Diseases

Chronic Disease | Chronic Inflammation

Taiwan
Hospital Sirio-Libanes
Daiichi Sankyo

Not yet recruiting

Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE) (VISIONAIRE)

Chronic Kidney Diseases | Atrium; Fibrillation
Azienda Ospedaliero-Universitaria Careggi

Not yet recruiting

Comparison of Customized and Standard Facemasks for Early Treatment of Class III Malocclusion

Malocclusion, Angle Class III | Extraoral Traction Appliances

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