Search clinical trials for: biologic

Total 6829 results

Hospices Civils de Lyon

Not yet recruiting

Circadian Rhythmicity During Coma Awakening (COMARHYTHM)

Acute Brain Injury Coma
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Biological Collection of Neurocognitive Disorders (BioCogBank)

Neurocognitive Disorders
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

United States, Chile, Canada, United Kingdom
Northwestern University
National Cancer Institute (NCI)

Not yet recruiting

Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

B-Cell Non-Hodgkin Lymphoma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Intestinal Akkermansia Muciniphila in Prostate Cancer (AkkPRO)

Metastatic Castration-resistant Prostate Cancer
Academic and Community Cancer Research United

Not yet recruiting

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

Primary Mediastinal Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Gastric or Gastroesophageal Junction Adenocarcinoma (G-HOPE-001)

Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

China
Stichting European Myeloma Network
Janssen, LP

Recruiting

European Myeloma Network (EMN) Sample Project (EMN36)

Multiple Myeloma | Smoldering Multiple Myeloma | Plasma Cell Leukemia | MGUS | Extramedullary Myeloma

Italy, Austria, Czechia, Greece, Serbia
Fred Hutchinson Cancer Center
PromiCell Therapeutics, Inc.

Not yet recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Turnstone Biologics, Corp.

Recruiting

TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC

Squamous Cell Carcinoma of Head and Neck | Metastatic Squamous Cell Carcinoma

United States
KU Leuven

Not yet recruiting

Iron and Zinc Absorption in Flakes Derived From Sprouted or Hydrothermally Processed Wheat (Wheatflakes)

Iron Absorption | Zinc Absorption
Imagine Institute

Recruiting

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions (IFN)

Autoimmune Diseases | Genetic Diseases | Neurological Disease | Immune Dysfunction

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Not yet recruiting

Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Recurrent Multiple Myeloma
University Hospital, Montpellier

Not yet recruiting

Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy (PREDIPOC)

Cardiac Surgery | Cardiopulmonary Bypass | Coagulopathy

France
Medical University Innsbruck
University of Innsbruck

Not yet recruiting

Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain Correlates

Major Depressive Disorder

Austria
University of Michigan Rogel Cancer Center

Recruiting

Gilteritinib for the Treatment of ALK NSCLC

Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8

United States
CanSino Biologics Inc.

Not yet recruiting

A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 18-59 Year Olds

Meningococcal Meningitis
Regina Elena Cancer Institute
University of Milan; Istituti Tumori Giovanni Paolo II

Recruiting

Analysis of HPV and Biomarkers Present in the Biological Fluids of Patients Suffering From Head and Neck Cancer as a Non-invasive Strategy for Detecting Recurrence

Head and Neck Tumors

Italy
National Cancer Institute (NCI)

Not yet recruiting

Studying TAK-243 in Patients With Advanced Cancer

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm
Laura Huppert, MD, BA
Ambrx, Inc.

Not yet recruiting

ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

Triple Negative Breast Cancer | Hormone Receptor Positive Breast Carcinoma | HER2 Low Breast Carcinoma | Hormone-receptor-positive Breast Cancer

United States
Tianjin ConjuStar Biologics Co., Ltd.

Recruiting

Study SC-101 in Subjects With Advanced Malignancies

Advanced Solid Tumor

China
Institut Claudius Regaud
NovoCure Ltd.

Not yet recruiting

Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed Glioblastoma (EXOFIELDS)

Glioblastoma

France
Uma Borate

Recruiting

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | Acute Myeloid Leukemia With KMT2A Rearrangement | Acute Myeloid Leukemia With NPM1 Mutation

United States
Thomas Jefferson University

Recruiting

Evaluation of a Mindfulness Intervention to Prevent Chemo-brain in Women Preparing for Chemotherapy for Breast Cancer

Breast Carcinoma

United States
Alaine E Hernandez, PhD
American Music Therapy Association

Recruiting

Music Therapy and Social Work Telehealth for Older Adult Well-Being (Melo-SWell)

Dementia | Telemedicine | Aging Well

United States
Novartis Pharmaceuticals

Not yet recruiting

Survey to Assess Physicians' Knowledge of Exjade Posology and Biological Monitoring Recommendations as Described in the Educational Materials

Chronic Iron Overload
University of California, San Francisco
Tobacco Related Disease Research Program; Alere San Diego

Not yet recruiting

CONNECTing to LungCare

Smoking Cessation | Lung Carcinoma | Cigarette Smoking-Related Carcinoma

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A First-in-human, Single-ascending-dose Study of IBI3002 in Healthy Participants and Mild to Moderate Asthmatics

Asthma | Healthy Participants

Australia
Universidad Católica San Antonio de Murcia

Not yet recruiting

Blood Bioavailability of Two Different Doses of a β-alanine Supplement (BIo-β) (Bio-β)

Bioavailability

Spain
University of Wisconsin, Madison
National Institute of Mental Health (NIMH)

Recruiting

Response to Acute Exercise in Eating Disorders

Eating Disorders

United States
National Cancer Institute (NCI)

Not yet recruiting

Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)

T Acute Lymphoblastic Leukemia | T Lymphoblastic Lymphoma
New Mexico Cancer Care Alliance
National Cancer Institute (NCI)

Recruiting

Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing (PE-CGS)

Malignant Neoplasm

United States
Nathan Denlinger
Bristol-Myers Squibb

Recruiting

CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma

B-Cell Non-Hodgkin Lymphoma-Recurrent | Diffuse Large B-Cell Lymphoma-Recurrent | Follicular Lymphoma-Recurrent | High Grade B-Cell Lymphoma-Recurrent | Primary Mediastinal Large B-Cell Lymphoma-Recurrent | Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma-Recurrent and other conditions

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study (ICE)

Exposure | Abuse Tobacco

United States
University of Illinois at Chicago
Lisa Tussing-Humphreys; Ardith Doorenbos; Beatriz Peñalver Bernabé; Mario Spaggiari and other collaborators

Recruiting

The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation (BIOME-KT)

Gut Microbiome | Kidney Transplant Symptoms

United States
Roswell Park Cancer Institute

Not yet recruiting

FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma and other conditions

United States
Mayo Clinic

Recruiting

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

Biochemically Recurrent Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8 | Oligometastatic Prostate Carcinoma | Recurrent Prostate Adenocarcinoma

United States
Rigshospitalet, Denmark

Recruiting

Intraoperative Biodegradable Stent Placement to Reduce Complications After Pancreatoduodenectomy

Fistula Pancreatic

Denmark
New York Stem Cell Foundation Research Institute

Recruiting

NYSCF Scientific Discovery Biobank

PTSD | Multiple Sclerosis | Cervical Cancer | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Macular Degeneration | Diabetes Mellitus, Type 1 | Parkinson Disease | Amyotrophic Lateral Sclerosis | Dementia | Ovarian Cancer | Alzheimer Disease | ALS | Vulvar Cancer | Post Traumatic Stress Disorder | Lewy Body Disease and other conditions

United States
New York Stem Cell Foundation Research Institute
Charcot-Marie-Tooth Association

Recruiting

Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for iPSC Generation and Biobanking

Healthy | Charcot-Marie-Tooth Disease

United States
National Cancer Institute (NCI)

Not yet recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, The PARAMMUNE Trial

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine (BioMetal)

Migraine | Migraine Headache | PFO - Patent Foramen Ovale | Migraine Headache, With or Without Aura

China
Instituto de Ciencia y Tecnología de Alimentos...
Ministry of Science and Innovation

Recruiting

Interindividual Variation in Response to Green Coffee (GREENCOF)

Overweight and Obesity

Spain
Elvira Umyarova
Sanofi

Recruiting

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Recurrent Multiple Myeloma

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Alesund Hospital

Not yet recruiting

Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women (PRERISK)

Preeclampsia

Norway
Roswell Park Cancer Institute

Not yet recruiting

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Tumors

Malignant Solid Neoplasm | Lung Neuroendocrine Neoplasm | Digestive System Neuroendocrine Neoplasm | Pancreatic Neuroendocrine Neoplasm

United States
Mayo Clinic

Not yet recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Zheng Liu

Recruiting

Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative Symptoms

Chronic Sinusitis

China
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Study of IBI3004 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Solid Tumor

Australia
Assistance Publique - Hôpitaux de Paris

Recruiting

Identification and Clinical Validation of Biomarkers Associated With Clinical Severity in Adults Infected With RSV (ARF-RSV)

Respiratory Syncytial Virus Infections

France

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