Search clinical trials for: bood brain barrier

Total 37034 results

Ji Xunming,MD,PhD

Recruiting

The Level of Blood Brain Barrier Damage Biomarker in Acute Ischemic Stroke

Ischemic Stroke

China
Cheng-Chia (Fred) Wu
Focused Ultrasound Foundation

Active, not recruiting

FUS Etoposide for DMG

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
yilong Wang

Recruiting

The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction (SOLUTION-2)

Stroke, Acute Ischemic | Blood-Brain Barrier

China
Chung-Ang University Gwangmyeong Hospital
National Research Foundation of Korea

Recruiting

The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients

Postoperative Cognitive Dysfunction

Korea, Republic of
Karamanoğlu Mehmetbey University

Recruiting

Physical Activity in Children With Wolff-Parkinson-White Syndrome

Wolff-Parkinson-White Syndrome

Turkey
Chang Gung Memorial Hospital

Not yet recruiting

Exploring Cerebrolysin in Late Thrombectomy for Stroke: Blood-brain Barrier Biomarkers and Imaging Insights

Acute Ischemic Stroke
The Third Affiliated hospital of Zhejiang Chinese...
Zhejiang University

Recruiting

Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma

Glioma

China
NaviFUS Corporation
NaviFUS US LLC

Not yet recruiting

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Neoplasms | Glioblastoma | Neoplasms, Nerve Tissue | Brain Tumor | Glioblastoma Multiforme

United States
University of California, Los Angeles

Not yet recruiting

Type 2 Diabetes and Blood Brain Barrier Improvement

Type2diabetes

United States
Hospital Universitario Dr. Jose E. Gonzalez
Ever Neuro Pharma GmbH

Recruiting

Effect of Cerebrolysin on the Blood Brain Barrier in Patients With Diabetes and Ischemic Stroke

Diabetes Mellitus, Type 2 | Ischemic Stroke, Acute | Blood Brain Barrier

Mexico
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Samsung Medical Center

Recruiting

Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly

Delirium, Postoperative

Korea, Republic of
Poznan University of Medical Sciences

Recruiting

CERebrolysine Effect on Blood-brain Barrier in acUte Ischemic Stroke (CERBERUS)

Acute Ischemic Stroke

Poland
University Hospital, Montpellier

Recruiting

Inflammation and Blood Brain Barrier Integrity as Biomarkers of Suicidal Behavior (IBBBiS)

Depression | Suicide

France
Kırıkkale University

Recruiting

Validity and Reliability of the Turkish Version of the Post-Stroke Physical Activity Barriers Scale in Patients With Stroke

Stroke | Physical Inactivity

Turkey
McGill University

Not yet recruiting

Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
Northwell Health

Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
Capital Medical University

Recruiting

Functional MRI to Assess Brain Damage in Cardiac Arrest Patients

Brain Injuries | Cardiac Arrest

China
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States
Centre Hospitalier Régional d'Orléans

Recruiting

Validation of the Apnea Test Performed by High-flow Oxygen Therapy in Patients With Clinical Brain Death (APNEAFLOW)

Brain Death

France
Hospices Civils de Lyon

Recruiting

Study of Changes in CSF Ionic Composition After Aneurysmal Meningeal Hemorrhage (ION_SAH)

Subarachnoid Hemorrhage

France
CarThera

Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM (SONOBIRD)

Glioblastoma | GBM | Recurrent Glioblastoma

France, United States, Spain, Belgium, Germany, Italy, Netherlands
Peking University First Hospital
Chinese Academy of Sciences

Recruiting

MRI Study of Blood-brain Barrier Function in CADASIL

Cadasil | Blood Brain Barrier Defect

China
New York Institute of Technology

Recruiting

Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients

Parkinson Disease | Osteopathy in Diseases Classified Elsewhere

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC; InSightec

Not yet recruiting

Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma

Recurrent Glioblastoma

United States
Northwestern University
Agenus Inc.; CarThera

Recruiting

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Glioblastoma Multiforme | Gliosarcoma | Newly Diagnosed Glioblastoma | Glioblastoma, Isocitric Dehydrogenase (IDH)-Wildtype

United States
University of Copenhagen

Recruiting

Changes in the Blood-brain Barrier During Maintenance ECT in Formerly Depressed Patients (3BECT)

Depression

Denmark
Lagos State University
Hydrocephalus Association

Recruiting

Barriers to Patients' Early Presentation, Diagnosis and Treatment in Childhood Hydrocephalus

Hydrocephalus in Children

Nigeria
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
McGill University
Canadian Institutes of Health Research (CIHR); McMaster University; Drexel University

Not yet recruiting

Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
University of Washington
Novo Nordisk A/S

Not yet recruiting

Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes

Diabetes Mellitus, Type 2 | Stroke (CVA) or Transient Ischemic Attack

United States
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (REPLENISH)

Polymyalgia Rheumatica

United States, Australia, Germany, Belgium, France, Spain, Italy, Lebanon, Switzerland, Japan, Israel, Denmark, Argentina, Netherlands, Colombia, Chile, Hungary, Poland, Turkey, Czechia, Brazil, South Africa, Mexico, Canada, United Kingdom
University of Cambridge
Radboud University Medical Center; Wolfson Brain Imaging Centre

Recruiting

INflammation and Small Vessel Disease Study (INSVD)

Stroke | Inflammation | Cerebral Small Vessel Diseases

Netherlands, United Kingdom
Mayo Clinic

Recruiting

Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption

Brain Tumor

United States
Johns Hopkins University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Imaging the Pathogenesis of Cerebral Small Vessel Disease

Hypertension | Diabetes | Ischemic Stroke | Hyperlipidemias

United States
InSightec

Recruiting

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

Brain Tumor

United States
InSightec

Recruiting

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

Brain Tumor

Canada
University of British Columbia

Not yet recruiting

Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease (ProD)

Depression | Parkinson Disease
InSightec

Recruiting

MR-guided Focused Ultrasound Plus GCase

Parkinsons Disease

Canada
Johns Hopkins University

Recruiting

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Ischemic Stroke

United States
Zhujiang Hospital

Recruiting

MAPT Haploid H1b and the Damage of BBB in Dorsal Medulla Oblongata and Autonomic Dysfunction in PD

Parkinson's Disease

China
Ali Rezai
InSightec

Recruiting

Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Standard of Care Monoclonal Antibody (mAb) Therapy

Mild Cognitive Impairment | Alzheimer Disease 1

United States
Capital Medical University

Recruiting

Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals

Venous Sinus Thrombosis, Cranial

China
InSightec

Recruiting

Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors

Glioma | Glioblastoma | Liquid Biopsy

United States, Canada
InSightec

Recruiting

Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

Brain Tumor

Korea, Republic of, United States, Canada
Ludwig-Maximilians - University of Munich

Recruiting

Clearance Mechanisms in Atypical Neurodegenerative Diseases (PeptiClear)

Neurodegenerative Diseases | Frontotemporal Degeneration

Germany
Assistance Publique - Hôpitaux de Paris
Gustave Roussy, Cancer Campus, Grand Paris; Institut Curie; CarThera

Recruiting

Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients (SONOKID)

Malignant Glioma | Embryonal Tumor | Malignant Brain Tumor

France
Neuromed IRCCS
University of Rome Tor Vergata

Not yet recruiting

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

Healthy | Neuromyelitis Optica | Relapsing-Remitting Multiple Sclerosis (RRMS)

Italy
Ludwig-Maximilians - University of Munich

Recruiting

Amyloid-β Clearance Mechanisms in Alzheimer's Disease (AmyClearAD)

Alzheimer's Disease (AD)

Germany
Paracelsus Medical University

Recruiting

Glymphatic Pathway in Brain Imaging

Glymphatic System

Germany

Search clinical trials for: bood brain barrier

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