Search clinical trials for: donor specific antibodies

Total 11580 results

Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Peking University People's Hospital

Not yet recruiting

Kinectics of Donor-specific Anti-HLA Antibody After HLA-incompatible Allogeneic Haematopoietic Stem Cell Transplantation

Haematological Malignancy
Liverpool University Hospitals NHS Foundation Trust
Kidney Research United Kingdom

Not yet recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients (HLA-AB)

Frailty | Kidney Transplant Rejection | Renal Transplant | Diagnosis | Kidney Transplant; Complications | Kidney Transplant | Renal Transplant Failure | Transplant Dysfunction

United Kingdom
Tongji Hospital
Anapure BioScience; Caibo MedTech; SKM BioTech

Recruiting

Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients (TTV)

Kidney Transplant Infection | Kidney Transplant Rejection | Immunosuppression | Virus

China
CareDx

Not yet recruiting

HeartCare Immuno-optimization in Cardiac Allografts (MOSAIC) (MOSAIC)

Immunosuppression | Allograft | Heart Transplant
University Hospital, Tours

Not yet recruiting

Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies (INSTEAD)

Renal Transplant Rejection | Induction Therapy
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Renal Allograft Recipients

France, Germany, Spain, United Kingdom, Italy, Netherlands, Belgium, United States
University Hospital, Toulouse

Recruiting

Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy (RAIPONS)

Kidney Transplantation | Graft Failure

France
Vastra Gotaland Region
Karolinska University Hospital; The Swedish Research Council; Uppsala University...

Recruiting

TocIlizumab in Chronic Antibody-mediated Rejection in Kidney Transplant Recipients (INTERCEPT)

Antibody-mediated Rejection

Sweden
King Faisal Specialist Hospital & Research Center

Recruiting

Standard Induction With Basiliximab Versus No-Induction in Low Immunological Risk Kidney Transplant Recipients

Kidney Transplantation

Saudi Arabia
Institute for Clinical and Experimental Medicine

Recruiting

rATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT) (INHIBIT)

Kidney Transplantation

Czechia
University of Zurich

Recruiting

Nanoparticle for DSA Removal

Kidney Failure | Presence of Donor Specific Antibodies

Switzerland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Re-evaluation of Donor-specific Anti-HLA Alloantibodies Immunoassay After Organ Transplantation, From Antigen Level to Epitope Level (ACORG-HLA)

Organ Transplantation
Hannover Medical School

Recruiting

Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation

Lung Transplantation | Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies

Germany
University Hospital, Strasbourg, France

Recruiting

DSA Intragraft in Lung Transplantation: Diagnostic and Prognostic Value in Antibody Mediated Rejection

Lung Transplant Recipient | Antibody Mediated Rejection | Donor Specific Antibodies

France
University of Rome Tor Vergata

Completed

DE NOVO DONOR SPECIFIC ANTIBODIES AFTER KIDNEY TRANSPLANTATION: SINGLE-CENTER RETROSPECTIVE STUDY (PTV-DSAaKT)

Immunosuppression | Kidney Transplant; Complications
Stanley Jordan, MD

Active, not recruiting

Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Kidney Failure, Chronic | End-Stage Renal Disease | Kidney Transplant; Complications | Antibody-mediated Rejection | Kidney Transplant Failure and Rejection | Transplant;Failure,Kidney | Transplant Glomerulopathy

United States
Erasmus Medical Center

Completed

Impact of Donor-Specific Antibodies in (Highly-) Immunized Living Donor Kidney Transplant Recipients

Renal Failure
Massachusetts General Hospital
Genentech, Inc.; Biogen

Withdrawn

Rituximab Therapy for Patients on Kidney Transplant Waiting List With Positive Donor Specific Crossmatch to Living Donor

Kidney Insufficiency
Cedars-Sinai Medical Center
Veloxis Pharmaceuticals

Active, not recruiting

Comparison of Tacrolimus Extended-Release (Envarsus XR) to Tacrolimus Immediate-Release in HLA Sensitized Kidney Transplant Recipients

Kidney Transplant Rejection

United States
CareDx

Withdrawn

KidneyCare Immuno-optimization in Renal Allografts (KIRA)

Immunosuppression | Kidney Transplant | Allograft
Washington University School of Medicine
Bristol-Myers Squibb; National Heart, Lung, and Blood Institute (NHLBI)

Completed

Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation

Lung Transplant Rejection | Antibody-mediated Rejection

United States
Seoul National University Hospital
GC Biopharma Corp; Severance Hospital

Completed

IVIG/Rituximab vs Rituximab in Kidney Transplant With de Novo Donor-specific Antibodies

Renal Transplant

Korea, Republic of
University of Wisconsin, Madison

Terminated

Identification of Donor Specific B Cells and Antibody Mediated Rejection

Sensitized Kidney Transplant Recipients

United States
Cedars-Sinai Medical Center
Alexion Pharmaceuticals

Completed

The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation (DUET)

Cardiac Allograft Vasculopathy | Antibody-mediated Rejection | Left Ventricular Dysfunction | Hyperacute Rejection of Cardiac Transplant | Heart Graft Dysfunction

United States
University Hospital, Lille

Completed

Interest of the Donor-specific Antibodies After Liver Transplantation (vaLIDLIver)

Liver Transplant

France
Assistance Publique - Hôpitaux de Paris
CSL Behring; Association ASLUMARE

Completed

Effect of Privigen Against Graft Loss (InAuGuRAL)

Kidney Transplantation

France
Medical University of Warsaw
Ministry of Science and Higher Education, Poland

Active, not recruiting

Donor-specific Anti-HLA Antibodies Monitoring in Kidney Transplant Recipients

Kidney Transplant Rejection

Poland
Heidelberg University

Unknown

Multicenter CTS Pre-and Post-Transplantation Covid-19 Serum Studies

Covid19 | Liver Transplant; Complications | Kidney Transplant; Complications | Kidney Transplant Failure and Rejection | Liver Transplant Failure and Rejection

Germany
The Methodist Hospital Research Institute
Veloxis Pharmaceuticals

Withdrawn

Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant

Acute Rejection of Renal Transplant | Kidney Disease, End-Stage | Donor Specific Antibodies
University of Colorado, Denver
Veloxis Pharmaceuticals

Terminated

Pilot Study of Treatment for Subclinical AMR (Antibody-mediated Rejection) in Kidney Transplant Recipients

Kidney Transplant Rejection

United States
Fundación Pública Andaluza para la Investigación...
Sociedad Andaluza de Trasplantes de Organos y Tejidos

Completed

Steroid Withdrawal and Donor-specific Anti-HLA Antibodies in Renal Transplant Patients

Renal Transplant Rejection | Other Complication of Kidney Transplant

Spain
University Hospital, Grenoble

Unknown

Treatment of Chronic Active Antibody Mediated Rejection After Kidney Transplantation by Double-Filtration PlasmaPheresis or Plasma Exchange (DFPP)

Kidney Transplantation | Antibody Mediated Rejection

France
Rigshospitalet, Denmark
Karolinska Institutet; Oslo University Hospital; Helsinki University Central... and other collaborators

Unknown

Donor Specific HLA Alloantibodies in Liver Transplantation

Complication of Transplanted Liver

Denmark, Finland, Norway, Sweden
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation in Children

Completed

Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function

Pediatric Heart Transplantation | Pediatric Heart Transplant Recipients

United States, Canada
Assistance Publique - Hôpitaux de Paris

Unknown

Immunization Anti HLA in the Liver Transplant Recipients (DSATH) (DSATH)

Liver Transplantation | Graft Failure

France
University Hospital, Toulouse

Completed

Impact of Anti-HLA Donor-specific Antibodies in ABO-incompatible Kidney Transplantation (A3)

Kidney Transplant

France
London Health Sciences Centre

Active, not recruiting

Antibodies and Liver Retransplantation

Antibody-mediated Rejection | Liver Transplant Failure
Paris Translational Research Center for Organ Transplantation

Completed

Complement-activating Anti-human Leucocyte Antigen Donor Specific Antibodies in Solid Organ Transplantation

Organ Transplant Recipients
Gladwin, Mark, MD

Terminated

Endothelial Injury and Development of Coronary Intimal Thickening After Heart Transplantation

Cardiac Allograft Vasculopathy | Antibody Mediated Rejection

United States
Cedars-Sinai Medical Center

Completed

A Safety Study of Tocilizumab to Improve Transplant Rates in Highly Sensitized Patients Awaiting Kidney Transplantation

End Stage Renal Disease (ESRD)

United States
East Carolina University
Novartis Pharmaceuticals

Completed

Reducing Donor Specific Antibody (DSA) Strength in Maintenance Kidney Transplant Recipients (DSA Study)

Transplant; Failure, Kidney

United States
National Cancer Institute (NCI)

Completed

Active Immunization of Sibling Bone Marrow Transplant Donors Against Purified Myeloma Protein of the Recipient Undergoing Allogeneic Bone Marrow Transplantation

Multiple Myeloma | Graft vs Host Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
MedMira Laboratories Inc.

Not yet recruiting

Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario.

Treponema Pallidum

Canada
Ciusss de L'Est de l'Île de Montréal

Recruiting

Donor-Derived EBV-Specific T Cells for Life Threatening EBV-lymphoma (OLIP-EBV-TCL-01-HMR01)

EBV Associated Lymphoma

Canada
IRCCS Burlo Garofolo

Recruiting

Validation of a New Innovative Method for Specific Marker Detection in Celiac Disease

Celiac Disease in Children

Italy
University Hospital, Rouen

Not yet recruiting

Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R) (BELA-M-R)

Kidney Transplant Rejection
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Hospices Civils de Lyon

Recruiting

Brain MRI Longitudinal Volumetric Characteristics Associated With Outcomes of CASPR2-Limbic Encephalitis (C2-MRI)

Autoimmune Encephalitis Associated With Anti-CAPR2 Antibodies

France

Search clinical trials for: donor specific antibodies

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