Search clinical trials for: drug biotransformation

Total 260509 results

Universidade Federal do Rio de Janeiro

Recruiting

Effectiveness of Melissa Officinalis for the Treatment of Probable Sleep Bruxism in Children and Adolescents

Adolescent | Children | Temporomandibular Joint Disorders | Sleep Bruxism

Brazil
Zhejiang ACEA Pharmaceutical Co. Ltd.

Completed

[14C] Study on Mass Balance and Biotransformation of STI-1558 in Healthy Chinese Adult Male Subjects

COVID-19

China
Daewoong Pharmaceutical Co. LTD.
Shanghai Haini Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study to Investigate the Mass Balance and Biotransformation of [14C]DWP14012 in Healthy Chinese Male Subjects

Phase 1 Study, Healthy Volunteers

China
Sunshine Lake Pharma Co., Ltd.

Completed

Study on the Body Mass Balance and Biotransformation of [14C]-HEC585

Healthy Volunteer

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

Study to Investigate the Mass Balance and Biotransformation of SIM0417 in Healthy Adult Chinese Male Participants

Healthy Male Volunteers

China
Children's Mercy Hospital Kansas City

Withdrawn

In Vivo Assessment of Histamine Pharmacodynamics

Histamine Biotransformation

United States
Allist Pharmaceuticals, Inc.

Completed

Study Evaluating the Mass Balance And Biotransformation of Single Dose[14C] AST2818 in Chinese Healthy Male Volunteers

Healthy Male Volunteers

China
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body

Healthy

United States
Orion Corporation, Orion Pharma
Bayer

Completed

Mass Balance, Pharmacokinetics, Biotransformation and Bioavailability Study of ODM-201 in Healthy Male Subjects (ARIADME)

Healthy

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
University of Nottingham; Quadram Institute Bioscience

Completed

Where is the Initial Site of Biotransformation of Folates in Humans? (FOLTIPS)

Healthy

United Kingdom
Institut fuer anwendungsorientierte Forschung und...

Completed

Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

Membrane Transport | Drug Biotransformation

Germany
Quadram Institute Bioscience
University of Nottingham

Completed

Estimation of Plasma Folate Apparent Volume of Distribution in Adults (FOLCAN)

Healthy

United Kingdom
Virginia Commonwealth University
University of Louisville

Completed

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Sleep Apnea

United States
Virginia Polytechnic Institute and State University
Medical University of South Carolina; National Cancer Institute (NCI); University...

Not yet recruiting

Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study (MUSC-R 3a)

Cigarette Smoking | Nicotine Vaping

United States
Suez Canal University

Recruiting

Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial

Postoperative Pain | Symptomatic Irreversible Pulpitis

Egypt
German University in Cairo
Prof. Mohamed Hassan Solayman, Clinical pharmacy Department, German University... and other collaborators

Not yet recruiting

Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency

Psychiatric Disorder
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High Risk COPD Population

Chronic Obstructive Pulmonary Disease | Multimorbidity | Population Medicine
IRCCS San Raffaele Roma

Recruiting

NK-ORB Expression of Mu Receptor on Lymphocytes in Rehabilitation (NK-ORB)

Fibromyalgia

Italy
Merck Sharp & Dohme LLC

Not yet recruiting

Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)

Essential Thrombocythemia
Taichung Veterans General Hospital
Chang Gung Memorial Hospital; National Cheng-Kung University Hospital; E-DA Hospital and other collaborators

Recruiting

Taiwan Severe Asthma Biologic Registry (TARGET)

Asthma | Pulmonary Disease

Taiwan
Shanghai Chest Hospital
Novartis; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; BeiGene

Not yet recruiting

Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC

KRAS Mutation-Related Tumors | Advanced Lung Cancer | Refractory Tumor

China
Assiut University

Not yet recruiting

Clinical Outcomes and Prognostic Factors in Multiple Myeloma Patients

Multiple Myeloma
Peking Union Medical College Hospital

Not yet recruiting

Effects of Selenium Towards Type 2 Diabetes

Type 2 Diabetes

China
Shanghai Mental Health Center

Recruiting

Paired-pulse rTMS Treatment for Methamphetamine Use Disorder Based on the Frontopolar-Cerebellum

Amphetamine Use Disorders

China
University of Massachusetts, Worcester

Not yet recruiting

Preventing T2DM After GDM With Immediate Postpartum Screening and Treatment

Type 2 Diabetes | Gestational Diabetes

United States
University of Rochester
National Institute on Drug Abuse (NIDA); Medical University of South Carolina; Ohio State University

Not yet recruiting

Opioids and Loneliness

Opioid Use Disorder | Loneliness | Social Isolation
Sohag University

Recruiting

Pulse Steroid Injection in Refractory Rheumatoid Arthritis

Active Rheumatoid Arthritis

Egypt
Beijing 302 Hospital

Recruiting

Sequential Combination Therapy With PD-1 Antibody and Peg-IFNα in CHB Patients

Chronic Hepatitis B

China
University of Parma
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Federico II University; University... and other collaborators

Recruiting

Use of miRNAs in Growth Hormone Deficiency (GHD) (GH-miRNA2)

Growth Hormone Deficiency

Italy
Hospices Civils de Lyon

Not yet recruiting

Mind-wandering and Predictive Processes in Narcolepsy: a Putative Mechanism Through Covert REM Intrusions (NARCOWANDERING)

Hypersomnolence | Idiopathic Hypersomnia | Narcolepsy Type 1

France
Impactiv, Inc.
Duke University

Not yet recruiting

Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.

Muscle Weakness | PreDiabetes | Muscle Loss | Older Adult

United States
University Hospital, Tours
Fondation Ildys

Not yet recruiting

Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial (DIAPASOM)

Cystic Fibrosis

France
Azienda Ospedaliera di Perugia

Recruiting

Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery

Pain | Trismus | Edema Face | Extracting Own Teeth | Molar, Fourth

Italy
Assiut University

Not yet recruiting

Frequency of Metabolic Dysfunction Associated Fatty Liver Disease in Patients With Acute Coronary Syndromes

Fatty Liver
Kanuni Sultan Suleyman Training and Research Hospital

Not yet recruiting

Assessing the Accuracy of ChatGPT-4 in Interpreting Arterial Blood Gas Results

Blood Gases

Turkey
Université de Sherbrooke
Nestlé Health Science

Not yet recruiting

Reduced Carbohydrates + Ketogenic Supplement on Energy Metabolism (SAGE-2)

Healthy Aging

Canada
Min Yan, MD
Beijing Biostar Pharmaceuticals Co., Ltd.

Recruiting

Utidelone Capsule Plus Capecitabine (CAP) for Metastatic Breast Cancer

Breast Cancer Recurrent

China
Memorial Sloan Kettering Cancer Center
TransThera Sciences

Recruiting

A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

Prostate Cancer

United States
Coherus Biosciences, Inc.

Not yet recruiting

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer (TRANSPARENT)

Nasopharyngeal Cancer Recurrent
University Hospital Ostrava

Recruiting

Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

Hepatitis E

Czechia
Universidad Rey Juan Carlos

Recruiting

Effectiveness of Non-invasive Neuromodulation in Patients With Long-COVID

Post-acute COVID-19 Syndrome | Long-COVID

Spain
University of Chicago

Not yet recruiting

IntraCERvical Balloon Catheter in the Setting of Induction of Labor for Fetal Loss or Abortion (CERBI)

Fetal Death | Induction of Labor Affected Fetus / Newborn | Abortion, Complete
Shanghai Mental Health Center

Recruiting

Closed-loop cTBS for the Core Clinical Features of Methamphetamine Use Disorder

Amphetamine Use Disorders

China
Vanderbilt University Medical Center

Not yet recruiting

Statin Reminders for Improving Prescribing in Primary Care

Education | Cholesterol, Elevated | Clinical Decision Support

United States
Aalborg University

Recruiting

Feasibility of a Home Exercise Program With the Addition of a Corticosteroid Injection in Patients With Lateral Hip Pain

Greater Trochanteric Pain Syndrome

Denmark
Shanghai Mental Health Center

Not yet recruiting

Emotional Attention Bias Modification and Targeted Memory Reactivation in Alcohol Use Disorder

Alcohol Use Disorder
Washington State University
Managed Health Connections

Recruiting

Automated Reinforcement Management Systems, Phase II (ARMS II)

Alcohol Use Disorder

United States
Central Institute of Mental Health, Mannheim

Not yet recruiting

Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial (MECT-RESIST)

Schizophrenia | Treatment Resistant Schizophrenia

Germany
Medical University of South Carolina

Recruiting

Post-stroke Pain taVNS

Stroke | Pain

United States
Kocaeli City Hospital
Health Institutes of Türkiye (TUSEB)

Not yet recruiting

Effect of Sevoflurane and Desflurane on Heme Oxygenase-1 Expression in Elective Cholecystectomy

Cholecystitis, Chronic

Turkey

Search clinical trials for: drug biotransformation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Jamaica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations