Search clinical trials for: drug conversion

Total 259815 results

Cancer Institute and Hospital, Chinese Academy...

Recruiting

Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer (NEXUS-2)

Esophagus Cancer

China
Mansoura University

Recruiting

Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years

Nephrotic Syndrome in Children

Egypt
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine as Conversion Therapy of Locally Advanced Colorectal Cancer

Colorectal Cancer

China
Harbin Medical University

Not yet recruiting

HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer

Biliary Tract Cancer
Closed Loop Medicine
Pharmanovia

Recruiting

Personalised Dose Optimisation of Zestril Supported by the Digital Blood Pressure Diary in a Primary Care Environment in England: Pragmatic Observational Pilot Study for Remote Hypertension Treatment (OptiZest)

Uncomplicated Hypertension

United Kingdom
Wuhan Union Hospital, China

Not yet recruiting

Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Cancer Non-resectable | Pancreatic Ductal Adenocarcinoma, PDAC

China
Academisch Ziekenhuis Maastricht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Timely Recovery After Subclinical Heart Failure (TREASURE)

Heart Failure | Diastolic Dysfunction

Netherlands
Qilu Hospital of Shandong University

Recruiting

Chemotherapy With Cetuximab as Conversion Therapy in RAS/BRAF WT Unresectable Liver Metastasis Right-sided Colon Cancer

Colon Cancer

China
Arab Contractors Medical Centre

Not yet recruiting

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy (BASiC-CIC)

Chemotherapy Induced Systolic Dysfunction

Egypt
University Hospital, Rouen

Not yet recruiting

Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R) (BELA-M-R)

Kidney Transplant Rejection
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Heart Failure | Mitral Regurgitation

China
Servier Russia

Not yet recruiting

Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy (TRIPTYCH) (TRIPTYCH)

Arterial Hypertension | HTN
Ain Shams University

Recruiting

Alpha-lipoic Acid in Diabetic Nephropathy

Type 1 Diabetes

Egypt
The Essence of Integrative Health and Medicine...

Not yet recruiting

Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues (PNMD)

Dementia | Anxiety | Bipolar Disorder | Chronic Fatigue Syndrome | Stress Disorder | ADHD - Combined Type | Dissociative Disorder | Schizoaffective Disorder, Bipolar Type
Hairong Liu

Not yet recruiting

Envafolimab Combined With Chemotherapy in Neoadjuvant and Conversion Therapy for Head and Neck Squamous Cell Carcinoma

Efficacy and Safety
Peking Union Medical College Hospital

Recruiting

Cadonilimab and Lenvatinib for Conversion Therapy in Unresectable Hepatocellular Carcinoma

Cadonilimab and Lenvatinib

China
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Ze-yang Ding, MD
Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver Cancer (CCGLC)

Recruiting

DEB-TACE, Lenvatinib and Anti-PD(L)1 Antibody as Conversion Therapy for Intrahepatic Cholangiocarcinoma (CCGLC-009)

Cholangiocarcinoma Non-resectable

China
Ze-yang Ding, MD
Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver Cancer (CCGLC)

Recruiting

Combined HAIC, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma (CCGLC-013)

Cholangiocarcinoma Non-resectable

China
Brigham and Women's Hospital

Not yet recruiting

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease (SubPA-DKD)

Chronic Kidney Diseases | Type 2 Diabetes

United States
Tongji Hospital
Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver Cancer (CCGLC)

Recruiting

Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma (CCGLC-012)

Cholangiocarcinoma Non-resectable

China
Tongji Hospital
Geneplus-Beijing Co. Ltd.

Recruiting

Combined HAIC, Lenvatinib and Cadonilimab as Conversion Therapy for Unresectable Hepatocellular Carcinoma (CCGLC-011)

Hepatocellular Carcinoma Non-resectable

China
Assiut University

Not yet recruiting

Treatment of Patients With Diabetic Kidney Disease

Diabetic Kidney Disease
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Cadonilimab Plus mFOLFIRINOX as Conversion Therapy in LAPC

Pancreatic Cancer

China
Beijing Tsinghua Chang Gung Hospital

Not yet recruiting

Early Conversion of Prolonged-release Tacrolimus in Liver Transplantation.

Liver Transplantation
Peking Union Medical College
Peking University Hospital of Stomatology

Recruiting

Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing

Precision Therapy | Locally Advanced or Recurrent/Metastatic Salivary Gland Carcinoma | Neoadjuvant or Conversion Therapy

China
Natural Wellness Egypt

Not yet recruiting

NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial

Essential Hypertension
Population Health Research Institute

Not yet recruiting

Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Surgery (FLIP-AF)

Atrial Fibrillation | Surgery
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Xiaofeng Chen

Recruiting

XELOX Combined With Fruquintinib and Sintilimab Regimen Conversion Therapy for Gastric Cancer/Gastroesophageal Junction Adenocarcinoma Only With Liver and/or Retroperitoneal Lymph Node Metastasis, a Prospective Single-arm, Multicenter Study

Gastric Cancer/Gastroesophageal Junction Adenocarcinoma

China
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

Maternal Treatment With ACE-inhibitors and Breastfeeding: a Mono-centric Study on the Exposure Through Breast Milk

Heart Failure | Hypertension | Proteinuria | Breast Feeding

Belgium
University of Fribourg
Insel Gruppe AG, University Hospital Bern

Recruiting

The Role of Oxytocin and Interoception in Functional Neurological Disorder

Functional Neurological Disorder

Switzerland
First Affiliated Hospital of Zhejiang University

Recruiting

Toripalimab in Combined With Cetuximab，Chemotherapy for Conversion Therapy of Locally Nonresectable OCSCC

Squamous Cell Carcinoma of Head and Neck

China
Sun Yat-sen University
First People's Hospital of Foshan; The First Affiliated Hospital, Guangzhou... and other collaborators

Recruiting

Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC (HAIC)

Hepatocellular Carcinoma | Chemotherapy Effect | Chemotherapeutic Toxicity

China
China National Center for Cardiovascular Diseases
Peking University First Hospital; Beijing Children's Hospital

Recruiting

Study of Drug Therapy for Pediatric Heart Failure

Heart Failure Congenital

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair

Congenital Mitral Insufficiency

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation

Congenital Mitral Insufficiency

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Fruquintinib as First Line Treatment in Patients With Recurrent Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Sun Yat-sen University

Not yet recruiting

Surufatinib and Serplulimab Combined With AG Regimen Compare With AG Regimen as Conversion Therapy for Patients With Locally Advanced Pancreatic Cancer (SAGE)

Locally Advanced Pancreatic Cancer

China
Ain Shams University

Not yet recruiting

Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome.

Nephrotic Syndrome
Chongqing Medical University
Chinese PLA General Hospital; Tianjin Medical University General Hospital; Chinese...

Recruiting

Primary Aldosteronism LC-MS/MS-specific Cutoffs (PM)

Primary Aldosteronism

China
Medical University of Graz

Recruiting

Observational Study on "Functional Overlay" in Patients With Movement Disorders

Parkinson Disease | Dystonia | Conversion Disorder | Tremor

Austria
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Fujian Medical University

Not yet recruiting

Envollizumab Combined With Fruquintinib and SOX Versus SOX for Conversion Therapy in Advanced Gastric Cancer

Gastric Cancer
Tianjin Medical University Cancer Institute and...

Recruiting

HAIC Combined With Durvalumab, Tremelimumab and Bevacizumab as Conversion Therapy for Potentially Resectable Hepatocellular Carcinoma

Unrescetable Hepatocellular Carcinoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Surgical Conversion of Candonilimab (AK104) Plus Paclitaxel, S-1 and Apatinib for Unresectable Advanced G/GEJ Cancer

Gastric Cancer

China
October 6 University
Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Dapagliflozin on Secondary Mitral Regurgitation

Dilated Cardiomyopathy

Egypt
Zhejiang University

Recruiting

A Phase II Trial to Evaluate the Efficiency and Safety of Serplulimab Plus Chemotherapy as Conversion Therapy in NSCLC

Unresectable Lung Non-Small Cell Carcinoma

China
Fujian Medical University Union Hospital

Not yet recruiting

Immunotherapy Plus Chemotherapy vs. Chemoradiotherapy for Thoracic Squamous Esophageal Carcinoma

Chemotherapy | Radiation Therapy

China
Wuhan Union Hospital, China
Peking University First Hospital

Recruiting

High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program

Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus, Type 2

China

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