Search clinical trials for: drug resistant

Total 260363 results

Georgiamune Inc

Not yet recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Solid Tumor | Melanoma Stage IV
Centre Hospitalier Universitaire de Besancon
Groupement Interrégional de Recherche Clinique et d'Innovation

Not yet recruiting

Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers (CARE)

Metastatic Colorectal Cancer

France
Dartmouth-Hitchcock Medical Center
Dartmouth College; University of Massachusetts, Worcester

Not yet recruiting

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application (SONATA)

Epilepsy | Refractory Epilepsy | Music

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)

Advanced Solid Tumor

United States, Germany
Beneficência Portuguesa de São Paulo
Ministry of Health, Brazil

Not yet recruiting

Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)

Central Nervous System Infections
Peking Union Medical College Hospital
Shengjing Hospital; The Affiliated Hospital of Qingdao University; Children's... and other collaborators

Recruiting

Belimumab After Rituximab in Resistant Primary Juvenile SS (BRRPJS)

Pediatric ALL | Sjogren's Syndrome

China
Henan Cancer Hospital
Kingbio Medical (Beijing) Co., Ltd.

Recruiting

Patient-derived Organoid Drug Sensitivity Guided Treatment for Drug-resistant Recurrent Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Swiss Group for Clinical Cancer Research

Not yet recruiting

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

Switzerland
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Shanghai Zhongshan Hospital

Not yet recruiting

The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis

Glucocorticoid Resistant ICIs-related Myocarditis
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

SHR-A1921 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer

Ovarian Cancer

China
Abderrahmane Mami Hospital

Recruiting

Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units (NOSOREA3)

Critical Illness | Cross Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection

Tunisia
Assiut University

Not yet recruiting

Performance of Xpert MTB/RIF and XDR Assay for Diagnosis of Pulmonary Tuberculosis and Resistant Pulmonary TB

Tuberculosis, Pulmonary
NaviFUS Corporation
NaviFUS US LLC

Not yet recruiting

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

Epilepsy | Drug Resistant Epilepsy

United States
Elizabeth Anne Thiele
Ajinomoto Co., Inc.; Ajinomoto USA, INC.

Not yet recruiting

Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy

Drug Resistant Epilepsy | Refractory Epilepsy

United States
Cairo University

Not yet recruiting

Antibiotic Use and Resistance KAP Among Dental Interns

Antibiotic Side Effect | Antibiotic Resistant Infection
AstraZeneca
Merck Sharp & Dohme LLC

Recruiting

Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed) (PROceed)

Metastatic Castration-resistant Prostate Cancer

Germany
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
University Hospital, Ghent
Filament Health

Recruiting

Psilocybin for Hospitalized Patients With Treatment-resistant Depression (PSIHOS-D)

Treatment Resistant Depression

Belgium
Medical University of Warsaw

Recruiting

Tocilizumab in Corticosteroid-Resistant Graves' Orbitopathy (Thyroid Eye Disease)

Thyroid Eye Disease | Ophthalmopathy | Orbitopathy, Graves

Poland
Przemyslaw Kunert
NaoX Technologies; Warsaw Medical University Clinical Center; Departments and...

Not yet recruiting

Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes

Epilepsy | Drug Resistant Epilepsy | Focal Epilepsy

Poland
Nova Scotia Health Authority

Not yet recruiting

Enhancing Epilepsy Management With Precision Deep Brain Stimulation (EPI-BOOST)

Epilepsy, Drug Resistant

Canada
Beijing 302 Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.; Chinese Academy of...

Not yet recruiting

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody

Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
IRCCS Eugenio Medea

Recruiting

Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy

Epilepsy | Angelman Syndrome | Dup15q Syndrome

Italy
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Prostatic Neoplasms, Castration-Resistant

Israel, Taiwan
University of California, Los Angeles

Not yet recruiting

MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents

Psychotherapy | Adolescents | PTSD, Post Traumatic Stress Disorder

United States
Infectious Diseases Research Collaboration, Uganda
London School of Hygiene and Tropical Medicine; Radboud University Medical...

Not yet recruiting

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy (SPARTAN)

Falciparum; Malaria

Uganda
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals

Not yet recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Breast Cancer | Triple Negative Breast Cancer | Relapse | Resistant Cancer

United States
SL VAXiGEN

Recruiting

Phase 1 Study Evaluating Safety and Tolerability of SL-T10, GX-I7, and Pembrolizumab Triple Combination in mCRPC.

Metastatic Castration-resistant Prostate Cancer (mCRPC)

Korea, Republic of
University Health Network, Toronto
Centre for Addiction and Mental Health

Recruiting

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin (PSI-1V2)

Depression | Mood Disorders | Major Depressive Disorder | Treatment-Resistant Depression

Canada
Synergia Medical

Not yet recruiting

A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl (AURORA)

Drug Resistant Epilepsy
National Cheng-Kung University Hospital

Not yet recruiting

Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate

Schizophrenia | Schizo Affective Disorder | Symptom, Cognitive
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
Assistance Publique Hopitaux De Marseille
Neuroelectrics Corporation; CRMBM-CEMEREM; Institut National de la Santé Et de...

Not yet recruiting

Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic (GALVANI GS-3)

Epilepsy | Drug Resistant Epilepsy

France
Fondazione del Piemonte per l'Oncologia

Recruiting

INSIDE: Identification of Genomic Screening Pathways in Cancer Patients With DNA Repair Alterations (INSIDE)

Prostate Cancer

Italy
Bayer

Not yet recruiting

An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea

Non-metastatic Castration-resistant Prostate Cancer | Metastatic Hormone-sensitive Prostate Cancer

Korea, Republic of
Zhen-Yu Ding

Recruiting

DC Combined With ICIs in the Treatment of Advanced Lung Cancer Resistant to ICIs

Lung Cancer

China
Rohan Garje
Janssen Scientific Affairs, LLC

Not yet recruiting

177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancer (LUNAAR)

Castration-resistant Prostate Cancer | Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United States
European Institute of Oncology

Recruiting

Response Evaluation of Cancer Therapeutics in Metastatic Castration-Resistant Prostate Cancer to the Bone (RESPECT)

Castration-resistant Prostate Cancer

Italy
Emory University
Centers for Disease Control and Prevention

Not yet recruiting

Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT)

Multi-Drug Resistant Organism Colonization

United States
Cybrexa Therapeutics

Not yet recruiting

A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

Platinum-resistant Ovarian Cancer | Refractory Ovarian Carcinoma
Hospital Universitario Mayor Mederi
Universidad del Rosario

Not yet recruiting

Predictive Factors Associated to Bile Cultures and Antibiogram Resistance in Patients With Laparoscopic Cholecystectomy (BACILO)

Antibiotic Resistant Strain | Biliary Infection
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Ketogenic Diet in Pediatric Intractable Epilepsy

Epilepsy Intractable | Epilepsy in Children

China
IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods

Drug Resistant Bacterial Infection

Italy
Danone Nutricia SpA Società Benefit

Recruiting

Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients

Autism Spectrum Disorder | Drug Resistant Epilepsy | Chronic Migraine | Brain Tumor, Pediatric

Italy
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

Ovarian Cancer | Epithelial Ovarian Cancer | Ovary Neoplasm | Recurrent

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy (BLUELIGHTVNS)

Refractory Epilepsy

Belgium
Dana-Farber Cancer Institute
Novartis

Not yet recruiting

LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer

Prostate Cancer | Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United States

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