Search clinical trials for: drug-drug interaction

Total 2873 results

Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

Effect of Clarithromycin and Rifampicin on the Pharmacokinetics of XZP-3287 in Healthy Subjects

Healthy

China
University Hospital, Bordeaux
Synapse bv

Not yet recruiting

Drug Interactions in Hospital Information System. The PRoSIT System.. (PROSIT)

Drug Interaction

France
University of California, San Francisco
Food and Drug Administration (FDA)

Active, not recruiting

Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP) (BCRPmarker)

Healthy Volunteers

United States
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
Obafemi Awolowo University
University of Liverpool

Completed

Pharmacokinetic Interaction Between Nitazoxanide and Atazanavir/Ritonavir in Healthy Volunteers

Drug Interaction

Nigeria
Enanta Pharmaceuticals, Inc

Completed

Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects

COVID-19

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects.

COVID-19

United States
Pfizer

Completed

A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer (PROFILE 1001)

Systemic Anaplastic Large-Cell Lymphoma | Non-Small Cell Lung Cancer ALK-positive | Non-Small Cell Lung Cancer c-Met Dependent | Non-Small Cell Lung Cancer ROS Marker Positive | Advanced Malignancies Except Leukemia

United States, Korea, Republic of, Australia, Japan
Maastricht University
European Commission

Completed

Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers (REPO-STROKE1)

Safety Issues | Drug Drug Interaction

Germany
Pfizer

Completed

A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants

Healthy Participants

United States
Novartis Pharmaceuticals

Completed

A Real-world Analysis of Concomitant Medication Use Among Metastatic Breast Cancer Patients Treated With CDK4/6 Inhibitors

Metastatic Breast Cancer

United States
University Hospital, Basel, Switzerland

Completed

Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate (ADA in PiRD)

Rheumatic Diseases

Switzerland, Germany
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy Subjects

RSV Infection

United States
University of California, San Diego
University of California, Los Angeles; GlaxoSmithKline; University of Southern... and other collaborators

Completed

Viral Dynamics and Pharmacokinetics of Abacavir and Tenofovir

HIV Infections

United States
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Enanta Pharmaceuticals, Inc
PRA Health Sciences

Completed

Drug-Drug Interaction Study Between EDP-514, Itraconazole, Carbamazepine, and Quinidine in Healthy Subjects

Hepatitis B

United States
Odonate Therapeutics, Inc.

Terminated

The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-Drug Interaction Study Between Fluconazole and EDP-938 in Healthy Subjects

RSV Infection

United States
University of Zurich
University Hospital, Zürich; Center of Competence Multimorbidity, Zurich

Completed

Therapeutic Conflicts and Multimorbidity

Diabetes Complications | Gastrointestinal Hemorrhage | Multimorbidity

Switzerland
Theravance Biopharma

Completed

Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study

Inflammatory Bowel Disease

United States
Liminal BioSciences Ltd.
Celerion

Completed

Effect of PBI-4050 on the Pharmacokinetics of Midazolam in Heathy Adult Subjects

Healthy

United States
Radboud University Medical Center

Completed

A Drug-drug Interaction Study Between Daclatasvir and Metformin (DATE-3)

Diabetes Mellitus | Hepatitis C | Insulin Resistance

Netherlands
HK inno.N Corporation

Completed

Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male Volunteers

Healthy

Korea, Republic of
Radboud University Medical Center
GlaxoSmithKline

Completed

Pharmacokinetic Study of Posaconazole Boosted Fosamprenavir (EPOS)

HIV Infection | Fungal Infection

Netherlands
Radboud University Medical Center

Completed

Pharmacokinetic Drug-drug Interaction Study Between RaltEgravir and CITALopram in Healthy Subjects (RECITAL). (RECITAL)

Depression | HIV

Netherlands
ViiV Healthcare

Completed

Effect of GSK3640254 on the Pharmacokinetics of a Combination Oral Contraceptive

HIV Infections

United States
Global Alliance for TB Drug Development

Completed

Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam

Tuberculosis

United States
Novartis Pharmaceuticals

Completed

Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212

Cancer

United States, Australia
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects

RSV Infection

United States
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Ciclosporin

Healthy

United Kingdom
Drugs for Neglected Diseases
PhinC Development

Completed

Pharmacokinetic Drug-Drug Interaction Study

Chagas Disease

Argentina
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Montelukast

Healthy

United Kingdom
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Ritonavir

Healthy

United Kingdom
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Midazolam

Healthy

United Kingdom
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Bupropion

Healthy

United Kingdom
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Fluconazole and Quinidine in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and Midazolam

Healthy Subjects

Germany
Novartis Pharmaceuticals

Completed

Drug-drug Interaction Study of Ofatumumab With Bendamustine in Subjects With Indolent B-cell Non-Hodgkin's Lymphoma

Cancer

United States
Spero Therapeutics
Simbec Research; QPS Holdings LLC

Completed

Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741

Healthy Volunteers

United Kingdom
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Eltrombopag and Cyclosporine in Healthy Subjects

Purpura, Thrombocytopenic, Idiopathic

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Intraconazole and Rifampin in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
Xiyuan Hospital of China Academy of Chinese Medical...

Unknown

Mechanism of Drug-drug Interaction Between Salvianolate Injection and Aspirin

Angina, Stable
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers.

NASH

United States
GlaxoSmithKline

Completed

The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects

Nausea and Vomiting, Chemotherapy-Induced

United States
GlaxoSmithKline

Completed

GSK239512 DDI Study

Multiple Sclerosis

Australia
Bayer

Completed

Drug-drug Interaction Study Between Orally Administered Rifampicin and Vilaprisan

Endometriosis

Germany
GlaxoSmithKline

Terminated

GSK2647544 RD, DDI in Healthy Young and Elderly Volunteers

Alzheimer's Disease

United Kingdom
Achieve Life Sciences
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen

Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug -Drug Interaction of SP2086 and Glyburide

Type 2 Diabetes

China

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