Search clinical trials for: fact for different anticancer drugs

Total 414381 results

Genervon Biopharmaceuticals, LLC
Massachusetts General Hospital; Columbia University

Completed

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS) (GALS)

Amyotrophic Lateral Sclerosis

United States
Hoffmann-La Roche

Completed

A Safety and Tolerability Study of Assisted and Self-Administered Subcutaneous (SC) Herceptin (Trastuzumab) as Adjuvant Therapy in Early Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer (SafeHER)

Breast Neoplasms

Hungary, Italy, United Kingdom, Canada, Czechia, Bulgaria, Croatia, Dominican Republic, France, Germany, Greece, Guatemala, Hong Kong, Indonesia, Ireland, Korea, Republic of, Netherlands, Panama, Peru, Poland, Portugal, Slovakia, Spain and more
Muhammet Atilgan
Mustafa Kemal University

Completed

Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants

Bone Loss, Alveolar | Edentulous Jaw | Resorption, Bone

Turkey
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia

United States, Canada, Australia, Switzerland, New Zealand, Puerto Rico
Inonu University

Completed

Different Platelet Concentrates After Gingivectomy and Gingivoplasty Evaluation of Its Effect on Early Wound Healing.

Wound Heal | Gingival Enlargement | Gingival Overgrowth | Platelet Rich Fibrin

Turkey
Northwestern University
Novartis

Completed

Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens

End Stage Renal Failure With Renal Transplant

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Genistein, Gemcitabine, and Erlotinib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United States
EMS

Withdrawn

A Randomized Study Assess the Safety and Efficacy of Tacrolimus vs Prograf® in Renal Transplantation Treatment

Renal Transplant

Brazil
Emory University
Novartis

Completed

Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer

Thyroid Cancer

United States
GlaxoSmithKline

Completed

A Study to Investigate the Safety and Immunogenicity of Different Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) Administered to Healthy Adults 18 to 40 Years of Age

Infections, Meningococcal

Germany, Canada, Australia, Belgium, Italy
Merck Sharp & Dohme LLC

Completed

A Study of Different Doses of Grazoprevir (MK-5172) Given With Pegylated Interferon Alfa-2b and Ribavirin to Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-038)

Chronic Hepatitis C (CHC)
Assiut University

Unknown

Trans-arterial Chemoembolization in Patients With Hepatocellular Carcinoma: A Study of Different Outcomes and Their Predictive Factors

Liver Cancer

Egypt
Bayer

Completed

A Trial to Learn How Much Rivaroxaban Gets Into the Blood When Taken in Different Forms and How Safe They Are in Healthy Men

Healthy Volunteers

Germany
Bristol-Myers Squibb

Completed

A Study to Evaluate the Pharmacokinetics of Abatacept Converted From Drug Substance by Two Different Processes

Rheumatoid Arthritis

United States
Bayer
Janssen Research & Development, LLC

Completed

Xarelto on Prevention of Stroke and Noncentral Nervous System Systemic Embolism in Treatment-naïve Asian Patients With Non-valvular Atrial Fibrillation (XaMINA)

Atrial Fibrillation

Korea, Republic of, Taiwan
Newcastle University
Penn State University; International Food Policy Research Institute

Unknown

Bioefficacy of Beta-cryptoxanthin From Biofortified Maize (BIOCRYPT)

Vitamin A Deficiency

United Kingdom
GlaxoSmithKline

Terminated

Trial to Evaluate Safety and Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2584786A in Healthy Children

Influenza | Influenza Vaccines

Spain
Tel-Aviv Sourasky Medical Center

Unknown

Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)

Scars | Keloid | Hypertrophic Scar | Scarring
Federal Research Institute of Pediatric Hematology...

Unknown

Rituximab and Abatacept Effectiveness in Differential Treatment of Interstitial Lymphocytic Lung Disease in Children With Primary Immunodeficiencies.

Interstitial Lymphocytic Lung Disease

Russian Federation
Hoffmann-La Roche

Completed

A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer (PERUSE)

Breast Neoplasms

Italy, Netherlands, Belgium, United Kingdom, Argentina, Austria, Brazil, China, Ecuador, Estonia, Finland, France, Germany, Greece, Mexico, Peru, Poland, Portugal, Slovenia, Spain, United Arab Emirates, Canada, Hungary, Israel, Sweden, Tu... and more
E. Sander Connolly
University of Florida; University of Washington; Food and Drug Administration...

Completed

The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage

Aneurysmal Subarachnoid Hemorrhage

United States
Assistance Publique - Hôpitaux de Paris
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Unknown

Pharmacokinetic of Tacrolimus in Paediatric Liver Transplant Patients (TACTHEP)

Liver Transplantation, Child

France
University of Pisa

Completed

RCT With 3 Different Biomaterials for Maxillary Sinus Lift

Alveolar Bone Atrophy

Switzerland
Case Comprehensive Cancer Center

Completed

Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
EMD Serono Research & Development Institute, Inc.
Nordic Bioscience A/S

Completed

A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee (FORWARD)

Osteoarthritis, Knee

Estonia, Romania, Hong Kong, Czechia, Denmark, Poland, Argentina, United States
Air Force Military Medical University, China

Unknown

Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy

Adenoma Colon

China
Novartis Vaccines

Completed

Safety and Immunogenicity of Different Meningitis Vaccine Formulations in Adolescents and Young Adults

Invasive Meningococcal Disease

United States, Poland
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia

Recurrent Chronic Lymphocytic Leukemia

United States
Shahid Beheshti University of Medical Sciences

Completed

An Investigation Into Beneficial Effects of Interferon Beta 1a, Compared to Interferon Beta 1b And The Base Therapeutic Regiment in Moderate to Severe COVID-19: A Randomized Clinical Trial (COVIFERON)

COVID-19

Iran, Islamic Republic of
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
University of Oxford
Novartis; Pfizer; National Health Service, United Kingdom

Completed

Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy (3C)

Kidney Transplantation

United Kingdom
David Drobne

Unknown

Comparison of Two Different Golimumab Dosing Regimens for Ulcerative Colitis

Ulcerative Colitis

Slovenia
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer

Colorectal Cancer

United States, Belgium, Canada, China, Finland, France, Greece, Hungary, Korea, Republic of, Portugal, Spain, Thailand, United Kingdom, Australia, Germany, Israel, Singapore, Italy, Switzerland, Taiwan, New Zealand, Brazil, Hong Kong, Irelan... and more
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Pharmacokinetic Comparability of Guselkumab (CNTO1959) When Delivered by 2 Different Devices and as 2 Formulations in Healthy Participants

Healthy

United States
University of Manitoba

Completed

Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants

Liver Failure

Canada
Chong Kun Dang Pharmaceutical

Unknown

Study to Evaluate the Pharmacokinetics and Tolerability of Tacrolimus in Kidney Transplant Recipients. (PK-TACT)

Kidney Transplant

Korea, Republic of
Pfizer
Novartis; Keyrus Biopharma

Completed

OPALINE : A Study Of Morbidity And Mortality At 2 Years (OPALINE)

Pancreatic Neuroendocrine Tumor, Well Differentiated and Progressive

France
Medical University of South Carolina
Astellas Pharma Inc

Completed

Dosing Requirements of Astagraf XL® in African American Kidney Transplant Recipients

Immunosuppression

United States
Medical University of South Carolina

Completed

Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients

Immunosuppression

United States
Celgene

Completed

Study to Determine Efficacy and Safety of Lenalidomide Plus Low-dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple Myeloma (FIRST)

Multiple Myeloma

Korea, Republic of, United States, France, Belgium, Canada, Spain, United Kingdom, Australia, Italy, New Zealand, China, Portugal, Switzerland, Taiwan, Austria, Greece, Germany, Ireland, Sweden
University of Wisconsin, Madison

Completed

Vitamin A Kinetics and Mathematical Modeling in American Women

Vitamin A Kinetics

United States
University of Maryland, Baltimore
University of Maryland Greenebaum Cancer Center

Completed

Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of Maryland, Baltimore
University of Maryland Greenebaum Cancer Center

Completed

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease

United States
Memorial Sloan Kettering Cancer Center

Completed

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

Neuroblastoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Lymphoma | CD20 Positive | Lymphocytic Neoplasm

United States
Hellenic Cooperative Oncology Group
Novartis

Terminated

Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors

Gastrointestinal Tumors | Pancreatic Neuroendocrine Tumors | Pancreatic Tumors | Gastrointestinal Neuroendocrine Tumors

Greece
Marmara University
National Institute of Allergy and Infectious Diseases (NIAID)

Unknown

Transcriptome and Metabolic Analyses of CHAPLE Disease (CHAPLEOMIC)

Protein-Losing Enteropathies | CD55 - Cluster of Differentiation Antigen 55 Deficiency | Primary Intestinal Lymphangiectasis | Complement Regulatory Factor Defect

Turkey
AstraZeneca

Completed

Phase Ib/II Study of MEDI4736 Evaluated in Different Combinations in Metastatic Pancreatic Ductal Carcinoma

Metastatic Pancreatic Ductal Adenocarcinoma

United States, United Kingdom
Dutch Childhood Oncology Group
Associazione Italiana Ematologia Oncologia Pediatrica; CPH, Czech republic; PINDA... and other collaborators

Unknown

Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia (Interfant06)

Leukemia

United Kingdom, United States, Czechia, Belgium, Germany, Austria, France, Italy, Netherlands

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