Search clinical trials for: formulation; sustained release; modified release; extended release

Total 8057 results

Pfizer
Bristol-Myers Squibb

Completed

Bioavailability Study Comparing Modified Release To Immediate Release Apixaban Tablets In Healthy Volunteers

Thrombosis

United States
Shanghai Mental Health Center
Yantai University

Recruiting

Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Shanghai Mental Health Center

Not yet recruiting

Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression

Somatic Symptom

China
University of Michigan
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetic Study of Single-Dose Modified Release Glipizide in Healthy Volunteers

Human Gastrointestinal Physiology Data

United States
Second Affiliated Hospital of Soochow University

Active, not recruiting

A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease.

Salivation in Parkinson's Disease

China
Johns Hopkins University

Terminated

Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye

Dry Eye

United States
Shanghai Mental Health Center
Yantai University

Completed

Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Lars Tanum
Oslo University Hospital; Haukeland University Hospital; The Hospital of Vestfold and other collaborators

Completed

Long Acting Naltrexone for Opioid Addiction: Focus on Sustained Abstinence and Recovery (NaltRec)

Opioid-use Disorder

Norway
University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
Food and Drug Administration (FDA)
BioPharma Services, Inc

Completed

Drug Interaction With Proton Pump Inhibitors for Nifedipine ER Tablets

Healthy Volunteers

United States
Duke University

Completed

Effect of Bupropion on Seizure Threshold in Depressed Patients

MDD

United States
LG Chem

Completed

BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

Healthy Male Volunteers

Korea, Republic of
Janssen Scientific Affairs, LLC

Withdrawn

An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)

Pain | Chronic Low Back Pain | Chronic Back Pain | Osteoarthritis Pain In The Hip or Knee

United States
University of California, Davis

Completed

A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine

Chronic Pain
North Dakota State University
Neuropsychiatric Research Institute, Fargo, North Dakota

Completed

A Comparison of Sustained and Extended Release Bupropion Following Bariatric Surgery

Roux en Y Gastric Bypass

United States
Pfizer

Completed

Study to Estimate the Relative Bioavailability Compared to Commercial Extended-release Tablet Formulation and the Effects of Food Or Sprinkling on Applesauce for Fesoterodine Sustained-release Beads-in-capsule Formulations in Healthy Adult Volunteers

Healthy

Belgium
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

Healthy

Korea, Republic of
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Heart Failure

Heart Failure

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Hypertension

Hypertension

China
Actavis Inc.

Completed

A Relative Bioavailability Study of Bupropion Sustained Release 150 mg Tablets Under Fasting Conditions

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Pharmacokinetics of Venlafaxine Extended-Release (ER) and Desvenlafaxine Succinate Sustained-Release (DVS SR) 50 mg in Healthy Subjects

Healthy

United States
Desitin Arzneimittel GmbH
FGK Clinical Research GmbH

Terminated

EXTENT: EXtended Tolerability and Efficacy of a Novel Formulation of Oxcarbazepine in a Trial in Partial Epilepsy

Partial Epilepsy

Germany
University of Manchester
Manchester University NHS Foundation Trust

Completed

Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery

Postoperative Pain | Wisdom Tooth

United Kingdom
Syneos Health
Asieris Pharmaceuticals (AUS) Pty Ltd.

Not yet recruiting

A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers

Healthy Volunteers
Cairo University

Not yet recruiting

Effect of Modified Lumbar Sustained Natural Apophyseal Glide on Postnatal Low Back Pain

Low Back Pain
Luye Pharma Group Ltd.

Not yet recruiting

To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets

Major Depressive Disorder
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy
Lei Lei, MD

Recruiting

Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children. (ADHD)

Attention Deficit Disorder With Hyperactivity | Executive Function Disorder

China
Lifespan
National Institute on Drug Abuse (NIDA)

Recruiting

Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews

Opioid Use Disorder | Treatment Adherence and Compliance | Criminal Justice

United States
Peking University First Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.; Beijing Biote Pharmaceutical Co.,Ltd

Recruiting

Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma

Salivary Gland Neoplasm Duct

China
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
Valenta Pharm JSC

Recruiting

Efficacy and Safety of Vespireit, Sustained-release Tablets, in Patients With Autonomic Dysfunction Syndrome Accompanied by Functional Vertigo

Vertigo | Autonomic Dysfunction

Russian Federation
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder

Schizophrenia, Schizoaffective Disorder

United States
Friends Research Institute, Inc.

Not yet recruiting

Buprenorphine for Individuals in Jail

Opioid Use Disorder

United States
Seattle Children's Hospital
Children's Hospital of Philadelphia

Not yet recruiting

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

Craniopharyngioma | Hypothalamic Obesity | Hypothalamic Tumor

United States
Cancer Research Antwerp
Bayer; Veracyte, Inc.

Recruiting

Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (THUNDER)

Prostate Cancer

Belgium
First Affiliated Hospital of Zhejiang University

Recruiting

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Venlafaxine Hydrochloride Sustained-release Tablets in Patients With Major Depression Disorder

Major Depression Disorder

China
ANRS, Emerging Infectious Diseases

Not yet recruiting

Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. (CABOPrEP)

Prevention

France
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Jiangsu Province Nanjing Brain Hospital

Recruiting

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder

Anhedonia

China
McGill University
Université de Montréal

Not yet recruiting

A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS

Amyotrophic Lateral Sclerosis

Canada
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Type 2 Diabetes (Adult Onset)

United States
Marie Badalamente

Recruiting

Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis

Carpometacarpal (CMC) Osteoarthritis

United States
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

Methamphetamine-dependence | Methamphetamine Abuse
Drug Delivery Company, LLC DBA Akyso Pharmaceuticals
National Institute on Drug Abuse (NIDA); Laboratory Corporation of America; Cognitive...

Not yet recruiting

A Phase 1, Placebo-controlled, Single-Ascending-Dose, Study of BIOPIN 6 in Healthy Adults

Opioid Use Disorder
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Abbott

Recruiting

Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia

Functional Dyspepsia

Malaysia, Armenia
Sarfez Pharmaceuticals, Inc.

Recruiting

Effect of Extended Release Torsemide in Patients With Congestive Heart Failure and Overactive Bladder

Heart Failure | Overactive Bladder | Incontinence

United States
Supernus Pharmaceuticals, Inc.

Recruiting

Open-label Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With ADHD and Mood Symptoms

Attention-Deficit/Hyperactivity Disorder

United States

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