Search clinical trials for: glucocorticoid receptor (GR) modulator (SGRM)

Total 42582 results

AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of 2-Week Treatment With Inhaled AZD7594 in Adolescents (12 to 17 Years) With Asthma

Asthma

United States
ORIC Pharmaceuticals

Terminated

Study of ORIC-101 in Combination With Anticancer Therapy

Solid Tumor

United States
GlaxoSmithKline

Completed

Clinical Evaluation of SB-497115-GR in Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Chronic Idiopathic Thrombocytopenic Purpura | Purpura, Thrombocytopenic, Idiopathic

Japan
University of Turin, Italy

Unknown

Albumin 4 gr/L vs 8 gr/L in the Prevention of Post-Paracentesis Circulatory Dysfunction

Tense Ascites in Cirrhosis

Italy
Oxford Brookes University

Completed

Salt Intake, Hydration Status and Gastrointestinal Discomfort During Fasting

Healthy

United Kingdom
Galectin Therapeutics Inc.

Completed

An Open-Label, Phase 2a Study to Evaluate Safety and Efficacy of GR-MD-02 for Treatment of Psoriasis

Psoriasis

United States
Unilever R&D
Lambda Therapeutic Research Ltd.

Completed

Dose Response Study of a Natural Extract for Reducing Post Prandial Blood Glucose

Blood Glucose

India
Chang Gung Memorial Hospital

Completed

Influence of U-relax on Vaginal Health Promotion and HPV DNA Test Change From Positive to Negative

Human Papillomavirus | Vaginal Infection

Taiwan
Grigore T. Popa University of Medicine and Pharmacy

Active, not recruiting

The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle

Cardiovascular Diseases | Fibrosis | Chronic Kidney Diseases

Romania
Glasgow Caledonian University

Completed

Effects of a Unique Co-created Intervention With Care Home Residents and University Students Following a Service-learning Methodology to Reduce Sedentary Behaviour. (GET READY)

Physical Activity | Sedentary Behaviour | Care Home Residents

United Kingdom
Changhai Hospital

Unknown

FCM Analysis GR in Steroid-Treatment Patients

Healthy
Abramson Cancer Center of the University of Pennsylvania

Terminated

Eltrombopag in Elderly Acute Myelogenous Leukemia (AML)

Acute Myelogenous Leukemia (AML)

United States
Dana-Farber Cancer Institute

Completed

Effect of Eltrombopag Plus G-CSF on Human CD34+ Cell Mobilization in Multiple Myeloma Patients Undergoing ASCT

Multiple Myeloma

United States
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
GlaxoSmithKline

Completed

Clinical Evaluation of Eltrombopag in Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic | Idiopathic Thrombocytopenic Purpura

Japan
LGD
ProRelix Services LLP

Active, not recruiting

Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients

Sickle Cell Disease

India
Weill Medical College of Cornell University
Novartis

Completed

Safety and Efficacy of Eltrombopag at Escalated Doses

Immune Thrombocytopenia | Platelet Disorder

United States
Galectin Therapeutics Inc.

Completed

Phase 1 Study to Evaluate Safety of GR-MD-02 in Subjects With Non-Alcoholic Steatohepatitis (NASH) and Advanced Fibrosis

Non-Alcoholic Steatohepatitis (NASH)

United States
Galectin Therapeutics Inc.

Completed

A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States
Laval University

Unknown

Laval University Rouge et or Post ACL Surgery Program Effectiveness

Anterior Cruciate Ligament Injuries | ACL

Canada
Cerus Corporation

Completed

A Study to Assess the Recovery and Lifespan of Radiolabeled Autologous S303 Treated Red Blood Cells (S303 RBC)

Focus: Assess Post Infusion Viability of S303 RBCs

United States
Professor Adrian Covic
Medical Sciences Academy - Romania; Victor Babes Clinical Hospital of Infectious...

Unknown

Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19 (eCardioCovid19)

Coronary Artery Disease | Hypertension | Covid-19 | Angina Pectoris | Acute Coronary Syndrome | Heart Failure, Systolic | Depression, Anxiety | Coronary Syndrome | Stent Restenosis | Angioplasty | Isolation, Social

Romania
Hvidovre University Hospital
National Research Centre for the Working Environment, Denmark; University College...

Recruiting

Optimizing Graft Selection for ACL Reconstruction (GRASE-ACL)

ACL - Anterior Cruciate Ligament Rupture

Denmark
Consorci Sanitari de l'Alt Penedès i Garraf
Centro de Salud Vilanova i la Geltrú 2 Jaume I, Barcelona, Spain; Centro de... and other collaborators

Recruiting

Neuropsychological Assessment Of The Oldest-Old Population.(NEUROPSIC-GR) (NEUROPSIC-GR)

Dementia | Cognition Disorders in Old Age

Spain
Providence Health & Services
Providence Cancer Center, Earle A. Chiles Research Institute; Galectin Therapeutics...

Completed

Galectin Inhibitor (GR-MD-02) and Ipilimumab in Patients With Metastatic Melanoma

Metastatic Melanoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Eltrombopag Olamine in Increasing Platelet Counts in Patients Undergoing Transplant

Hematopoietic Cell Transplantation Recipient | Bone Marrow Transplantation Recipient | Cord Blood Transplant Recipient

United States
Grigore T. Popa University of Medicine and Pharmacy

Unknown

Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events (iGenes-COVID19)

Covid19 | Thrombosis | Thrombophilia | Corona Virus Infection | ARDS | Thromboses, Intracranial | Thromboses, Deep Vein | RAAS

Romania
Centre Medicina Esportiva i Osteopatia, Spain

Completed

Systemic Adverse Effects After Osteopathic Treatment and Vitamin C

Oxidative Stress | Adverse Effects | Ascorbic Acid

Spain
Bioblast Pharma Ltd.

Completed

Continuation Protocol to Protocol BBCO-001 (HOPEMD)

Muscular Dystrophy, Oculopharyngeal (OPMD)

Canada
Imperial College London
AstraZeneca

Completed

Effect of Symbicort on GR Localisation in Asthma

Asthma

United Kingdom
Cerus Corporation

Completed

Study to Assess S303 RBCs and Evaluate Safety and Efficacy in Patients Requiring Transfusion Support of Acute Anemia

Focus:Use of S303 RBCs in Patients With Acute Anemia

Germany
Ankara City Hospital Bilkent

Recruiting

Comparison of the Detection Rates of 50 Gr-100 gr OGTT and 75 gr OGTT That Require Medical Treatment of GDM

Gestational Diabetes | Glucose Intolerance During Pregnancy

Turkey
Cerus Corporation

Completed

Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion

Thalassemia Major

Turkey, Italy
Amsterdam UMC, location VUmc
Corcept Therapeutics; Netherlands Brain Foundation

Recruiting

RESET-medication Glucocorticoid Receptor (GR) Blockade as Disease Modifying Treatment for Depression With Childhood Trauma (RESET-m)

Major Depressive Disorder | Childhood Trauma

Netherlands
Cairo University

Not yet recruiting

Effect of Gradually Increasing Force Magnitude on the Rate of Canine Retraction Randomized Controlled Trial

Canine Retraction

Egypt
GlaxoSmithKline

Completed

Japanese Phase II Study of SB-497115-GR in Hepatitis C Virus Infected Patients

Hepatitis C, Chronic

Japan
University of Pittsburgh

Completed

L-Citrulline Supplementation Pilot Study for Overweight Late Onset Asthmatics (SANDIA)

Asthma

United States
Rabin Medical Center

Unknown

Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial (EFOPaKR-01)

Rheumatoid Arthritis

Israel
Pulmatrix Inc.

Completed

A Phase 1b Study of PUR1800 in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Copenhagen University Hospital at Herlev
Rigshospitalet, Denmark

Terminated

Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

Infertility | Varicocele | Semen Quality

Denmark
CHU de Reims

Unknown

Mutations of Glucocorticoid Receptor in Bilateral Adrenal Hyperplasia (MUTA-GR)

General Glucocorticoid Resistance

France
Westat
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (RBC-IMPACT)

Sickle Cell Disease | Thalassemia | Pediatric Cancer

United States, Brazil
Imperial College London
AstraZeneca

Withdrawn

GR Defect in Sputum Cells in COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Emory University

Terminated

Physiologic Effects of RBC Transfusion

Red Blood Cell Transfusion

United States
Aristotle University Of Thessaloniki

Not yet recruiting

Factors Influencing Cardiovascular Prognosis (Pythia-GR)

Cardiovascular Mortality
Corcept Therapeutics

Active, not recruiting

Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Ovarian Cancer

United States, Belgium, Canada, Italy, Spain
Imperial College London
AstraZeneca

Completed

Effect of Symbicort ® on GR in Sputum in COPD

Chronic Obstructive Lung Disease

United Kingdom
Corcept Therapeutics

Terminated

Study of Relacorilant in Combination With Nab-Paclitaxel in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (RELIANT)

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Tilburg University

Completed

Non-surgical Treatment of Carpal Tunnel Syndrome by Means of Mechanical Traction (MT-CTS)

Carpal Tunnel Syndrome

Netherlands
University of Applied Sciences and Arts of Southern...

Completed

Clinical Study to Assess the Effectiveness of the Device Patello (Patello)

Passiv Continuous Patella Mobilisation

Switzerland

Search clinical trials for: glucocorticoid receptor (GR) modulator (SGRM)

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