Search clinical trials for: hepatic de novo lipogenesis

Total 486595 results

Columbia University
University of California, Berkeley

Recruiting

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin Resistance | Prediabetic State | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

United States
Maastricht University Medical Center

Recruiting

Effect of Dietary SFA and Fructose on Hepatic Insulin Sensitivity

Insulin Resistance

Netherlands
University of Colorado, Denver

Completed

Post-Prandial Liver Glucose Metabolism in PCOS (PLUM)

Obesity | Polycystic Ovarian Syndrome | Hepatic Steatosis

United States
The Rogosin Institute
University of Missouri-Columbia; Weill Medical College of Cornell University

Terminated

Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity

Adolescent Obesity

United States
University of California, Davis
Touro University, California

Completed

Orange Juice And Sugar Intervention Study (OASIS)

Metabolic Syndrome | Cardiovascular Risk Factor | Insulin Sensitivity | Type2 Diabetes Mellitus

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); American...

Completed

Hepatic De Novo Lipogenesis (DNL)in the Pathogenesis of Hepatic Steatosis in Obese Youth (DNL)

Fatty Liver | Hepatic Steatosis

United States
University of Colorado, Denver

Completed

Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS (ORANGE)

Obesity | Polycystic Ovarian Syndrome | Hepatic Steatosis

United States
University of Lausanne
University of Bern

Completed

Effects of an Amino-acid Supplement on Hepatic Lipid Metabolism (AMINOFRUCT)

Metabolic Syndrome

Switzerland
University of Lausanne

Completed

Acute Effect of Fructose on Lipid Metabolism and Gender Differences

Lipid Metabolism

Switzerland
University of Lausanne
University Hospital Inselspital, Berne

Completed

Effects of Dietary Proteins on Hepatic Lipid Metabolism

Metabolic Syndrome X

Switzerland
University of Lausanne
Centre Hospitalier Universitaire Vaudois

Completed

Effects of Fructose and Exercise on Hepatic Lipid Metabolism (FRUCTEXER)

Metabolism

Switzerland
University of Utah

Completed

Study of Hepatic Glucose Production and De Novo Lipogenesis in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
Seoul National University Hospital

Recruiting

Clinical Effectiveness of Microwave Ablation Using Starwave Microwave Generator for Hepatic Malignancies

Liver Malignant Tumors

Korea, Republic of
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
Shanghai Zhongshan Hospital

Not yet recruiting

PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7

Hepatocellular Carcinoma
Chen Xiaoping

Not yet recruiting

Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model

HCC
Medical University of Vienna

Recruiting

Vienna Hypothermic Oxygenated Machine Perfusion Study (VIHOMPS)

End Stage Liver Disease | Hepatocellular Carcinoma

Austria
Shanghai Changzheng Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

Advanced Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and...

Recruiting

Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure

HCC

China
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer

Liver Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation

Liver Cancer | Liver Transplant

China
Hunan Cancer Hospital

Recruiting

Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Guangxi Medical University

Recruiting

Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Prospective, Single-arm, Multicenter Phase II Clinical Study of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Adebrelimab

China
Twinpig Biolab, Inc.

Not yet recruiting

Clinical Trial of TB511 in Advanced Solid Tumors

Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Prostate Cancer
Hospital Universitari Vall d'Hebron Research Institute

Recruiting

The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.

Liver Tumor; Surgery

Spain
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

DEB-TACE+RALOX-HAIC vs DEB-TACE for Large HCC

Hepatocellular Carcinoma Non-resectable

China
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCC

Hepatocellular Carcinoma Non-resectable

China
Gene Solutions
University of Medicine and Pharmacy at Ho Chi Minh City

Recruiting

Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE) (K-ACCELERATE)

Cancer, Breast | Cancer, Lung | Cancer Colon | Cancer, Gastric | Cancer, Liver

Vietnam
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis

Hepatocellular Carcinoma | Radiotherapy | Pembrolizumab | Tumor Thrombosis

China
Harbin Medical University

Not yet recruiting

HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer

Biliary Tract Cancer
Wuhan Union Hospital, China

Recruiting

Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma

Malignant Neoplasm of Liver

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Evaluating the Role of ChatGPT in Educating Patients With Early-stage Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Taiwan
Tianjin Medical University Cancer Institute and...

Recruiting

Safety and Efficacy of XELOX Combined With Sintilimab and Lenvatinib in Advanced AFP-positive Gastric Cancer Patients

Gastric Cancer

China
Shanghai Zhongshan Hospital

Not yet recruiting

Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy

Hepatocellular Carcinoma

China
Chang Gung Memorial Hospital

Not yet recruiting

Evaluation of Immune Responses and Outcomes in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy

Hepatocellular Carcinoma

Taiwan
Tianjin Medical University Cancer Institute and...

Recruiting

Ivonescimab Combined With HAIC for the Treatment of Unresectable Hepatocellular Carcinoma（uHCC）.

Hepatocellular Carcinoma | Hepatocellular Carcinoma Non-resectable

China
Yehua Shen

Not yet recruiting

HAIC Combined With PD-L1 Plus Regorafenib in the Treatment of Advanced Hepatocellular Carcinoma After Immunotherapy Failure

HCC - Hepatocellular Carcinoma
Lee's Pharmaceutical Limited

Recruiting

Study of AU409 Capsule in Advanced Hepatocellular Carcinoma Patients Who Failed Standard Treatment

Advanced Hepatocellular Carcinoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Serplulimab Combined With Bevacizumab Biosimilar and HAIC in Advanced Hepatocellular Carcinoma (HCC) Patients

Advanced Hepatocellular Carcinoma

China
Akeso

Not yet recruiting

A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Shandong Cancer Hospital and Institute

Recruiting

First-line Treatment for Unresectable Locally Advanced Distal Cholangiocarcinoma Combining Radiotherapy and HAIC

Intrahepatic Cholangiocarcinoma

China
Qianfoshan Hospital

Recruiting

Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular

China
Beijing 302 Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.; Chinese Academy of...

Not yet recruiting

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial for First-line Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma
Gustave Roussy, Cancer Campus, Grand Paris
Medical University of Vienna; University Hospital, Essen; Fondazione IRCCS Istituto... and other collaborators

Recruiting

CARE1 Pragmatic Clinical Trial (CARE1)

Metastatic Kidney Carcinoma | Metastatic Kidney Cancer

France
Beijing 302 Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.; Chinese Academy of...

Not yet recruiting

Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody

Hepatocellular Carcinoma
University Health Network, Toronto

Not yet recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (ULTRAS)

Liver Metastases
Sulai Liu

Recruiting

HAIC Combined With Durvalumab and Tremelimumab and Lenvatinib in uHCC

Hepatocellular Carcinoma

China
7 Hills Pharma, LLC

Not yet recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States

Search clinical trials for: hepatic de novo lipogenesis

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