Search clinical trials for: hepatic function disorder

Total 166390 results

Zhujiang Hospital

Recruiting

Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD (HHTN)

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus

China
Medical University of Vienna

Recruiting

Effects of Cross-sex Hormone Treatment on Cardiac Function, Myocardial and Hepatic Fat Content

Gender Dysphoria

Austria
Sohag University

Not yet recruiting

Prevelance Of Cutaneous Disorders Among Patients With Heamatologic Malignancies

Dermatologic Disorders With Heamatologic Malignancies Patients

Egypt
Laval University

Recruiting

Diet Impact on Hepatic Transcriptomics and Lipidomics in Pre-diabetes (DGENE-NAFLD)

Pre-diabetes

Canada
Daewoong Pharmaceutical Co. LTD.

Recruiting

To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function

Diabetes Mellitus, Type 2

Korea, Republic of
Postgraduate Institute of Medical Education and...

Recruiting

Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome (Liv-Thrombus)

Portal Vein Thrombosis | Anticoagulants and Bleeding Disorders | Hepatic Vein Thromboses | Hepatic Venous Outflow Obstruction | Portal Hypertension, Noncirrhotic | Portal Vein Occlusion | Portal Vein Embolism | JAK2 Mutation | CALR Gene Mutation | Prothrombin G20210A

India
GlaxoSmithKline

Recruiting

A Study of Belantamab Mafodotin in Multiple Myeloma Participants With Normal and Impaired Hepatic Function (DREAMM 13)

Multiple Myeloma

Greece, Korea, Republic of, United States
Chinese University of Hong Kong

Recruiting

Safety and Efficacy of Fecal Microbiota Transplantation

Alcohol Dependence | Multiple Sclerosis | Obesity | Diabetes Mellitus | Hepatic Encephalopathy | Irritable Bowel Syndrome | Constipation | Celiac Disease | Crohn Disease | Ulcerative Colitis | Liver Disease | Idiopathic Thrombocytopenic Purpura | Clostridium Difficile Infection | Alopecia | Autism | Multiple Organ Dysfunction... and other conditions

Hong Kong
University of Colorado, Denver

Active, not recruiting

Hepatic Mitochondrial Function in Youth (MANGO)

Obesity | Bariatric Surgery Candidate | Adolescent Obesity | Hepatic Steatosis

United States
Postgraduate Institute of Medical Education and...

Completed

Effects of Direct-acting Antiviral Agents on HCV Cognitive Function, and Depression in HCV Related Cirrhosis: A Prospective Clinical Trial

Depression in Chronic Hepatitis C

India
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
Huiwu Xing

Completed

Prediction of Early Recovery of Liver Function After LDLT in Children: An Ambispective Cohort Study

Liver and Biliary Tract Disorders in Duration of Pregnancy | Other End-stage Liver Diseases in Children

China
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Adrenergic System in Islet Transplantation

Hypoglycemia | Type1diabetes | Islet Cell Transplantation | Hypoglycemia Unawareness

United States
Bayer

Completed

A Study to Learn How the Study Treatment Asundexian Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body in Participants With Mild or Moderate Reduction of Liver Function Compared to Participants With Normal Liver Function

Atrial Fibrillation | Hepatic Impairment | Acute Myocardial Infarction | Prevention of Thromboembolic Events | Non-cardioembolic Ischemic Stroke

Germany
University of Aarhus
Aarhus University Hospital

Completed

sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis

Wilsons Disease

Denmark
National Institute of Neurological Disorders and...

Completed

Study of Hepatic Function in Patients With Spinal and Bulbar Muscular Atrophy

Motor Neuron Disease | Spinal and Bulbar Muscular Atrophy (SBMA)

United States
Celgene

Completed

A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg

Multiple Myeloma

United States, Japan
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Terminated

Mitochondrial Function in Patients With Severe Liver Disease (SLDglyc)

Hepatic Insufficiency | Hypoalbuminemia

United States
Vigonvita Life Sciences
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Completed

Study of the Pharmacokinetics and Safety of TPN171H Tablets in Subjects With Mild ,Moderate Hepatic Insufficiency and Normal Liver Function

Erectile Dysfunction | Pulmonary Arterial Hypertension

China
F Javier Belda

Withdrawn

Sevoflurane- Safety in Long-term Sedation Procedures

Renal Function | Fluoride Poisoning | Hepatic Function | Poisoning by Inhaled Anaesthetic | Recovery From Sedation

Spain
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
Memorial Hospital Groups

Completed

The Early Strength Training Program in Post-transplant Liver Cases

Quality of Life | Fatigue | Muscle Weakness | Sarcopenia | Chronic Liver Failure | Liver Transplant Disorder | Muscle Loss | End Stage Liver DIsease

Turkey
Chuncheon Sacred Heart Hospital

Completed

Cognitive Function of Alcoholic Compensated Liver Cirrhosis

Alcoholic Liver Disease

Korea, Republic of
Hospital General Universitario Gregorio Marañon

Completed

Major Liver Resection: Early Clotting Disorders and Functional Impairment.

Hepatic Insufficiency | Blood Coagulation Disorders

Spain
Albert Einstein Healthcare Network

Completed

Monitoring of Symptoms and Cognitive Function Using Telehealth

End Stage Liver Disease

United States
The University of Texas Health Science Center at...
Janssen Scientific Affairs, LLC

Completed

Effect of Combined Incretin-Based Therapy Plus Canagliflozin on Glycemic Control and the Compensatory Rise in Hepatic Glucose Production in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
Augusta University
Yale University; University of Alabama at Birmingham; Tufts University

Unknown

Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study)

Obesity | Insulin Resistance | Insulin Sensitivity | Prediabetes | Beta-Cell Dysfunction

United States
Zagazig University

Unknown

Coenzyme Q10 and Meclofenoxate in Hepatic Encephalopathy (EH)

Hepatic Encephalopathy | Coenzyme Q10 | Intellectual Functioning Disability

Egypt
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Aga Khan University

Unknown

Intermittent Fasting in Dyslipidemia

Kidney Diseases | Anemia | Dyslipidemias | Cardiac Function | Intermittent Fasting | HDL Cholesterol, Low Serum | Hepatic Enzymes and Function Abnormalities

Pakistan
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics of Alisertib in Adults With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Function

Advanced Solid Tumors | Relapsed/Refractory Lymphoma

United States
University of Lausanne Hospitals

Completed

Indocyanine Green and Portal Pressure in Viral and Alcoholic Cirrhotic Patients With Hepatocarcinoma

Carcinoma, Hepatocellular | Alcoholic Cirrhosis | Viral Cirrhosis | Postoperative Hepatic Failure

Switzerland
Nhat Nhat Pharmaceutical Company

Unknown

TONKA Versus Legalon for Lowering Hepatic Enzymes in Liver Function Disorder Patients.

Liver Function Failure

Vietnam
Eli Lilly and Company

Completed

A Study of LY2216684 in Participants With Impaired Hepatic Function

Depressive Disorder, Major

United States
Medical University of Warsaw

Completed

Liver Function After Intravenous Methylprednisolone Administration

Liver Diseases | Liver Failure | Graves Ophthalmopathy | Graves Disease | Acute Liver Failure | Acute Liver Injury | Liver Dysfunction | Glucocorticoids Toxicity | Liver Injury | Liver Insufficiency | Acute Liver Injury, Drug Induced | Methylprednisolone Adverse Reaction | Dysthyroid Orbitopathy | Dysthyroid Ophthalmopathy
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of MK-3102 in Participants With Impaired Hepatic Function (MK-3102-031)

Diabetes Mellitus, Type 2
University Hospital, Geneva

Unknown

APAP Hepatotoxicity After Therapeutic Doses

Malnutrition | Paracetamol Toxicity | Hepatotoxicity

Switzerland
Novo Nordisk A/S

Completed

Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Diabetes Mellitus, Type 2 | Diabetes | Hepatic Impaired

Poland, Slovakia
Zhihong LU

Completed

Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum (TRIP)

Renal Function Disorder | Hepatic Dysfunction Transient

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired Subjects

Schizophrenia

United States
Medical University of Vienna

Unknown

Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis

Erectile Dysfunction | Cirrhosis

Austria
University of Liverpool
Imperial College London; Royal Liverpool University Hospital; University of Surrey and other collaborators

Unknown

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

Non Alcoholic Fatty Liver Disease

United Kingdom
Hunter Holmes Mcguire Veteran Affairs Medical Center
Otsuka America Pharmaceutical

Completed

Effect of Tolvaptan on Cognitive Function in Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Hyponatremia

United States
Repros Therapeutics Inc.

Completed

Evaluation of the Pharmacokinetics and Safety of Androxal in Male Subjects With Impaired Hepatic Function

Secondary Hypogonadism

United States
National Cancer Institute (NCI)

Completed

Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function

Lymphoma | Unspecified Adult Solid Tumor, Protocol Specific | Hepatic Complications

United States
Kennon Heard
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days (Non-Drinker)

Drug Induced Liver Injury

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver Function

Schizophrenia | Hepatic Impairment
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Hepatic Function in Alcoholics Following 5 Days of Acetaminophen Dosing

Alcohol Related Disorders

United States, Canada
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Hepatic Function During and Following Three Days of Acetaminophen Dosing in Alcoholics

Alcohol Related Disorders

United States
University of Bonn

Recruiting

Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic (GCAIO)

Giant Cell Arteritis | Polymyalgia Rheumatica

Germany

Search clinical trials for: hepatic function disorder

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