Search clinical trials for: immediate release tacrolimus

Total 13685 results

University of British Columbia
Paladin Labs Inc.

Recruiting

Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations (LCP-TAC)

Liver Transplantation | Neurotoxicity | Tremor | Tacrolimus | Immunosuppression

Canada
Heleen Grootjans
Chiesi Farmaceutici S.p.A.

Recruiting

Trial Comparing Immediate Versus Extended Release Tacrolimus; Reducing Calcineurin Inhibitor Related Toxicity in Lung Transplantation Patients (REVOLUTION)

Lung Transplant; Complications

Netherlands
Loyola University
Veloxis Pharmaceuticals

Recruiting

Renal Tubular Injury and Transplant Outcomes in Cardiac Recipients Converting From IR Tacrolimus to XR Tacrolimus

Chronic Kidney Diseases | Heart Transplant

United States
Roy D. Bloom, MD
Veloxis Pharmaceuticals

Recruiting

Pulse Wave Velocity, Tacrolimus Time in Therapeutic Range and CV in African American Kidney Transplants (PTAAK)

Kidney Transplant; Complications

United States
Imperial College London

Recruiting

Extended Release Versus Immediate Release Tacrolimus Following Renal Allograft Failure to Reduce Allosensitisation (EVITRA)

Immunosuppression | Kidney Transplant Failure | Allosensitization

United Kingdom
Yale University
Veloxis Pharmaceuticals

Recruiting

Assessment of Cognitive Function Before and After Conversion From Immediate Release Tacrolimus to Envarsus XR.

Kidney Transplant; Complications

United States
Medical University of South Carolina
Veloxis Pharmaceuticals

Completed

Envarsus Neurotoxicity Burden in Liver Transplant Patients

Neurotoxicity | Liver Transplant; Complications

United States
Sentara Norfolk General Hospital
Veloxis Pharmaceuticals

Completed

Evaluation Dose Adjustments in Kidney Transplant Patients on Immediate Release and Extended Release Tacrolimus (EVOKE-RT)

Transplant;Failure,Kidney

United States
NYU Langone Health

Completed

Envarsus XR in Lung Transplant

Lung Transplant

United States
Astellas Pharma China, Inc.

Completed

Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients

Kidney Transplant

China
Mayo Clinic
Veloxis Pharmaceuticals

Active, not recruiting

Envarsus XR Compared to Immediate Release Tacrolimus (SIMPLE)

Kidney Transplant Recipients

United States
Cedars-Sinai Medical Center
Veloxis Pharmaceuticals

Active, not recruiting

Comparison of Tacrolimus Extended-Release (Envarsus XR) to Tacrolimus Immediate-Release in HLA Sensitized Kidney Transplant Recipients

Kidney Transplant Rejection

United States
University of California, Los Angeles
Veloxis Pharmaceuticals

Active, not recruiting

Envarsus XR® in Adolescent Renal Transplant Recipients (EnvarsusXR)

Kidney Transplantation | Renal Transplantation | Grafting, Kidney

United States
University of Kansas Medical Center
Veloxis Pharmaceuticals

Completed

Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Immediate Release Tacrolimus to Slow Release Envarsus

End Stage Renal Disease

United States
University of Minnesota

Completed

Comparison of the Cognitive and Motor Effects of Treatment Between an Immediate- and Extended-release Tacrolimus (Envarsus® XR) Based Immunosuppression Regimen in Kidney Transplant Recipients

Kidney Transplant Failure and Rejection

United States
Astellas Pharma Global Development, Inc.

Completed

To Compare the Effects of Immediate-release Tacrolimus and Astagraf XL on Donor-Specific Antibody (DSA) Formation and the Development of Immune Activation (IA) in de Novo Kidney Transplant Recipients (ASTOUND)

Kidney Transplantation

United States
University Hospital, Limoges

Unknown

PK Assessment of Tacrolimus Exposure Before and After a Switch From Twice Daily Immediate-release (Prograf®) to Once-daily Prolonged Release Tacrolimus (Envarsus®) (ENVARSWITCH)

Allograft

France
UMC Utrecht

Completed

Extended Release Tacrolimus (Advagraf®) in Severe Adult Atopic Dermatitis Patients

Atopic Dermatitis

Netherlands
Astellas Pharma Canada, Inc.

Completed

A Comparison of the Effects of Extended Release Tacrolimus (Advagraf®) vs. Immediate Release Tacrolimus (Prograf®) on Kidney Function in Healthy Male Volunteers

Healthy

Canada
Syneos Health
Asieris Pharmaceuticals (AUS) Pty Ltd.

Not yet recruiting

A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers

Healthy Volunteers
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Ascentage Pharma Group Inc.

Recruiting

A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.

CLL/SLL

China
Bayer

Recruiting

A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants

Healthy Volunteers | Heartburn | Indigestion | Stomach Acid Related Symptoms | Nocturnal Stomach Acid Related Symptoms

United Kingdom
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Edward Geissler
Chiesi Pharmaceuticals GmbH

Recruiting

Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs (TaC:Drop)

Immunosuppression

Germany
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
Sarfez Pharmaceuticals, Inc.

Recruiting

Effect of Extended Release Torsemide in Patients With Congestive Heart Failure and Overactive Bladder

Heart Failure | Overactive Bladder | Incontinence

United States
RenJi Hospital

Not yet recruiting

Prospective, Multicenter Clinical Study of Prolonged-release Tacrolimus in Stable Pediatric Liver Transplant Recipients

Liver Transplant

China
Sarfez Pharmaceuticals, Inc.
Sarfez Pharmaceuticals, Inc.

Recruiting

Immediate Release Versus Extended Release Torsemide After Salty Meal

Heart Failure

United States
Yonsei University

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Suvaro®OD Tablet in Patients With Dyslipidemia

Dyslipidemia

Korea, Republic of
Beijing Tsinghua Chang Gung Hospital

Not yet recruiting

Early Conversion of Prolonged-release Tacrolimus in Liver Transplantation.

Liver Transplantation
Merck Sharp & Dohme LLC

Recruiting

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Israel, Taiwan, United Kingdom, Chile, Canada, Japan, Brazil, China
AbbVie

Not yet recruiting

A Study to Assess the Relative Bioavailability of Three Immediate-Release Tablet Formulations of ABBV-903 in Healthy Adult Volunteers

Healthy Volunteers
University Hospital, Essen

Recruiting

Pharmacokinetics, Effectiveness and Tolerability of Prolonged-release Tacrolimus After Paediatric Kidney Transplantation (Pro-Tac)

Pediatric Kidney Disease

Germany
Rachel G. Greenberg, MD, MB, MHS
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS) (HYP01)

Hyperactivity in Children With Down Syndrome | Impulsivity in Children With Down Syndrome

United States
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
Nimble Science Ltd.
MRM Health N.V.

Recruiting

Observational Small Intestine and Blood Fingerprint (SmIle) Study in Parkinson's Disease (SmIle)

Parkinson Disease

Canada
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

Pain | Analgesia | Abuse Opioids

United States
Cerevel Therapeutics, LLC

Recruiting

A Study Evaluating the Pharmacokinetics and Relative Bioavailability of Emraclidine Immediate-Release Tablets in Healthy Adult Participants

Healthy Participants

United States
University Hospital, Strasbourg, France

Recruiting

EEG-MRI Imaging of Methylphenidate Effects in Adult ADHD and Attentional Symptoms in Mood Disorders (ImAteM-TDA)

Adult ADHD | Adult-onset ADHD With Mood Disorder

France
Yeditepe University

Not yet recruiting

Comparison of the Immediate Effects of Physiotherapist and Self-administered Myofascial Release Techniques on Flexibility and Jumping Ability in Basketball Players

Myofascial Spasm

Turkey
Alexion

Recruiting

A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants

Healthy Participants

United Kingdom
Terran Biosciences Australia Pty Ltd

Recruiting

A Study of Idazoxan in Healthy Participants

Healthy

Australia
Vastra Gotaland Region
Sahlgrenska University Hospital, Sweden; The Gothenburg Society of Medicine; Åke... and other collaborators

Not yet recruiting

Treatment Study in Patients Treated With Both Insulin & Hydrocortisone (INSCORT)

Diabetes Mellitus | Adrenal Insufficiency | Polyglandular Autoimmune Syndrome

Sweden
Ankara Yildirim Beyazıt University

Recruiting

Immediate Effects of Hamstring Stretching Alone or Combined With Myofascial Release

Temporomandibular Joint Disorders | Hamstring Injury | Masseter | Myofascial Release | Stretching | Surface EMG

Turkey
Royal Victoria Hospital, Canada

Not yet recruiting

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder (STOPIT)

Moderate to Severe Opioid Use Disorder

Canada
Cairo University

Not yet recruiting

Effect of Botox Injection in Anterior Belly of Digastric on Skeletal Relapse Following Mandibular Advancement Surgery

Orthognathic Relapse
Bellus Health Inc. - a GSK company

Recruiting

Assessment of the Pharmacokinetics of BLU-5937 Extended Release Prototypes and a BLU-5937 Immediate Release Reference Formulation

Healthy | Cough

United Kingdom
University of Alberta

Recruiting

Extended-Release Tacrolimus Following Liver Transplantation

Cardiovascular Diseases | Renal Insufficiency | Metabolic Syndrome | Liver Transplant; Complications | Immunosuppressant Adverse Reaction

Canada
Erasmus Medical Center
Ludwig Institute for Cancer Research; Dutch Cancer Society; Stichting Coolsingel... and other collaborators

Recruiting

MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck Cancer (MC2TCR)

Melanoma | Head and Neck Cancer | Melanoma, Uveal

Netherlands

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