Search clinical trials for: immune-mediated systemic disease

Total 383423 results

Novartis Pharmaceuticals

Completed

Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis

Moderate to Severe Chronic Plaque-type Psoriasis

Belgium, Spain, Russian Federation, Germany, United States, Czechia, Peru, Poland, Estonia
Novartis Pharmaceuticals

Completed

Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome (METABOLYX)

Psoriasis | Metabolic Syndrome

Germany
Novartis Pharmaceuticals

Completed

Efficacy and Safety of 2 Secukinumab Regimens in 90kg or More Weight Group With Moderate/Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque-type Psoriasis

United States, Hungary, Italy, Russian Federation, Germany, Czechia, Canada
Novartis Pharmaceuticals

Completed

Comparison of Secukinumab Versus Guselkumab in Clearing Psoriatic Plaques Refractory to Ustekinumab (ARROW)

Chronic Plaque-type Psoriasis

Germany, United States, Canada
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in Chinese Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

China
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

Plaque Psoriasis

China, Thailand, Philippines, Turkey, Hungary, Malaysia
Novartis Pharmaceuticals

Completed

A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis. (PROSE)

Plaque Psoriasis

Germany, United Kingdom, Belgium, Czechia, Estonia, Italy, France, Israel, Spain, Bulgaria, Lithuania, Portugal, Poland, Romania, Latvia, Greece, Slovakia
Novartis Pharmaceuticals

Completed

Secukinumab Dosage Optimisation in Partial Responders With Moderate to Severe Plaque-type Psoriasis (GAIN)

Moderate to Severe Plaque-type Psoriasis

Germany
Novartis Pharmaceuticals

Completed

Study to Evaluate Psoriasis Severity and Its Psychosocial Impact Using the Simplified Psoriasis Index (SPI), as Well as Long-term Safety, Tolerability and Efficacy of Secukinumab Administered Subcutaneously in Patients With Moderate to Severe Psoriasis (IPSI-PSO)

Psoriasis

France
Novartis Pharmaceuticals

Completed

Judging the Efficacy of Secukinumab in Patients With Psoriasis Using AutoiNjector: a Clinical Trial Evaluating Treatment Results (JUNCTURE) (JUNCTURE)

Plaque-type Psoriasis

Germany, United States, France, Estonia, Canada
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

Systemic Sclerosis | Autoimmune Disorders

United States
Hospices Civils de Lyon

Not yet recruiting

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases (GENIALII)

Autoimmune Diseases | Genetic Disease | Autoinflammatory Disease | Systemic Lupus

France
Hospices Civils de Lyon

Not yet recruiting

Recurrent Campylobacter Bacteraemia in Immunocompromised Patients (CABARET)

Campylobacter Infections

France
Atara Biotherapeutics

Not yet recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Lupus Nephritis

Systemic Lupus Erythematosus | Lupus Nephritis
Tufts University

Not yet recruiting

Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planus

Oral Lichen Planus | Oral Lichenoid Reaction

United States
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases (BAH247)

Autoimmune Diseases | Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Lupus Erythematosus Acute

China
Assiut University

Not yet recruiting

T Regulatory Cells IN LUPUS NEPHRITIS

Lupus Nephritis
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM

Gastric Cancer, Metastatic
Fondation Hôpital Saint-Joseph

Not yet recruiting

Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients With Enterobacterales Bacteremia (MHR-Blood)

Bacteremia
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Not yet recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Bacteremia | Endocarditis

Spain
Bristol-Myers Squibb

Recruiting

Observational Study in Japanese Patients With Peripheral T-Cell Lymphoma Who Received Second-Line Therapy

Peripheral T-cell Lymphoma

Japan
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy
Peking Union Medical College Hospital
Central South University; Zhejiang University; Beijing Children's Hospital; Shenzhen... and other collaborators

Recruiting

Observational Study of Pediatric Rheumatic and Immunologic Diseases in China: The CAPRID Registry

Autoimmune Diseases | Autoinflammatory Diseases

China
Liangjing Lu
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relmacabtagene Autoleucel for the Treatment of Systemic Sclerosis

Systemic Sclerosis

China
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Not yet recruiting

Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Immune Thrombocytopenia | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Primary Biliary Cholangitis
Indonesia University

Not yet recruiting

Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies

Sepsis, Neonatal
IRCCS San Raffaele

Recruiting

INfectious DIsease REgistry BIObank (INDI-REBIO)

Central Nervous System Infections | Infective Endocarditis | Vertebral Osteomyelitis | Bone and Joint Infections | Bloodstream Infections | Endovascular Infections | CIED-related Infections

Italy
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Patients With Systemic Sclerosis Without Specific or Associated Autoantibodies (SCLERONAB)

Systemic Sclerosis

France
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Pharmacological Effect of a Single Intravenous Infusion of Belantamab in Male and Female Participants Aged 18 to 75 With Moderate to Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
GlaxoSmithKline

Not yet recruiting

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) (BE-EARLY)

Systemic Lupus Erythematosus
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands
St George's, University of London
MU-JHU CARE; Biomedical Research and Training Institute, Zimbabwe

Recruiting

Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe (NeoRisk)

Neonatal Sepsis

Uganda, United Kingdom
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Lupus Nephritis

China
University of Bologna

Not yet recruiting

Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels

Inflammation | Hypercholesterolemia

Italy
Sohag University

Not yet recruiting

The Predictive and Prognostic Values of the Fibrinogen to Albumin Ratio and C-reactive Protien to Albumin Ratio in Systemic Lupus Erythematosus Patients

Systemic Lupus Erythematosus
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Wuhan Union Hospital, China
ITabMed Co., Ltd.

Not yet recruiting

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
RenJi Hospital

Not yet recruiting

Efficacy and Safety of Telitacicept for Prevention of Flares in SLE Patients

Systemic Lupus Erythematosus
Ciusss de L'Est de l'Île de Montréal

Recruiting

Donor-Derived EBV-Specific T Cells for Life Threatening EBV-lymphoma (OLIP-EBV-TCL-01-HMR01)

EBV Associated Lymphoma

Canada
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Not yet recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Prostate Cancer

United States
Novartis Pharmaceuticals

Not yet recruiting

Iptacopan in Patients With ANCA Associated Vasculitis

Anti-Neutrophil Cytoplasm Antibodies (ANCA) Associated Vasculitis
University of Mississippi Medical Center
University of Alabama at Birmingham

Recruiting

Low Systemic/High Local Exercise Load in Peds SCD

Sickle Cell Anemia in Children

United States
Universidad Católica San Antonio de Murcia

Recruiting

Myofascial Techniques and Proprioceptive Neuromuscular Facilitation in Patients With Systemic Lupus Erythematosus.

System; Lupus Erythematosus

Spain
The Methodist Hospital Research Institute

Recruiting

Systemic and Central Inflammation in AD

Alzheimer Disease

United States
Chunling Jiang

Not yet recruiting

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Necrotizing Pancreatitis

Search clinical trials for: immune-mediated systemic disease

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