Search clinical trials for: immunocytokine

Total 16 results

SOTIO Biotech AG

Recruiting

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Advanced Solid Tumor | Metastatic Solid Tumor

United States, Spain, Czechia, Belgium, France
GI Innovation, Inc.

Recruiting

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor

Korea, Republic of, United States
National Cancer Institute (NCI)

Recruiting

T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Cancer Of Prostate

United States
National Cancer Institute (NCI)

Recruiting

NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Kaposi Sarcoma

United States
National Cancer Institute (NCI)

Recruiting

Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Urogenital Neoplasms | Bladder Cancer | Urothelial Cancer | Genitourinary Cancer | Urogenital Cancer

United States
University of Wisconsin, Madison
Bristol-Myers Squibb; National Cancer Institute (NCI); AnYxis Immuno-Oncology... and other collaborators

Suspended

IT-hu14.18-IL2 With Radiation, Nivolumab and Ipilimumab for Melanoma

Melanoma

United States
M.D. Anderson Cancer Center

Withdrawn

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Hormone Receptor Positive Breast Adenocarcinoma | Metastatic HER2 Negative Breast Adenocarcinoma

United States
University of Wisconsin, Madison
National Cancer Institute (NCI); Solving Kids' Cancer; Wade's Army; Midwest Athletes... and other collaborators

Withdrawn

Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2

Osteosarcoma | Neuroblastoma | Recurrent Neuroblastoma | Relapsed Neuroblastoma

United States
National Cancer Institute (NCI)

Terminated

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Metastatic Pancreatic Cancer | Histologically or Cytologically Confirmed Pancreatic Cancer | Unresectable or Borderline Resectable Pancreatic Cancer

United States
National Cancer Institute (NCI)

Terminated

A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinoma

Urothelial Cancer

United States
Alopexx Oncology, LLC

Terminated

Open-Label Extension Study of De-immunized DI-Leu16-IL2 Immunocytokine Administered in Participants With B-cell NHL

B-cell Non-Hodgkin Lymphoma

United States
Alopexx Oncology, LLC

Terminated

A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL (DI-Leu16-IL2)

B-cell Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Fusion Protein Cytokine Therapy After Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Neuroblastoma

United States, Canada
Merck KGaA, Darmstadt, Germany

Completed

EMD 521873 in Advanced Solid Tumors, MTD Finding

Non-Hodgkin Lymphoma

Germany, Switzerland
Merck KGaA, Darmstadt, Germany

Completed

EMD 521873 Plus Radiotherapy in Non Small Cell Lung Cancer (NSCLC)

Lung Cancer | Non Small Cell Lung Cancer

Netherlands

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