Search clinical trials for: intracellular signaling

Total 381 results

OmicsWay Corp.
Oncobox Ltd., Russia; Vitamed LLC, Russia; Republican Oncological Dispensary...

Active, not recruiting

Molecular Pathway Activation Markers Predicting Efficacy of Trastuzumab Therapy for HER2-positive Breast Cancer

HER2-positive Breast Cancer

United States, Russian Federation
OmicsWay Corp.
Oncobox Ltd; Vitamed LLC; N.N. Blokhin National Medical Research Center of Oncology and other collaborators

Active, not recruiting

Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy

Cancer

Russian Federation, United States
University of North Carolina, Chapel Hill
Tibotec Pharmaceutical Limited

Completed

Differences in Evoked Intracellular Interferon Signaling Pathways Using Single Cell Phosphoprotein Profiling

Hepatitis C

United States
University of Thessaly

Completed

Protein Supplementation and Skeletal Muscle Healing Process

Skeletal Muscle Performance | Skeletal Muscle Damage | Exercise-induced Aseptic Inflammation | Intracellular Signaling in Skeletal Muscle | Proteasome Activation

Greece
University of Aarhus

Completed

A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis

Diabetes Mellitus Type 1 | Ketoacidosis

Denmark
Democritus University of Thrace

Completed

NAC Supplementation and Skeletal Muscle Performance

Skeletal Muscle Performance | Skeletal Muscle Damage | Intgracellular Signaling in Skeletal Muscle | Inflammatory Status

Greece
University of Aarhus

Completed

Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction

Healthy

Denmark
Medical Center Alkmaar

Unknown

Dipeptide Alanyl Glutamine and Postoperative Insulin Resistance in Colon Carcinoma Patients (AIRCo)

Colon Carcinoma

Netherlands
Universitaire Ziekenhuizen KU Leuven

Unknown

Study of Polymorphisms in pear1 Gene Link to Platelet Activation and Signaling Pathway Variations

Platelet Function

Belgium
University of Aarhus
MR Research Center, Skejby Sygehus, Brendstrupgaardsvej 100, 8200 Aarhus N

Terminated

Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism

Hypothyroidism

Denmark
Aarhus University Hospital

Completed

Peripheral Effects of Endotoxin on Insulin Resistance

Healthy

Denmark
University of Aarhus

Completed

Growth Hormone Signaling in Vivo in Humans

Intracellular Signaling Peptides and Proteins

Denmark
Xie Kangjie

Recruiting

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Diabetes | Postoperative Delirium

China
Mannkind Corporation

Not yet recruiting

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension (ICoN-1)

Mycobacterium Infections, Nontuberculous | MAC Lung Disease | Treatment Refractory MAC Lung Disease

United States
University Hospital, Antwerp
Universiteit Antwerpen; AZ Jan Palfijn Gent

Not yet recruiting

Diagnosing Drug Allergy: the T is the Key (TAT)

Amoxicillin Allergy
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
University of Miami

Recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer (OCEAN)

Prostate Cancer | Prostate Adenocarcinoma | Hormone Sensitive Prostate Cancer

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
University of Oxford
British Heart Foundation; Oxford University Hospitals NHS Trust

Not yet recruiting

Intracellular Magnesium and Heart Failure

Heart Failure With Preserved Ejection Fraction | Hypomagnesemia

United Kingdom
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
IRCCS Burlo Garofolo

Recruiting

Defects of Keratinocytes Function in Dermatologic Patients

Hidradenitis Suppurativa

Italy
University College, London
Novartis; Cancer Research UK; Janssen Pharmaceutica NV

Not yet recruiting

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (STAMPEDE2)

Prostate Cancer Metastatic
University of Alabama at Birmingham

Not yet recruiting

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway (VITAL-IMPACT)

Cardiovascular Diseases | Obesity | Insulin Sensitivity/Resistance | Metabolic Disease | Energy Expenditure | Metabolism

United States
Pasithea Therapeutics Corp.

Recruiting

PAS-004 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF Mutation

United States
University Health Network, Toronto
Western University, Canada; Public Health Ontario Laboratory, Canada

Recruiting

M. Avium WGS During Mav-PD Treatment

Respiratory Tract Diseases | Mycobacterium Infections | Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Avium

Canada
Rigshospitalet, Denmark

Not yet recruiting

The Effects of HER2 Receptor Signaling on Human Brown Fat Activity (HEAT)

Breast Cancer

Denmark
Chulalongkorn University
King Chulalongkorn Memorial Hospital

Recruiting

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG (CMD03DIPG)

Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor

Thailand
VA Office of Research and Development
University of Wisconsin, Madison; National Center for PTSD

Not yet recruiting

mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders (MEASURE-BD)

Bipolar Disorder

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Trieste; IRCCS Fondazione Stella Maris; CNR Institute of Neuroscience...

Recruiting

Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) (GAPsy)

Healthy | Depression, Anxiety

Italy
Case Comprehensive Cancer Center
National Institutes of Health (NIH)

Recruiting

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Prostate Cancer | Malignant Neoplasm of Prostate | Secondary Malignant Neoplasm of Prostate

United States
Duke University
Memorial Sloan Kettering Cancer Center; University of Wisconsin, Madison

Recruiting

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials (ARCTIC)

Prostate Cancer | Castration-resistant Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

Obesity | Muscle Weakness | Insulin Resistance | Adiposity | Insulin Sensitivity

United States
Physicians Committee for Responsible Medicine
Yale University

Recruiting

The Effect of a Low-fat Vegan Dietary Intervention on Intracellular Lipid, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes Mellitus Type 2 in Obese

United States
Beth Israel Deaconess Medical Center

Recruiting

Purinergic Signaling and the Postmenopausal Heart

Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure

United States
National Taiwan University Hospital

Recruiting

Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling

Brain Cancer | Brain Tumor

Taiwan
National Taiwan University Hospital

Recruiting

Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling-Establish Reliably Electrophysiological Readouts From Human-induced Pluripotent Stem Cells (hiPSCs)-Derived Cerebral Organoids and Surgically Dissected Human Live Brains

Brain Diseases | Brain Tumor

Taiwan
Catherine Spina
Arcus Biosciences, Inc.

Recruiting

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer (SBRT-AMICO)

Oligometastatic Prostate Cancer

United States
Radboud University Medical Center

Recruiting

A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study (MAC-PD cohort)

Mycobacterium Avium Complex Pulmonary Disease

Korea, Republic of, United States, Croatia, Japan, Netherlands
Radboud University Medical Center

Recruiting

Pharmacokinetic Study of Minocycline in Patients With Pulmonary Nontuberculous Mycobacterial Disease (Mino-PK)

Mycobacterium Avium Complex Pulmonary Disease

Netherlands
Brown University
Cures Within Reach; Lifespan; Legorreta Cancer Center at Brown University

Recruiting

Targeting Androgen Signaling in Urothelial Cell Carcinoma - Neoadjuvant (TASUC-Neo)

Urothelial Carcinoma Bladder | Androgen Receptor Positive

United States
German Heart Institute
Deutsche Stiftung für Herzforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Recruiting

Microvascular Cardiac Allograft Vasculopathy Trial (mCAV)

Cardiac Allograft Vasculopathy

Germany
Shanghai Pulmonary Hospital, Shanghai, China
Karolinska Institutet; Fudan University; University of Sydney; Shanghai Municipal...

Recruiting

Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung Disease

Gram-Positive Bacterial Infections | Mycobacterium Infections | Mycobacterium Avium-Intracellulare Infection | Mycobacterium Avium Complex

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

JAK-i on RA B-lymphocytes Tolerance and Disease Resolution Through JAK Signaling In Rheumatoid Arthritis

Rheumatoid Arthritis

Italy
Hospital del Río Hortega
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa and other collaborators

Recruiting

Supramarginal Resection in Glioblastoma Guided by Artificial Intelligence (SupraGlio-AI)

Glioblastoma

Spain
Novartis Pharmaceuticals

Recruiting

A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea

Non-Small-Cell Lung Carcinoma

Korea, Republic of
Ankara City Hospital Bilkent
Gazi University

Recruiting

The Relationship of Cortical Excitability, Cognitive Functions, and Peripheral Signaling Molecules Following Acute Exercise

Healthy

Turkey
Beth Israel Deaconess Medical Center
Dana-Farber Cancer Institute

Recruiting

Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression

Prostate Cancer | Prostate Adenocarcinoma | Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

United States
Brigham and Women's Hospital

Recruiting

Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP (RECAP-5)

Nasal Polyps | Aspirin-exacerbated Respiratory Disease

United States
Shaw Cancer Center
Steadman Philippon Research Institute

Recruiting

Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients

Radiation Induced Fibrosis

United States
University of California, San Diego

Recruiting

ADRB3 Signaling Pathway in Human Adipose Tissue

Obesity, Prediabetes

United States

Search clinical trials for: intracellular signaling

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