Search clinical trials for: intravitreal aflibercept

Total 1320 results

Ocular Therapeutix, Inc.
Duke University; Fortrea

Recruiting

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Sohag University

Recruiting

Relationship Between Dyslipidemia and The Response of Diabetic Macular Edema to Intravitreal Injection of Anti Vascular Endothelial Growth Factor Agents

Diabetic Macular Edema

Egypt
Innostellar Biotherapeutics Co.,Ltd

Recruiting

Safety and Efficacy of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (VENUS)

Neovascular Age-Related Macular Degeneration

China
Unity Biotechnology, Inc.

Recruiting

Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE) (ASPIRE)

Eye Diseases | Diabetes Mellitus | Retinal Degeneration | Retinal Diseases | Edema | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

United States
Tianjin Medical University Eye Hospital
Abbvie Pharmaceutical Trading (Shanghai) Co., Ltd.

Recruiting

Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial

Diabetic Macular Edema | Pars Plana Vitrectomy | Dexamethasone Intravitreal Implant | Intraoperative Optical Coherence Tomography

China
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Kim's Eye Hospital
Nune Eye Hospital, Seoul, Korea; HanGil Eye Hospital

Not yet recruiting

Choroidal Morphology Changes After Aflibercept Therapy in Pachychoroid Neovasculopathy

Pachychoroid Neovasculopathy
The University of Texas Medical Branch, Galveston

Recruiting

Intravitreal Injection Site and Perceived Pain

Pain

United States
Vista Klinik

Not yet recruiting

Intravitreal Faricimab in Diabetic Macular Edema With Limited Response to Aflibercept

Diabetic Macular Edema
Qena Faculty of medicine, South Valley University

Recruiting

Ranibizumab Versus Aflibercept for CRVO in Young Patients.

Non-Ischemic Central Retinal Vein Occlusion With Macular Edema

Egypt
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

Neovascular (Wet) Age-Related Macular Degeneration

United States, Puerto Rico
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central... and other collaborators

Recruiting

Brolucizumab for CNV Associated With Pathologic Myopia (COASTUAbaCNV)

Pathologic Myopia

Ukraine
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
Kim's Eye Hospital
Bayer

Recruiting

Treat-and-extend Using Aflibercept for Type 3 Neovascularization

Retinal Angiomatous Proliferation

Korea, Republic of
M. Ali Khan, MD
University of California, Los Angeles; Southeastern Retina Associates; Eye Associates...

Recruiting

Intravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment Repair (PREVENT-PVR)

Proliferative Vitreoretinopathy | Retinal Detachment With Multiple Breaks, Unspecified Eye

United States
Centre Hospitalier Universitaire de Nice

Recruiting

Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated With Proton Therapy for a Large Choroidal Melanoma (PROTECT)

Ocular Melanoma

France
Unity Health Toronto

Recruiting

Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept (COVARIANT)

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

Canada
Medical University of Vienna

Recruiting

Aflibercept in Recurrent or Persistent CNV (OPHTH-010915)

Diabetic Macular Edema | Age Related Macular Degeneration | Intravitreal Injections

Austria
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) (DAYLIGHT)

Wet Age-related Macular Degeneration

United States, Puerto Rico
University of Athens

Completed

Intravitreal Aflibercept for Macular Edema Due to Central Retinal Vein Occlusion (INTRAMED-CRVO)

Retinal Vein Occlusion | Vascular Occlusive Disease
Bayer

Completed

A Study to Learn How Safe the Study Drug Intravitreal (Given by an Injection Into the Eye) Aflibercept is in Participants in India With Diabetic Macular Edema (VISION-AF)

Diabetic Macular Edema

India
Jaeb Center for Health Research

Completed

DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME (DRCR AC)

Diabetic Macular Edema

United States
Singapore National Eye Centre
National University Hospital, Singapore; Tan Tock Seng Hospital

Active, not recruiting

Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

Polypoidal Choroidal Vasculopathy

Singapore
Fondation Ophtalmologique Adolphe de Rothschild
Bayer

Active, not recruiting

Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic Determinant of Central Retinal Vein Occlusions (CRVO) in Patients With or Without Intravitreal Aflibercept Injections (PULSOV)

Central Retinal Vein Occlusion

France
Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KITE)

Diabetic Macular Edema

Czechia, India, Russian Federation, Taiwan, Turkey, Lebanon, Denmark, Estonia, France, Germany, Hungary, Korea, Republic of, Latvia, Lithuania, Bulgaria, Norway, Belgium, Malaysia, Sweden, Slovakia, Singapore, Poland, Switzerland
University of Oklahoma

Completed

Aflibercept Injection for Proliferative Diabetic Retinopathy

Vitreous Hemorrhage

United States
Kim's Eye Hospital

Completed

Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCV

Age-Related Macular Degeneration | Choroidal Neovascularization | Polypoidal Choroidal Vasculopathy

Korea, Republic of
Bayer
Regeneron Pharmaceuticals

Completed

Intravitreal Aflibercept Injection in Vision Impairment Due to DME (VIVID-DME)

Diabetes Mellitus | Macular Edema

France, Japan, Australia, Austria, Poland, Czechia, Denmark, Germany, Hungary, Italy, Spain
Bayer
Regeneron Pharmaceuticals

Completed

Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye (ARIES)

Macular Degeneration

Spain, Hungary, United Kingdom, Australia, Italy, Canada, France, Germany
Bayer
Regeneron Pharmaceuticals

Completed

Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema (APOLLON)

Diabetic Retinopathy

France
Larkin Community Hospital

Completed

Role of Intravitreal Aflibercept Injection for the Treatment of Radiation Maculopathy

Adverse Effect of Radiation Therapy
European School of Advanced Studies in Ophthalmology

Completed

Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome

Diabetic Macular Edema

Switzerland
University of Nebraska
Regeneron Pharmaceuticals

Completed

Pharmacokinetic Study of Intravitreal Aflibercept Injection in Eyes With Wet Age-related Macular Degeneration (DRAW)

Neovascular Macular Degeneration

United States
Greater Houston Retina Research
Regeneron Pharmaceuticals; Clinical Trials Resource Group, LLC

Active, not recruiting

Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial (VOYAGE)

Diabetic Retinopathy

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for DME (INFINITY)

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for Wet AMD (OPTIC)

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
Innovent Biologics (Suzhou) Co. Ltd.

Suspended

Evaluation of IBI302 Injection in nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

China
Regeneron Pharmaceuticals

Completed

Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity (BUTTERFLEYE)

Retinopathy of Prematurity

United States, Bulgaria, Hungary, Russian Federation, Thailand, Turkey, Colombia, Czechia, Korea, Republic of, Romania, Slovakia, Taiwan, Vietnam
Alimera Sciences

Active, not recruiting

A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME) (NEW DAY)

Diabetic Macular Edema

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National... and other collaborators

Completed

Anti-VEGF Treatment for Prevention of PDR/DME

Diabetic Retinopathy | Diabetic Macular Edema

United States, Canada
Bayer

Completed

A Study to Learn More About How Drug Aflibercept Works in Canadian Patients With Reduced Vision Caused by New Blood Vessels Growing in the Eye (Myopic Choroidal Neovascularization or mCNV) (REALM)

Myopic Choroidal Neovascularization

Canada
Novartis Pharmaceuticals

Completed

To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema (KINGLET)

Diabetic Macular Edema

China
Bayer

Completed

Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice

Wet Age-related Macular Degeneration

India
Bayer
Regeneron Pharmaceuticals

Completed

Observational Study to Assess Intravitreal Aflibercept Injections Used in a "Treat and Extend" Regimen in Treatment-naïve Wet Age-related Macular Degeneration Patients (ASTERIA)

Wet Age-related Macular Degeneration

Switzerland
The Cleveland Clinic
Allergan

Active, not recruiting

Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema (PRECISION)

Diabetic Macular Edema

United States
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit

Neovascular Age-related Macular Degeneration (nAMD)

United States
Dar El Oyoun Hospital

Completed

Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous Chorioretinopathy (CSCR)

Central Serous Chorioretinopathy

Egypt
Bayer

Completed

Study to Gather Information on the Safety and Use of Aflibercept Injections Into the Eye for the Treatment of Eye Disorders in Mexican Routine Clinical Practice (MAIA)

Retinal Disease

Mexico
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections (MERLIN)

Age-Related Macular Degeneration

United States, Puerto Rico

Search clinical trials for: intravitreal aflibercept

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