Search clinical trials for: leucovorin

Total 1338 results

Eastern Hepatobiliary Surgery Hospital

Not yet recruiting

A Trial of Adjuvant Therapy After Hepatocarcinoma Resection Based on Folate Receptor-positive Circulating Tumor Cells

Hepatocellular Carcinoma

China
Ralf Hofheinz
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest; Deutsche... and other collaborators

Recruiting

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

Germany
Johannes Laengle, MD, PhD

Not yet recruiting

Immunoscore as Decision Guidance for Adjuvant Chemotherapy in Colon Cancer (iMAGINE)

Colon Cancer Stage III

Austria
Karolinska University Hospital
The Swedish Research Council; University of Leipzig

Recruiting

Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer (NEEDS)

Esophageal Squamous Cell Carcinoma

Canada, Sweden, Norway, Ireland
Hamilton Health Sciences Corporation

Recruiting

Pancreatic Adenocarcinoma Neoadjuvant Chemotherapy Before Surgery (PANCREAS)

Pancreatic Adenocarcinoma

Canada
Krankenhaus Nordwest
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) (PREVENT)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Germany
Blokhin's Russian Cancer Research Center

Recruiting

FOLFOX6 Versus mFOLFIRINOX as First Line Chemotherapy in Metastatic Gastric Cancer or Esophagogastric Junction Adenocarcinoma (Type II-III) (IRIGA)

Gastric Carcinoma Stage IV | Esophagogastric Junction Adenocarcinoma Stage IV

Russian Federation
Seagen Inc.

Recruiting

Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers

Gastric Adenocarcinoma | Cholangiocarcinoma | Esophageal Adenocarcinoma | Colorectal Carcinoma | Gallbladder Carcinoma | GEJ Adenocarcinoma

United States, Japan
Blokhin's Russian Cancer Research Center

Recruiting

FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma (RusGCG-01)

Stomach Neoplasms | Gastrointestinal Neoplasms | Docetaxel | Oxaliplatin | Fluoruracil | Irinotecan Hydrochloride

Russian Federation
Seoul National University Hospital

Recruiting

NaliCap (Irinotecan Liposome (Nal-IRI)/Capecitabine) vs. NAPOLI (Nal-IRI/5-FU/LV) ) in Advanced Pancreatic Cancer (NaliCap)

Pancreatic Cancer

Korea, Republic of
University of Chicago

Recruiting

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies (I-FLOAT)

Adenocarcinoma | Pancreatic Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Toripalimab Combined With FLOT Neoadjuvant Chemotherapy in Patients With Resectable Gastric Cancer

Gastric Cancer

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenosquamous Carcinoma | Resectable Pancreatic Adenocarcinoma

United States, Canada
Sun Yat-sen University

Recruiting

mFOLFOXIRI Versus mFOLFOX6 as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer (FANTASTIC)

Colorectal Cancer

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Peritoneal Carcinomatosis | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Malignant Uterine Neoplasm | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage... and other conditions

United States
University of Saskatchewan

Not yet recruiting

Systemic Therapy With a Loco-regional Treatment in Patients With Locally Advanced Pancreatic Cancer (SMART)

Locally Advanced Pancreatic Cancer | Irreversible Electroporation
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Gastric Adenocarcinoma | Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Gastric Cancer AJCC v8 | Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8 | Clinical... and other conditions

United States
Vejle Hospital

Recruiting

Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer (Toco-CoR)

Colorectal Cancer Metastatic

Denmark
Yanhong Deng

Recruiting

Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer (TRIBE-C)

Colorectal Cancer

China
Yanhong Deng

Recruiting

Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer (FOBEAR)

Rectal Cancer

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Metastatic Small Intestinal Adenocarcinoma | Stage III Small Intestinal Adenocarcinoma AJCC v8 | Stage IIIA Small Intestinal Adenocarcinoma AJCC v8 | Stage IIIB Small Intestinal Adenocarcinoma AJCC v8 | Stage IV Small Intestinal Adenocarcinoma AJCC v8

United States
Sun Yat-sen University

Recruiting

Systemic Chemotherapy Plus Lenvatinib and Toripalimab for HCC With Extrahepatic Metastasis

Hepatocellular Carcinoma

China
University of Nebraska
National Cancer Institute (NCI)

Recruiting

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

Pancreas Cancer | Adenocarcinoma of the Pancreas

United States
Sun Yat-sen University

Recruiting

HAIC Plus Toripalimab vs. HAIC Plus Sorafenib for HCC With PVTT: a Non-comparative, Prospective, Randomized Trial

Hepatocellular Carcinoma

China
Australasian Gastro-Intestinal Trials Group
Trans Tasman Radiation Oncology Group; Australian Government Department of...

Recruiting

MFOLFIRINOX And Stereotactic Radiotherapy (SBRT) for Pancreatic Cancer With High Risk and Locally Advanced Disease (MASTERPLAN)

Pancreatic Cancer

Australia
Southwest Autism Research & Resource Center
United States Department of Defense; State University of New York - Downstate...

Recruiting

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

Autism Spectrum Disorder | Language Disorders

United States
Southwest Autism Research & Resource Center
Autism Speaks; State University of New York - Downstate Medical Center

Recruiting

Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism

Autism Spectrum Disorder | Language Disorders

United States
Ludwig-Maximilians - University of Munich
Amgen; ClinAssess GmbH

Not yet recruiting

Optimal Anti-EGFR Treatment of mCRC Patients With Low-Frequency RAS Mutation

Treatment Related Cancer

Germany
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Recruiting

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) (CheckMate 8HW)

Metastatic Colorectal Cancer

United States, Belgium, China, Canada, Denmark, France, Norway, Romania, Spain, United Kingdom, Austria, Brazil, Germany, Netherlands, Argentina, Czechia, Ireland, Italy, Turkey, Chile, Greece, Puerto Rico, Australia, Japan
Georgetown University
Ipsen

Recruiting

NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer

Advanced Biliary Tract Cancer

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Odense University Hospital; Medical University of Vienna; Maastricht University... and other collaborators

Recruiting

Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancer (NAPAN)

Metastatic Pancreatic Cancer

Netherlands
UNC Lineberger Comprehensive Cancer Center

Recruiting

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

Pancreatic Neoplasms | Pancreas Adenocarcinoma | Pancreatic Cancer Resectable | Cancer of Pancreas | Pancreatic Cancer Non-resectable | Pancreatic Ductal Adenocarcinoma (PDAC) | Pancreatic Cancer, Adult

United States
Jonsson Comprehensive Cancer Center
Bristol-Myers Squibb; NovoCure Ltd.

Recruiting

Nivolumab in Combination With Chemotherapy Pre-Surgery in Treating Patients With Borderline Resectable Pancreatic Cancer

Borderline Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States, Canada, Australia, Puerto Rico, New Zealand
National Cancer Institute (NCI)

Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Down Syndrome | B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States, Puerto Rico, Australia, Canada, New Zealand
Bristol-Myers Squibb
Novartis; Clovis Oncology, Inc.; Janssen Pharmaceuticals; Exelixis

Recruiting

Pan Tumor Rollover Study

Cancer

United States, Israel, Spain, Italy, Germany, Australia, Belgium, China, Korea, Republic of, Greece, Japan, Argentina, Austria, Brazil, Canada, Chile, Denmark, Finland, France, Hungary, Ireland, Mexico, Netherlands, Poland, Romania, Russian... and more
Toray Industries, Inc

Recruiting

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Cholangiocarcinoma | Bladder Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer | Palpable Subcutaneous Malignant Lesions

United States, France
GERCOR - Multidisciplinary Oncology Cooperative...
OSE Immunotherapeutics

Recruiting

Maintenance With OSE2101 Plus FOLFIRI, or FOLFIRI After FOLFIRINOX-based Induction Therapy in Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (TEDOPAM)

Metastatic Cancer | Pancreatic Ductal Adenocarcinoma | Locally Advanced Cancer

France
Emory University
University of Pittsburgh; Hematology/Oncology Pharmacy Association

Recruiting

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

Malignant Digestive System Neoplasm

United States
Mian XI

Recruiting

PET Imaging-guided Chemoradiotherapy in Esophageal Squamous Cell Carcinoma

Squamous Cell Carcinoma | Neoplasm, Esophageal

China
Sun Yat-sen University

Recruiting

HAIC Plus H101 vs HAIC Alone for Unresectable HCC at BCLC A-B

Hepatocellular Carcinoma

China
UNICANCER

Recruiting

Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer (ARION)

Esophagus Cancer | Unresectable Malignant Neoplasm

France
Academisch Medisch Centrum - Universiteit van Amsterdam...
Servier

Recruiting

Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer (LyRICX)

Esophageal Cancer

Netherlands
Benaroya Research Institute

Recruiting

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

Pancreatic Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center
University of Alabama at Birmingham

Recruiting

LTA Pilot Study of Glucarpidase in Patients With Central Nervous System Lymphoma

Central Nervous System Lymphoma

United States
Yonsei University

Recruiting

A Study of Bevacizumab, Infusional Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab, Infusional Fluorouracil, Leucovorin, and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer

Unresectable Metastatic Right-sided Colon Cancer Starting First-line Combination Chemotherapy | Unresectable Metastatic Right-sided Colon Cancer, Stage IV

Korea, Republic of
Khon Kaen University

Recruiting

Neoadjuvant mFOLFOXIRI for Potentially Resectable Cholangiocarcinoma

Cholangiocarcinoma

Thailand
Centro Ricerche Cliniche di Verona

Recruiting

A Study of Nal-IRI With 5-FU, Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer (nITRo)

Pancreatic Adenocarcinoma

Italy
Astellas Pharma Global Development, Inc.

Recruiting

A Study to Assess the Antitumor Activity, Safety, Pharmacokinetics and Biomarkers of Zolbetuximab (IMAB362) in Participants With Claudin (CLDN) 18.2 Positive, Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma (ILUSTRO)

Gastric Cancer | Pharmacokinetics of Zolbetuximab | Gastro-esophageal Junction (GEJ) Cancer | Pharmacokinetics of Oxaliplatin | Pharmacokinetics of Fluorouracil Bolus (5-FU)

United States, Italy, Japan, Korea, Republic of, Taiwan, France
Kyungpook National University Hospital

Recruiting

Neoadjuvant FOLFOX Chemotherapy for Patients With Locally Advanced Colon Cancer

Colon Cancer

Korea, Republic of

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