Search clinical trials for: linezolid (LZD)

Total 183 results

Harvard Medical School (HMS and HSDM)
National Institute of Allergy and Infectious Diseases (NIAID); Partners in... and other collaborators

Recruiting

Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens (STEM-TB)

HIV | Tuberculosis, Multidrug-Resistant

Kazakhstan, Lesotho, Peru
Boston University
Harvard Medical School (HMS and HSDM); University of Colorado, Denver; National... and other collaborators

Recruiting

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB (DRAMATIC)

Tuberculosis, Multidrug-Resistant

Philippines, Vietnam
University of California, San Francisco
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)

Tuberculosis, Meningeal

Uganda
National Institute of Allergy and Infectious Diseases...

Recruiting

Linezolid Dosing Strategies in Drug-Resistant TB

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant

Brazil, India, Kenya, Philippines, South Africa, Zimbabwe, Thailand, Haiti, Peru, Botswana
Huashan Hospital

Active, not recruiting

Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T)-PLUS (TB-TRUSTplus)

Multidrug Resistant Tuberculosis

China
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
Clinical Research Centre, Malaysia

Not yet recruiting

Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia (EVOS)

Staphylococcus Aureus Bacteremia

Malaysia
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Recruiting

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis

Drug Sensitive Tuberculosis | Pulmonary Tuberculosis | Pulmonary TB

Philippines, South Africa, Tanzania, Georgia, Uganda
Helwan University

Recruiting

The Incidence of Linezolid-induced Thrombocytopenia (LIT) in Critically Ill Patients, the Risk Factors for LIT

Thrombocytopenia; Drugs

Egypt
Helwan University

Recruiting

The Effect of NAC in Decreasing the Incidence of Linezolid-induced Thrombocytopenia in Critically Ill Patients

Linezolid Induced Thrombocytopenia

Egypt
Ain Shams University

Recruiting

Efficacy and Safety of Continuous Versus Intermittent Linezolid Infusion in Critically Ill Patients With Septic Shock

Treatment Efficacy

Egypt
Cluj Municipal Clinical Hospital
Iuliu Hatieganu University of Medicine and Pharmacy

Recruiting

Pharmacokinetics and Pharmacodynamics of Linezolid Continuous and Intermittent Administration

Critical Illness | Pharmacokinetics | Efficacy | Side-effect of Antibiotic | Intensive Care Unit ICU

Romania
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
National Department of Health, Papua New Guinea; School of Medicine and Health...

Recruiting

Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws) (Trep-AByaws)

Yaws | Cutaneous Ulcer

Papua New Guinea
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Linezolid or Vancomycin Surgical Site Infection Prophylaxis (LOVip)

General Surgery | Antibiotic Prophylaxis

France
University of Southern California
The University of Texas Health Science Center, Houston; Universidad Peruana...

Recruiting

Linezolid for Syphilis Pilot Study

Syphilis

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) (TEDITUB)

Tuberculosis | Multidrug Resistant Tuberculosis

France
Fundacion Clinic per a la Recerca Biomédica

Not yet recruiting

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis (OraPAT-IEGAMES)

Endocarditis Infective

Spain
MicuRx

Recruiting

Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)

Diabetic Foot Infection

Spain, China, United States, Estonia, Latvia, Portugal, Bulgaria, Greece, Italy, Lithuania, Puerto Rico
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

A Phase Ⅱ Clinical Study of 9MW1411 Injection in Acute Bacterial Skin and Skin Structure Infections

Skin Infection

China
Treeway B.V.

Recruiting

ASURE: Alzheimer Study Using oRal Edaravone

Alzheimer Disease

Croatia, Netherlands
Beijing Chest Hospital

Recruiting

A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in China (PROSPECT)

Tuberculosis, Multidrug-Resistant

China
Wake Forest University Health Sciences

Recruiting

NextGen - Clinical Implication of Next Generation Sequencing

Urinary Tract Infections

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Recruiting

Alternative Antibiotics for Syphilis

Primary Syphilis | Secondary Syphilis | Early Latent Syphilis

Spain, United Kingdom
Shandong University
Children's Hospital of Chongqing Medical University

Recruiting

Population Pharmacokinetics of Commonly Used Antimicrobial Agents in Children of Bacterial Meningitis With Augmented Renal Clearance

Bacterial Meningitis | Augmented Renal Clearance

China
Beijing Chest Hospital

Recruiting

Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis

Tuberculosis

China
October 6 University
Beni-Suef University

Recruiting

Continuous Infusion of Linezolid Versus Intermittent Dosing in the Treatment of Nosocomial Pneumonia

Pneumonia

Egypt
The University of Queensland
University of Copenhagen; Erasmus Medical Center; Monash University; Hôpital Cochin and other collaborators

Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT)

Pulmonary Disease Due to Mycobacteria (Diagnosis)

Australia, Canada, Denmark, France, Ireland, Netherlands, New Zealand, United Kingdom, Singapore
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis (INTENSE-TBM)

Tuberculous Meningitis

Côte D'Ivoire, Madagascar, South Africa, Uganda
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
National Taiwan University Hospital

Recruiting

Investigation of the Correlation Between Plasma Concentration of Linezolid Antibiotic and Treatment Response and Adverse Reactions

Peripheral Neuropathy | Lactic Acidosis | Myelosuppression

Taiwan
University Hospital, Lille
Ministry of Health, France

Recruiting

Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis (TAVeM2)

Critical Illness | Mechanical Ventilation Complication

France
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Liverpool; Ministry... and other collaborators

Completed

Economic Evaluation of New MDR TB Regimens (PRACTECAL-EE)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculoses | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Sussex; Ministry... and other collaborators

Completed

Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial (PRACTECAL-PRO)

Multidrug Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Sohag University

Completed

Studying the Distribution of Accessory Gene Regulator (Agr) Quorum Sensing System and the Prevalence of Linezolid and Mupirocin Resistance in Biofilm Producer/Non Producer Staphylococcus Aureus in Sohag University Hospitals

Staphylococcus Aureus

Egypt
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
Vinay Badhwar

Enrolling by invitation

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) (OPTIMAL)

Endocarditis

United States
Michael Pulsipher, MD

Active, not recruiting

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Severe Aplastic Anemia

United States
Imperial College London
Hammersmith Hospitals NHS Trust

Completed

Oral Antibiotic Treatment at Home Instead of Intravenous Treatment in Hospital for Resistant Gram Positive Infections

Staphylococcal Infections | Gram-positive Bacterial Infections

United Kingdom
Universitas Padjadjaran
Radboud University Medical Center; Global Alliance for TB Drug Development

Completed

Pharmacokinetic Study of Linezolid for TB Meningitis (SIMPLE)

Tuberculosis, Meningeal | Linezolid

Indonesia
MicuRx

Completed

MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Bacterial Infections
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Completed

Evaluating Newly Approved Drugs for Multidrug-resistant TB (endTB)

Tuberculosis, Multidrug-Resistant | Infection, Bacterial | Pulmonary Tuberculoses

Pakistan, Georgia, India, Kazakhstan, Lesotho, Peru, South Africa
University College, London
National University Hospital, Singapore; Singapore Clinical Research Institute...

Completed

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis (TRUNCATE-TB)

Tuberculosis, Pulmonary

Singapore, Uganda, Thailand, Indonesia, Philippines, India
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of

Search clinical trials for: linezolid (LZD)

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