Search clinical trials for: lipid synthesis

Total 18389 results

Beijing Chest Hospital
The First Affiliated Hospital with Nanjing Medical University; Anhui Chest... and other collaborators

Recruiting

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

Tuberculosis | Treatment | Adjuvant

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Jemincare

Not yet recruiting

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Solid Tumor, Adult
Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Human Sciences...

Recruiting

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa (ThiPhiSA)

Tuberculosis

South Africa
Freundeskreis Für Internationale Tuberkulosehilfe...

Not yet recruiting

1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam

Tuberculosis Infection

Vietnam
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Healthy Subjects

China
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Recruiting

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis

Drug Sensitive Tuberculosis | Pulmonary Tuberculosis | Pulmonary TB

Philippines, South Africa, Tanzania, Georgia, Uganda
University of Southern California

Not yet recruiting

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

Emergency General Surgery | Trauma Abdomen | Laparotomy | Surgical Site Infections | Dehiscence Wound

United States
Huashan Hospital

Recruiting

TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts (TB-YOUTH)

Latent Tuberculosis | Tuberculosis

China
Queen Mary University of London
University of Washington; University of Oxford; KEMRI-Wellcome Trust Collaborative... and other collaborators

Not yet recruiting

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM (Co-SAM)

HIV | Severe Acute Malnutrition | Comorbidities and Coexisting Conditions | Child Malnutrition
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa, Philippines
Indian Council of Medical Research
Christian Medical College, Vellore, India; Jawaharlal Institute of Postgraduate... and other collaborators

Not yet recruiting

Intensified Short Course Regimen for TBM in Adults (INSHORT)

Tuberculous Meningitis

India
University of Illinois at Urbana-Champaign

Recruiting

The Anabolic Properties of a Lipid-rich Pork Matrix

Muscle Protein Synthesis

United States
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare; Mylan Inc.

Recruiting

Pharmacokinetics and Safety of Double-dose Dolutegravir When Used With Rifapentine for HIV-associated Tuberculosis

HIV-associated Tuberculosis

South Africa, Thailand
Stellah Mpagama
Radboud University Medical Center; University of St Andrews

Recruiting

A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis (OptiRiMoxTB)

Tuberculosis | Human Immunodeficiency Virus

Tanzania
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) (TEDITUB)

Tuberculosis | Multidrug Resistant Tuberculosis

France
TASK Applied Science

Recruiting

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 (BETO)

Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

South Africa
Emory University
National Cancer Institute (NCI)

Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
First Affiliated Hospital of Zhejiang University

Not yet recruiting

Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment

Tuberculosis, Pulmonary
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); Federal University... and other collaborators

Recruiting

Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention

Tuberculosis Infection | Isoniazid Adverse Reaction

Brazil
Rutgers, The State University of New Jersey

Recruiting

One-month Latent Tuberculosis Treatment for Renal Transplant Candidates

End Stage Renal Disease | Latent Tuberculosis | Renal Transplant Candidate for Right Kidney | Renal Transplant Candidate for Left Kidney

United States
Huashan Hospital

Recruiting

Optimizing(O) RIfapentine-based(RI) Regimen and shortENing(EN) the Treatment of Drug-sensitive Tuberculosis(T) (ORIENT)

Tuberculosis, Pulmonary

China
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
West China Hospital

Not yet recruiting

The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation (PTTKT)

Tuberculosis | Kidney Transplant Infection | Isoniazid Toxicity
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
Fudan University

Recruiting

Reverse Triple Negative Immune Resistant Breast Cancer (Renaissance)

Triple-negative Breast Cancer

China
Miguel Santín
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Not yet recruiting

Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney Disease

Latent Tuberculosis | Kidney Failure
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Congenital Pure Red Cell Aplasia | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline... and other conditions

United States
University of Cape Town

Recruiting

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

HIV | Disseminated Tuberculosis

South Africa
Chelsea and Westminster NHS Foundation Trust

Recruiting

The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers

HIV-1-infection

United Kingdom
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Cardiac Risk After Discontinuing Abacavir Treatment in HIV-infected Individuals (AVERTAS-1)

Cardiovascular Diseases | HIV Infections | Hiv | Weight Change, Body | HIV Lipodystrophy | HIV Cardiomyopathy

Denmark
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil (AVERTAS-2)

HIV Infections | Obesity | Renal Insufficiency | Osteoporosis | Hiv | Weight Gain | HIV Lipodystrophy

Denmark
John Sievenpiper

Not yet recruiting

Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction

Dyslipidemias | Cardiovascular Risk Factor | Dysglycemia

Canada
Kaohsiung Veterans General Hospital.
Chang Gung Memorial Hospital; Taipei Veterans General Hospital, Taiwan; National... and other collaborators

Not yet recruiting

Evaluation of the Efficacy and Safety of a 4-month Daily Regimen (2HZPM/2HPM) for Treatment of Pulmonary TB (ESCAPE-TB)

Tuberculosis, Pulmonary

Taiwan
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC

Recruiting

Doravirine Versus Integrase Inhibitors on Backbone of Emtricitabine and Tenofovir Alafenamide in HIV

Lipid Metabolism Disorders | Cardiovascular Risk Factor | HIV I Infection

United States
Hospital Universitari Vall d'Hebron Research Institute
Radboud University Medical Center; University Medical Center Groningen; Centro... and other collaborators

Not yet recruiting

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (RIAlta)

Tuberculosis

Spain, Netherlands, Paraguay, Portugal
Dr. Nyanda Elias Ntinginya
King's College London; Makerere University; Stichting Katholieke Universiteit-... and other collaborators

Recruiting

Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (PROTID)

Diabetes Mellitus | Tuberculosis

Uganda, Tanzania
Beijing Chest Hospital

Recruiting

Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis

Tuberculosis

China
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

HIV Infections | Tuberculosis

United States, Malawi, Puerto Rico, South Africa, Thailand, Zimbabwe, Brazil, Kenya, Uganda, India, Tanzania, Botswana

Search clinical trials for: lipid synthesis

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