Search clinical trials for: locoregional therapy

Total 51825 results

Zhejiang Cancer Hospital

Not yet recruiting

Sintilimab Combination Therapy Plus IMRT in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma
Sun Yat-sen University

Recruiting

Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma | Bevacizumab | Anti-PD1/PDL1 Antibody

China
Chen Xiaoping

Recruiting

Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy.

Hepatocellular Carcinoma

China
Sun Yat-sen University

Recruiting

Localized Treatment Versus Palliative Chemotherapy in CRC Patients With 10 or More CRLM

Colorectal Neoplasms Malignant

China
National Cancer Institute, Egypt

Recruiting

Metastases Directed Therapy for Oligometastatic Breast Cancer

Breast Cancer | Metastatic Cancer | Metastatic Breast Cancer

Egypt
Ruijin Hospital

Recruiting

Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Eye & ENT Hospital of Fudan University

Recruiting

A Prospective Exploratory Clinical Study of Metronomic Capecitabine as Adjuvant Therapy in Locoregionally Advanced Hypopharyngeal Carcinoma

to Explore Whether the Adjuvant Therapy of Metronomic Capecitabine Could Improve the Disease-free Survival of Locoregionally Advanced Hypopharyngeal Carcinoma

China
Samsung Medical Center

Recruiting

Oncologic Outcomes and Toxicities of Salvage Treatment in Patients With Locoregionally Recurrent Breast Cancer (SALT-LRR)

Breast Cancer

Korea, Republic of
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Sun Yat-sen University

Not yet recruiting

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeting Drugs / Locoregional Therapy for Hepatocellular Carcinoma

China
University of Texas Southwestern Medical Center
Genentech, Inc.

Recruiting

LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC (LOST-B)

Hepatocellular Carcinoma

United States
Wei Jiang
Wuzhou Red Cross Hospital; Laibin People's Hospital; Lingshan people's Hospital; Nanxishan Hospital of Guangxi Zhuang Autonomous Region and other collaborators

Recruiting

Induction Chemotherapy Followed by IMRT or Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Downstaging Protocol Containing Immunotherapy for HCC Beyond the Milan Criteria Before Liver Transplantation (HLPDTLT)

Liver Transplantation | Hepatocellular Carcinoma

China
Guangxi Medical University
Wuzhou Red Cross Hospital; Wuhan Union Hospital, China; Yunnan Cancer Hospital; Hainan People's Hospital and other collaborators

Not yet recruiting

PD-1 Inhibitor Plus GP as Neoadjuvant Therapy for Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Neoadjuvant Therapy | PD-1 Inhibitor
Sun Yat-sen University

Not yet recruiting

Peramprizumab Combined With GP ± Anlotinib as Neoadjuvant Therapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma
Sun Yat-sen University

Recruiting

Neoadjuvant Therapy of GP Chemotherapy Combined With Tislelizumab in Locoregionally Advanced NPC

Nasopharyngeal Carcinoma

China
Translational Research in Oncology
Bayer

Recruiting

Regorafenib-pembrolizumab vs. TACE/TARE in Intermediate Stage HCC Beyond Up-to-7 (REPLACE)

Carcinoma, Hepatocellular

Korea, Republic of, United States, Taiwan, Spain, Japan, France, Georgia, Germany, Turkey, Italy, Belgium, Hong Kong, Serbia
The University of Hong Kong

Recruiting

Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Hong Kong
Sun Yat-sen University
Zhejiang Cancer Hospital; Xijing Hospital; Xiangya Hospital of Central South... and other collaborators

Recruiting

Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition

Nasopharyngeal Carcinoma | Nutrition Therapy

China
Jiangsu Cancer Institute & Hospital

Not yet recruiting

Endostar Combined With Induction Chemotherapy and Concurrent Chemoradiotherapy for Locoregional Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma
Lund University Hospital

Recruiting

Photon Therapy Versus Proton Therapy in Early Tonsil Cancer. (ARTSCAN V)

Tonsil Cancer

Sweden
ETOP IBCSG Partners Foundation
Pfizer

Recruiting

Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer (POLAR)

Breast Cancer Recurrent

Switzerland, Italy, France, Spain, Hungary, Austria
AstraZeneca

Active, not recruiting

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma (EMERALD-1)

Hepatocellular Carcinoma

United States, Canada, France, Taiwan, Thailand, Vietnam, Italy, Korea, Republic of, Brazil, India, Japan, Mexico, Russian Federation, China, Hong Kong, Australia, Spain, Singapore
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage... and other conditions

United States, Canada
Hoffmann-La Roche

Completed

A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

Carcinoma, Hepatocellular

Spain
National Cancer Institute (NCI)

Active, not recruiting

Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin

Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Laryngeal Squamous Cell Carcinoma AJCC... and other conditions

United States, Canada
HistoSonics, Inc.

Active, not recruiting

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER US)

Liver Neoplasms | Hepatocellular Carcinoma | Liver Metastases

United States
Huai'an First People's Hospital
The Second People's Hospital of Huai'an; lian shui county People's Hospital; xuyi... and other collaborators

Completed

Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Replimune Inc.
Bristol-Myers Squibb

Withdrawn

Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN

Squamous Cell Carcinoma of Head and Neck | Recurrent Head and Neck Squamous Cell Carcinoma | Locally Advanced Head and Neck Squamous Cell Carcinoma

United States, Spain, United Kingdom, Czechia, France, Germany, Greece, Poland
M.D. Anderson Cancer Center

Withdrawn

Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma
University of Chicago

Active, not recruiting

Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer (OPTIMA-II)

HNSCC | HPV-Related Squamous Cell Carcinoma

United States
Erasme University Hospital
Terumo Europe N.V.

Completed

Safety and Feasibility of Radioembolization Using Ho-166 in Patients With Unresectable Hepatocellular Carcinoma (RETOUCH)

Hepatocellular Carcinoma

Belgium
Mayo Clinic

Terminated

Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer

Head and Neck Cancer

United States
Boston Scientific Corporation

Terminated

Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer

Esophageal Cancer | Squamous Cell Carcinoma | Adenocarcinoma of the Esophagus

United States, India, Czechia, Poland
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Efficacy of a Locoregional Anesthesia Technique During Shock Wave Therapy

Plantar Fascitis | Achilles Tendinopathy

Italy
University Health Network, Toronto
Novartis Pharmaceuticals

Completed

Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck | Locoregionally Advanced

Canada
Karolinska Institutet

Withdrawn

Individualized Locoregional Treatment of Initially Biopsy-proven Node-positive Breast Cancer After Primary Systemic Therapy (INDAX)

Breast Cancer
University of Texas Southwestern Medical Center

Completed

Wearable Sensor for Biometrics During Locoregional Therapy for Head and Neck Cancer (FITBIT)

Cancer of Head and Neck

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence

Non-Small-Cell Lung Carcinoma

United States
Danish Breast Cancer Cooperative Group
Novartis; Danish Cancer Society; The Danish Medical Research Council

Terminated

Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer (REAL)

Operable Breast Neoplasms

Denmark
Syneos Health
Oncolys BioPharma Inc

Unknown

Evaluate Efficacy, Immunological Response of Intratumoral/Intralesional Oncolytic Virus (OBP-301) in Metastatic Melanoma

Melanoma Stage Iv | Melanoma Stage III

United States
Sun Yat-sen University

Completed

Delineation of Reducing Clinical Target Volume for Early-stage Nasopharyngeal Carcinoma Patients

Target Volume Delineation | Early-stage Nasopharyngeal Carcinoma | Intensity Modulated Radiation Therapy

China
Sun Yat-sen University

Completed

Target Volume Delineation After NACT in LA-NPCarcinoma Patients Treated With NACT+ CCRT

Nasopharyngeal Carcinoma

China
Austral University, Argentina

Completed

AFP Model and Liver Transplantation.

Liver Transplant Disorder | Liver Carcinoma

Argentina, France
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Yonsei University

Completed

The Efficacy of Involved-field Radiation Therapy for Residual or Locoregionally Recurrent Epithelial Ovarian Cancer After Definitive Treatment; Multi-institutional Clinical Trial

Ovarian Cancer (Epithelial)

Korea, Republic of
Wei Jiang
Wuzhou Red Cross Hospital; Guangxi Naxishan Hospital; LiuZhou People's Hospital; Guigang People's Hospital and other collaborators

Unknown

Induction Chemotherapy Followed by IMRT With or Without Concurrent Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Norwegian University of Science and Technology

Completed

Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer

Depression | Pain | Unspecified Adult Solid Tumor, Protocol Specific | Cachexia

Norway
Angiodynamics, Inc.

Completed

NanoKnife Low Energy Direct Current (LEDC) System in Subjects With Locally Advanced Unresectable Pancreatic Cancer

Pancreatic Adenocarcinoma

Italy
University of Michigan Rogel Cancer Center
Genentech, Inc.

Terminated

Phase II Trial for Patients With Loco-Regional Esophageal Carcinoma

Loco-regional Esophageal Cancer

Search clinical trials for: locoregional therapy

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