Search clinical trials for: long acting muscarininc receptor antagonist

Total 104137 results

GlaxoSmithKline

Completed

Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Argentina, Chile, Romania, Canada
GlaxoSmithKline

Completed

Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD) -Study 2

Pulmonary Disease, Chronic Obstructive

Germany, United States, Korea, Republic of, Czech Republic
University of Alberta

Recruiting

Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use

Healthy

Canada
Centre for Addiction and Mental Health
Janssen Inc.

Recruiting

Risk of Breakthrough Symptoms With Long-Acting Injectable Medications

Schizophrenia | Schizophrenia Relapse

Canada
Go Medical Industries Pty Ltd
National Institute on Drug Abuse (NIDA); Columbia University; University at Buffalo and other collaborators

Not yet recruiting

Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent Persons (GM0020)

Opioid Use Disorder
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

The Impact of Aripiprazole Long-acting on Myelin and Cognition in the Onset of Schizophrenia

Schizophrenia | Cognition Disorder | Myelin Degeneration

Italy
Otsuka Canada Pharmaceutical Inc.
Lundbeck Canada Inc.

Recruiting

Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE) (INITIATE)

Schizophrenia | Schizo Affective Disorder | Bipolar I Disorder

Canada
University of Tennessee Graduate School of Medicine
Mylan Pharmaceuticals Inc

Recruiting

Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD

COPD Exacerbation

United States
Imperial College London
European Research Council

Recruiting

Mechanisms of Adverse Effects of Long-Acting Beta-Agonists in Asthma (MAELABA)

Asthma

United Kingdom
University Hospital, Lille
AstraZeneca

Recruiting

Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics in Stable COPD Patient (OSCIVARI)

Copd

France
Janssen-Cilag International NV

Active, not recruiting

A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings (CASPAR)

Schizophrenia

Rwanda
Otsuka Pharmaceutical Development & Commercialization...
PRA Health Sciences

Completed

A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder

Schizophrenia | Bipolar I Disorder

United States
Mylan Pharma UK Ltd.

Completed

Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD)

COPD

China
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Active, not recruiting

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca
Parexel

Completed

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
Columbia University

Completed

Evaluating Long Acting Beta Agonists Used to Treat Asthma Among Those With Either Arg/Arg or Gly/Gly Genotypes (ARGARG)

Asthma

United States
Ionis Pharmaceuticals, Inc.

Completed

Extension Study of IONIS-GHR-LRx Administered to Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands

Acromegaly

United States, Serbia, Poland, Russian Federation, Hungary, Lithuania
AstraZeneca

Completed

A Study to Assess the Reduction of Daily Maintenance ICS/LABA Treatment Towards Anti-Inflammatory Reliever Treatment in Patients With Severe Eosinophilic Asthma Treated With Benralizumab

Asthma | Severe Eosinophilic Asthma

France, Germany, Italy, United Kingdom
Kindeva Drug Delivery

Completed

Single Blind Cross-over Dose Response Study in Subjects of Two Inhalers of Salmeterol and Fluticasone Propionate

Healthy

United Kingdom
University of California, Los Angeles
National Institute of Mental Health (NIMH); Janssen Scientific Affairs, LLC

Completed

Oral Risperidone Versus Injectable Paliperidone Palmitate for Treating First-Episode Schizophrenia

Schizophrenia (Recent-onset)

United States
University of Maryland, Baltimore

Withdrawn

Long Acting Paliperidone in Dually Diagnosed People With Schizophrenia: An Open-label Pilot Study

Schizophrenia

United States
Martha Sajatovic
Otsuka Pharmaceutical Development & Commercialization, Inc.

Completed

CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)

Bipolar Disorder | Medication Adherence | Medication Non Adherence

United States
Organon and Co

Completed

Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)

Asthma
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics (MAESTRO)

Schizophrenia | Antipsychotics | Long-Acting Injection | LAI | Aripiprazole

Korea, Republic of
Janssen Scientific Affairs, LLC

Completed

A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform (DREaM)

Psychotic Disorders | Schizophrenia

United States, Brazil, Mexico
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study of Fluticasone Propionate MDPI Compared With Fluticasone/Salmeterol MDPI in Adolescent and Adult Patients With Persistent Asthma

Asthma

United States, Canada, Czechia, Hungary, Poland, Russian Federation, South Africa, Ukraine
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Long-Term Safety Study of Fluticasone Propionate (Fp) Multidose Dry Powder Inhaler (MDPI) and Fluticasone Propionate/Salmeterol (FS) MDPI in Patients With Persistent Asthma

Persistent Asthma

United States
Chonbuk National University Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

Effectiveness of Aripiprazole Long-acting Injection in Recent Onset and Chronic Schizophrenia Patients

Schizophrenia

Korea, Republic of
National Jewish Health

Completed

Sub-Sensitivity to Long-Acting Bronchodilators (LABA)

Asthma

United States
AstraZeneca
Parexel

Completed

A Single Inhalation Dose Study to Assess Efficacy, Pharmacokinetics (PK), Safety and Tolerability of AZD8871 in Patients With Long-term Lung Diseases.

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Vanguard Research Group
Otsuka America Pharmaceutical

Completed

Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics (PRELAPSE)

Schizophrenia

United States
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC /VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Germany, Czechia
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, United States, Netherlands, Czechia
UMC Utrecht

Completed

European Long-acting Antipsychotics in Schizophrenia Trial (EULAST)

Schizophrenia

Netherlands, Norway, Austria, Belgium, Bulgaria, Czechia, Denmark, Germany, Greece, Hungary, Israel, Italy, Poland, Romania, Spain, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Tolerability of Beclomethasone Dipropionate 100 µg + Formoterol 6 µg pMDI Via HFA-134a Vs. Budesonide 160 µg + Formoterol 4,5 µg Dry Powder Via Turbuhaler®. (Symbicort®)

Bronchial Asthma

Austria, Poland, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

EFFICACY AND TOLERABILITY OF BECLOMETHASONE DIPROPIONATE 100 µg + FORMOTEROL 6 µg pMDI VIA HFA-134a vs. FLUTICASONE 125 µg + SALMETEROL 25 µg pMDI

Bronchial Asthma

Poland, Ukraine
Oregon Health and Science University
Merck Women's Health Investigator Initiated Studies Program

Completed

Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users (Tamoxifen/BTB)

Bleeding | Breakthrough Bleeding | Implants

United States
GlaxoSmithKline

Completed

A 24 Week Efficacy Study of Inhaled Umeclidinium (UMEC) in Patients of Chronic Obstructive Pulmonary Disease (COPD) Using a Novel Dry Powder Inhaler (NDPI)

Pulmonary Disease, Chronic Obstructive

China, Korea, Republic of
GlaxoSmithKline

Withdrawn

Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study (LEGEND)

Pulmonary Disease, Chronic Obstructive

United States
Huazhong University of Science and Technology

Unknown

The Effect of Long-acting Antipsychotics on Schizophrenia Patients With Violence Risk

Schizophrenia

China
University Hospitals Cleveland Medical Center

Completed

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness (CAL-C)

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Medication Adherence | Medication Non-Adherence

United States
Boehringer Ingelheim

Completed

Effectiveness of Triple Therapy in COPD

Pulmonary Disease, Chronic Obstructive

United Kingdom
Federal State Budgetary Institution, Pulmonology...
Moscow State University of Medicine and Dentistry; National Medical Research... and other collaborators

Unknown

Methacholine, Long-acting M-cholinolytic and beta2-agonist on the Activity of Beta-receptors in Healthy Volunteers

Health, Subjective | Hyperreactivity, Bronchial

Russian Federation
Imperial College London
AstraZeneca

Completed

Effect of Symbicort on GR Localisation in Asthma

Asthma

United Kingdom
Novartis Pharmaceuticals

Completed

A 1-year Multi-center, Prospective, Cohort Study in Patients With Chronic Obstructive Pulmonary Disease Treated With Long-acting Bronchodilator

COPD

China
AstraZeneca
Parexel

Completed

Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871

Chronic Obstructive Pulmonary Disease COPD

Germany, United Kingdom
University of Padova
Azienda Ospedaliera di Padova

Unknown

GLP-1 REceptor Agonists and Real World EvIdeNce (GLP-1REWIN)

Type 2 Diabetes

Italy
Abdi İbrahim Otsuka

Completed

Effects of Aripiprazole (LAI) on Phychosocial/Cognitive Functioning, pt Reported AcceptabilityofTreatment in Sch (ARILAI)

Schizophrenia

Turkey
AstraZeneca
Parexel

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects

Chronic Obstructive Pulmonary Disease

United Kingdom

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