Search clinical trials for: low-grade squamous intraepithelial lesions

Total 7365 results

University of Zagreb
University Clinical Center Tuzla

Completed

Effect of Alpha-lipoic Acid on Regression of Low-grade Squamous Intraepithelial Lesions (LSIL)

Low-Grade Squamous Intraepithelial Lesions

Bosnia and Herzegovina, Croatia
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Detecting Anal and Genital Human Papillomavirus Infection and Squamous Intraepithelial Lesions in HIV-Positive Patients Enrolled in AIDS Cancer Clinical Trials

Sarcoma | Lymphoma | Precancerous Condition | Aids-related Malignancies

United States
Barretos Cancer Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo; Farmoquimica S.A.; Hospital...

Not yet recruiting

Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod

Biomarkers | HSIL, High-Grade Squamous Intraepithelial Lesions | Vaginal Microbiome
Peking Union Medical College Hospital
Obstetrics & Gynecology Hospital of Fudan University

Not yet recruiting

Laser Ablation in the Treatment of High-grade Cervical Lesions

High-Grade Squamous Intraepithelial Lesions
Newish Technology (Beijing) Co., Ltd.

Recruiting

NWRD08 DNA Plasmid for HPV-16 and/or HPV-18 Related Cervical HSIL

High-grade Squamous Intraepithelial Lesion (HSIL)

China
Emory University
Georgia Center for Oncology Research & Education

Not yet recruiting

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

Human Immunodeficiency Virus | Human Papilloma Virus | Anal Intraepithelial Neoplasia | High-Grade Squamous Intraepithelial Lesions

United States
Frantz Viral Therapeutics, LLC
Anal Dysplasia Clinic MidWest; Laser Surgery Care, LLC

Recruiting

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants (ART-AIN IIB-2)

Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL | Anal HPV Infection

United States
General University Hospital, Prague

Recruiting

Regression of Cervical Precancerous Lesions and Associated Risk Factors (RECER)

HPV | CIN2 | CIN3 | Cervix Uteri SIL

Czechia
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
First Affiliated Hospital of Wenzhou Medical University

Recruiting

Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection

HPV Infection | HPV-Related Cervical Carcinoma | Photodynamic Therapy | Low-Grade Squamous Intraepithelial Lesions

China
David Finch
Lancashire Teaching Hospitals NHS Foundation Trust

Not yet recruiting

COrSIcA: Disease Measurement

Anal Intraepithelial Neoplasia | Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL
Fujian Maternity and Child Health Hospital

Recruiting

Prognostic Study of HPV Virus Integration in Women With HSIL

HPV Infection | Virus Integration | HSIL, High Grade Squamous Intraepithelial Lesions

China
Institute of HIV Research and Innovation Foundation...
National Institutes of Health (NIH); amfAR, The Foundation for AIDS Research

Recruiting

Anal HSIL Screening Algorithm (0007/65)

Anal High-grade Squamous Intraepithelial Lesion

Thailand
Catharina Ziekenhuis Eindhoven
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting... and other collaborators

Recruiting

Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment (PRedICT-TOPIC)

Cervical Intraepithelial Neoplasia | CIN 2/3 | Cervical Intraepithelial Neoplasia Grade 2/3 | Cervical High Grade Squamous Intraepithelial Lesion

Netherlands
Miquel Angel Pavon Ribas
Catalan Institute of Health; Hospital del Mar

Recruiting

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III) | Human Papillomavirus (HPV) Infections | High-risk HPV | HPV-16/ 18

Spain
Fujian Maternity and Child Health Hospital

Recruiting

Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection

HPV Infection | LSIL, Low-Grade Squamous Intraepithelial Lesions | HSIL, High-Grade Squamous Intraepithelial Lesions | Virus Integration

China
Fujian Maternity and Child Health Hospital

Recruiting

A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSIL

HPV Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Viral Load

China
Fujian Maternity and Child Health Hospital

Recruiting

Effect of HPV Integration on Prognosis of Young Women With CIN2 in China

Cervical Intraepithelial Neoplasia | HPV Infection | Virus Integration | HSIL, High Grade Squamous Intraepithelial Lesions

China
Peking University People's Hospital
Hangzhou Newhorizon Health Technology Co., Ltd.; Hangzhou Mingze Medical Research... and other collaborators

Recruiting

Clinical Evaluation of Detection of High Risk HPV in Urine (Urine-hrHPV)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Human Papilloma Virus | Adenocarcinoma in Situ | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia, Grade III | Atypical... and other conditions

China
Tongji Hospital

Recruiting

Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions

Laser Burn | Squamous Intraepithelial Lesions

China
Institut de Cancérologie de Lorraine

Recruiting

Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia (PhotodiVIN)

Vulvar Intraepithelial Neoplasia | Vulvar High Grade Squamous Intraepithelial Lesion | Differentiated Vulvar Intraepithelial Neoplasia

France
University of California, San Francisco
National Cancer Institute (NCI); US-Latin American-Caribbean HIV/HPV-Cancer...

Recruiting

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico (CAMPO-101)

HIV Infection | High Grade Cervical Intraepithelial Neoplasia | AIDS-Related Anal Carcinoma | AIDS-Related Cervical Carcinoma | High Grade Anal Intraepithelial Neoplasia

Puerto Rico, Mexico
University Fernando Pessoa

Recruiting

ANAL PRECANCEROUS LESIONS IN HIGH-RISK PATIENTS. (PACCO)

HSIL, High Grade Squamous Intraepithelial Lesions | AIN3 | AIN2

Portugal
Fujian Maternity and Child Health Hospital

Recruiting

HPV Viral Load in Predicting the Prognosis of LSIL

HPV Infection | LSIL, Low-Grade Squamous Intraepithelial Lesions | Viral Load

China
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Conservative Management of HSIL in Patients With Future Pregnancy Aspiration

Cervical Intraepithelial Neoplasia | Uterine Cervical Dysplasia | Squamous Intraepithelial Lesions of the Cervix

Spain
Uriach Consumer Healthcare
Hospital General Universitario Gregorio Marañon; Hospital Universitario 12... and other collaborators

Not yet recruiting

Efficacy of Intravaginal Carboxymethyl-β-glucan and Polycarbophil on Low-grade Cervical Lesions (GLUCANCIN) (GLUCANCIN)

Human Papilloma Virus

Spain
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia | Cervical Squamous Cell Carcinoma In Situ | Cervical Squamous Intraepithelial Neoplasia 2

United States
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Intraoperative HPV Testing Evaluation

Recurrence | HSIL, High Grade Squamous Intraepithelial Lesions
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
Baylor College of Medicine
Medical University of South Carolina; M.D. Anderson Cancer Center; The University... and other collaborators

Completed

The Effectiveness of High Resolution Microendoscopy for People Living With HIV

Anal High Grade Squamous Intraepithelial Lesion

United States
National Cancer Institute (NCI)

Active, not recruiting

Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia Grade 2/3 | High Grade Cervical Intraepithelial Neoplasia | Cervical Squamous Cell Carcinoma In Situ | Cervical Squamous Intraepithelial Neoplasia 2

United States
National Cancer Institute (NCI)

Enrolling by invitation

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

Cervical Intraepithelial Neoplasia | Oropharyngeal Neoplasms | Squamous Intraepithelial Lesions of the Cervix | Cervical Neoplasms | Hematologic Malignacies

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

Cervical Intraepithelial Neoplasia | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Vaginal Adenocarcinoma | Vulvar Intraepithelial Neoplasia | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical... and other conditions

United States
Sichuan Cancer Hospital and Research Institute

Completed

Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL

High-Grade Squamous Intraepithelial Lesions

China
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; Inovio Pharmaceuticals

Active, not recruiting

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Anal Intraepithelial Neoplasia | High Grade Squamous Intraepithelial Neoplasia | HIV Positivity | Human Papillomavirus-16 Positive | Human Papillomavirus-18 Positive

United States, Puerto Rico
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
Centre Hospitalier Universitaire de Nice

Terminated

Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors

Vulvar Intraepithelial Neoplasia | Vulvar Mucosa Lesions

France
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Active, not recruiting

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

HIV Infection | Anal Intraepithelial Neoplasia | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, San Francisco; University... and other collaborators

Active, not recruiting

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions (ANCHOR)

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Peking University People's Hospital
BeijingNewBiorayTechnologyCo.,Ltd.; Hangzhou Newhorizon Health Technology Co...

Active, not recruiting

Primary Cervical Cancer Screening by Self-sampling HPV Test (PREVENT)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Adenocarcinoma in Situ | Low-Grade Squamous Intraepithelial Lesions | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia... and other conditions

China
University of Arkansas

Completed

A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions

Cervical Intraepithelial Neoplasia

United States
Sunnybrook Health Sciences Centre
Merck Canada Inc.

Active, not recruiting

In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?

HSIL, High-Grade Squamous Intraepithelial Lesions | Adenocarcinoma in Situ | Early Cervical Cancer

Canada
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; The...

Completed

Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions

Human Immunodeficiency Virus | High Grade Anal Canal Squamous Intraepithelial Neoplasia

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection

Infection | Precancerous Condition

United States
Hospitales Universitarios Virgen del Rocío
Instituto de Biomedicina de Sevilla

Enrolling by invitation

Seville Cohort of People Living With HIV at Risk for Anal Cancer (SeVIHanal)

Anal Squamous Intraepithelial Neoplasia

Spain
Memorial Sloan Kettering Cancer Center
Northwestern University; The City College of New York

Completed

Validation of a Health-Related Symptom Index for Persons Diagnosed With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)

Anal High-Grade Squamous Intraepithelial Lesions

United States
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
Inovio Pharmaceuticals

Completed

REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) (REVEAL 1)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Portugal, Italy, Philippines, Thailand, Slovakia, Lithuania, Estonia, Belgium, South Africa, Germany, Argentina, United Kingdom, Poland, Puerto Rico, Finland, Mexico, Peru
Inovio Pharmaceuticals

Completed

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Anal Neoplasm

United States, Canada

Search clinical trials for: low-grade squamous intraepithelial lesions

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